zeger debyser

zeger debyser

Katholieke Universiteit Leuven

H-index: 82

Europe-Belgium

About zeger debyser

zeger debyser, With an exceptional h-index of 82 and a recent h-index of 39 (since 2020), a distinguished researcher at Katholieke Universiteit Leuven, specializes in the field of virologie, HIV, drug discovery.

His recent articles reflect a diverse array of research interests and contributions to the field:

Prime editing functionally corrects cystic fibrosis-causing CFTR mutations in human organoids and airway epithelial cells

HIV integrase compacts viral DNA into biphasic condensates

Putting HIV in the big sleep with the block-and-lock strategy

New latency-promoting agents for a block-and-lock functional cure strategy

The Impact of Lens Epithelium-Derived Growth Factor p75 Dimerization on Its Tethering Function

LEDGF interacts with the NID of MeCP2 and modulates MeCP2 condensates

MX2 restricts HIV-1 and herpes simplex virus type 1 by forming cytoplasmic biomolecular condensates that mimic nuclear pore complexes

New horizons for BRD4-modulators in a block-and-lock functional cure of HIV-1 infection

zeger debyser Information

University

Position

___

Citations(all)

22692

Citations(since 2020)

5714

Cited By

19373

hIndex(all)

82

hIndex(since 2020)

39

i10Index(all)

284

i10Index(since 2020)

157

Email

University Profile Page

Katholieke Universiteit Leuven

Google Scholar

View Google Scholar Profile

zeger debyser Skills & Research Interests

virologie

HIV

drug discovery

Top articles of zeger debyser

Title

Journal

Author(s)

Publication Date

Prime editing functionally corrects cystic fibrosis-causing CFTR mutations in human organoids and airway epithelial cells

Cell Reports Medicine

Mattijs Bulcaen

Phéline Kortleven

Ronald B Liu

Giulia Maule

Elise Dreano

...

2024/5/1

HIV integrase compacts viral DNA into biphasic condensates

bioRxiv

Pauline Julika Kolbeck

Marjolein de Jager

Margherita Gallano

Tine Brouns

Ben Bekaert

...

2024

Putting HIV in the big sleep with the block-and-lock strategy

Eline Pellaers

Zeger Debyser

2024/5/1

New latency-promoting agents for a block-and-lock functional cure strategy

Eline Pellaers

Alexe Denis

Zeger Debyser

2024/5/1

The Impact of Lens Epithelium-Derived Growth Factor p75 Dimerization on Its Tethering Function

Cells

Tine Brouns

Vanda Lux

Siska Van Belle

Frauke Christ

Václav Veverka

...

2024/1/25

LEDGF interacts with the NID of MeCP2 and modulates MeCP2 condensates

bioRxiv

Saskia Lesire

Rodrigo Lata

Yannick Hoogvliets

Kune Herrebosch

Paulien Van De Velde

...

2024

MX2 restricts HIV-1 and herpes simplex virus type 1 by forming cytoplasmic biomolecular condensates that mimic nuclear pore complexes

bioRxiv

George D Moschonas

Louis Delhaye

Robin Cooreman

Franziska Hüsers

Anayat Bhat

...

2023/6/22

New horizons for BRD4-modulators in a block-and-lock functional cure of HIV-1 infection

Eline Pellaers

Lore Wils

Anayat Bhat

Julie Janssens

Frauke Christ

...

2023/9/11

Development of novel therapeutic strategies for rare CFTR mutations causing severe cystic fibrosis

Marjolein Ensinck

2023/1/26

Exploring the MeCP2-LEDGF Interaction: Implications for Transcriptional Regulation and Rett Syndrome Pathogenesis

Saskia Lesire

A Speleers

Yannnick Hoogvliets

Rodrigo Da Silva Lata

Paulien Van de Velde

...

2023/11/8

The HIV-2 OGH double reporter virus shows that HIV-2 is less cytotoxic and less sensitive to reactivation from latency than HIV-1 in cell culture

Journal of Virus Eradication

Anne Bruggemans

Gerlinde Vansant

Paulien Van de Velde

Zeger Debyser

2023/9/1

HDAC inhibitors rescue MeCP2T158M speckles in a high content screen

bioRxiv

Rodrigo Lata

Liesbeth Steegmans

Ranie Kellens

Marnik Nijs

Hugo Klaassen

...

2023/11/4

PB1704: LEDGF/P75 ASSOCIATED WITH CHEMORESISTANCE IN MIXED-LINEAGE LEUKEMIA

HemaSphere

Muluembet Akele

Siska Van Belle

Alessandro Canella

Frauke Christ

Zeger Debyser

2023/8/1

P326: A DUAL ROLE FOR PSIP1 IN T-ALL

HemaSphere

Lisa Demoen

Filip Matthijssens

Lindy Reunes

Zeger Debyser

Steven Goossens

...

2023/8/1

SINGLE VIRUS IMAGING OF HIV‐1 NUCLEAR IMPORT AND ITS IMPACT ON INTEGRATION SITE SELECTION

Wout Hannes

Anayat Bhat

Iva Nombela

Barbara Van Remoortel

Paulie Van de Velde

...

2023/10/3

The molecular interaction between LEDGF and MeCP2 in the Rett Syndrome

Yannick Hoogvliets

Saskia Lesire

Paulien Van de Velde

Frauke Christ

Zeger Debyser

2023/7/8

Particle-based phasor-FLIM-FRET resolves protein-protein interactions inside single viral particles

Biophysical Reports

Quinten Coucke

Nagma Parveen

Guillermo Solis Fernandez

Chen Qian

Johan Hofkens

...

2023

WS16. 01 Correction of the drug-refractory CFTR mutation L227R by prime editing

Journal of Cystic Fibrosis

M Bulcaen

MM Ensinck

L De Keersmaecker

G Maule

AS Ramalho

...

2022/6/1

BET-Independent Murine Leukemia Virus Integration Is Retargeted In Vivo and Selects Distinct Genomic Elements for Lymphomagenesis

Microbiology Spectrum

Ivan Nombela

Martine Michiels

Dominique Van Looveren

Lukas Marcelis

Sara El Ashkar

...

2022/8/31

Studying an array of biological questions at the nanoscale with Expansion Microscopy: From cells to viruses

Aline Acke

2022/2/3

See List of Professors in zeger debyser University(Katholieke Universiteit Leuven)