Atsuo T. Sasaki

Atsuo T. Sasaki

University of Cincinnati

H-index: 46

North America-United States

About Atsuo T. Sasaki

Atsuo T. Sasaki, With an exceptional h-index of 46 and a recent h-index of 30 (since 2020), a distinguished researcher at University of Cincinnati, specializes in the field of GTP-Metabolism and Phosphoinositide Signaling.

His recent articles reflect a diverse array of research interests and contributions to the field:

A high dose KRP203 induces cytoplasmic vacuoles associated with altered phosphoinositide segregation and endosome expansion

Homogeneous luminescent quantitation of cellular guanosine and adenosine triphosphates (GTP and ATP) using QT-LucGTP&ATP assay

Multimodal action of KRP203 on phosphoinositide kinases in vitro and in cells

Functional molecular evolution of a GTP sensing kinase: PI5P4Kβ

Abstract A022: Translation initiation factor 2B (eIF2B) stimulates mutant KRAS function in cancer

Epigenetic upregulation of Schlafen11 renders WNT-and SHH-activated medulloblastomas sensitive to cisplatin

Methods of controlling bodyweight by modulating phosphatidylinositol 5-phosphate 4-kinase beta activity

IMPDH inhibition activates TLR‐VCAM1 pathway and suppresses the development of MLL‐fusion leukemia

Atsuo T. Sasaki Information

University

Position

College of Medicine

Citations(all)

14967

Citations(since 2020)

4441

Cited By

12239

hIndex(all)

46

hIndex(since 2020)

30

i10Index(all)

65

i10Index(since 2020)

53

Email

University Profile Page

Google Scholar

Atsuo T. Sasaki Skills & Research Interests

GTP-Metabolism and Phosphoinositide Signaling

Top articles of Atsuo T. Sasaki

A high dose KRP203 induces cytoplasmic vacuoles associated with altered phosphoinositide segregation and endosome expansion

Biochemical and Biophysical Research Communications

2024/4/27

Homogeneous luminescent quantitation of cellular guanosine and adenosine triphosphates (GTP and ATP) using QT-LucGTP&ATP assay

Analytical and bioanalytical chemistry

2023/11

Multimodal action of KRP203 on phosphoinositide kinases in vitro and in cells

Biochemical and Biophysical Research Communications

2023/10/30

Functional molecular evolution of a GTP sensing kinase: PI5P4Kβ

The FEBS journal

2023/9

Abstract A022: Translation initiation factor 2B (eIF2B) stimulates mutant KRAS function in cancer

Molecular Cancer Research

2023/5/1

Epigenetic upregulation of Schlafen11 renders WNT-and SHH-activated medulloblastomas sensitive to cisplatin

Neuro-oncology

2023/5/1

Methods of controlling bodyweight by modulating phosphatidylinositol 5-phosphate 4-kinase beta activity

2023/3/30

IMPDH inhibition activates TLR‐VCAM1 pathway and suppresses the development of MLL‐fusion leukemia

EMBO Molecular Medicine

2023/1/11

Beyond Warburg: LDHA activates RAC for tumour growth

Nature metabolism

2022/12

Drug discovery targeting GTP metabolism for cancer and infectious diseases using X-ray crystallography and cryo-EM

Acta Crystallographica Section A: Foundations of Crystallography

2022/7/7

The GTP responsiveness of PI5P4Kβ evolved from a compromised trade-off between activity and specificity

Structure

2022/6/2

TGF-β-dependent reprogramming of amino acid metabolism induces epithelial–mesenchymal transition in non-small cell lung cancers

Communications biology

2021/6/24

Integration of Molecular Analysis, Cutting-edge Mouse Genetic Models and Proton Therapy to Improve Outcomes for Glioma Patients

2021/4/30

Targeting Energy Metabolism to Overcome Therapeutic Resistance of Glioblastoma and Tumor-associated Edema

2021/4/30

Emerging roles of wild-type and mutant IDH1 in growth, metabolism and therapeutics of glioma

2021/4/30

Reuse of molecules for glioblastoma therapy

2021/1/28

SI-MOIRAI: a new method to identify and quantify the metabolic fate of nucleotides

The Journal of Biochemistry

2021/12

Mycophenolate mofetil hepatotoxicity associated with mitochondrial abnormality in liver transplant recipients and mice

Journal of Pediatric Gastroenterology and Nutrition

2021/10/1

Divergent mechanisms activating RAS and small GTPases through post-translational modification

2021/7/8

Schlafen 11 predicts response to platinum-based chemotherapy in gastric cancers

British Journal of Cancer

2021/7/6

See List of Professors in Atsuo T. Sasaki University(University of Cincinnati)

Co-Authors

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