Junko Murai

About Junko Murai

Junko Murai, With an exceptional h-index of 34 and a recent h-index of 31 (since 2020), a distinguished researcher at Keio University, specializes in the field of SLFN11, DNA damage, cell cycle, panda, tennis.

His recent articles reflect a diverse array of research interests and contributions to the field:

Schlafen 11 further sensitizes BRCA-deficient cells to PARP inhibitors through single-strand DNA gap accumulation behind replication forks

SLFN11 is a BRCA Independent Biomarker for the Response to Platinum-Based Chemotherapy in High-Grade Serous Ovarian Cancer and Clear Cell Ovarian …

Epigenetic upregulation of Schlafen11 renders WNT-and SHH-activated medulloblastomas sensitive to cisplatin

BRCAness, homologous recombination deficiencies, and synthetic lethality

Schlafen family member 11 indicates favorable prognosis of patients with head and neck cancer following platinum-based chemoradiotherapy

The germline factor DDX4 contributes to the chemoresistance of small cell lung cancer cells

Synergistic effects of PARP inhibitors by Schlafen 11 and BRCA2-deficiency through accumulation of single-strand DNA gaps behind a fork

Metabolic clogging of mannose triggers dNTP loss and genomic instability in human cancer cells

Junko Murai Information

University

Position

Project Associate Professor

Citations(all)

7345

Citations(since 2020)

4703

Cited By

4573

hIndex(all)

34

hIndex(since 2020)

31

i10Index(all)

51

i10Index(since 2020)

49

Email

University Profile Page

Google Scholar

Junko Murai Skills & Research Interests

SLFN11

DNA damage

cell cycle

panda

tennis

Top articles of Junko Murai

Schlafen 11 further sensitizes BRCA-deficient cells to PARP inhibitors through single-strand DNA gap accumulation behind replication forks

2024/2/2

Junko Murai
Junko Murai

H-Index: 27

Yusuke Kobayashi
Yusuke Kobayashi

H-Index: 12

SLFN11 is a BRCA Independent Biomarker for the Response to Platinum-Based Chemotherapy in High-Grade Serous Ovarian Cancer and Clear Cell Ovarian …

Molecular cancer therapeutics

2024/1/3

Junko Murai
Junko Murai

H-Index: 27

Kosuke Yoshihara
Kosuke Yoshihara

H-Index: 27

Epigenetic upregulation of Schlafen11 renders WNT-and SHH-activated medulloblastomas sensitive to cisplatin

Neuro-oncology

2023/5/1

Junko Murai
Junko Murai

H-Index: 27

Tetsuya Yamamoto
Tetsuya Yamamoto

H-Index: 16

BRCAness, homologous recombination deficiencies, and synthetic lethality

Cancer Research

2023/4/14

Junko Murai
Junko Murai

H-Index: 27

Schlafen family member 11 indicates favorable prognosis of patients with head and neck cancer following platinum-based chemoradiotherapy

Frontiers in oncology

2023/1/19

The germline factor DDX4 contributes to the chemoresistance of small cell lung cancer cells

Communications Biology

2023/1/18

Synergistic effects of PARP inhibitors by Schlafen 11 and BRCA2-deficiency through accumulation of single-strand DNA gaps behind a fork

bioRxiv

2023

Junko Murai
Junko Murai

H-Index: 27

Metabolic clogging of mannose triggers dNTP loss and genomic instability in human cancer cells

Elife

2023/7/18

Junko Murai
Junko Murai

H-Index: 27

The crucial role of single-stranded DNA binding in enhancing sensitivity to DNA-damaging agents for Schlafen 11 and Schlafen 13

Iscience

2023/12/15

10199-SPDR-2 PERSONALIZED SYNTHETIC LETHALITY INDUCED BY TARGETING ATR-CHK1 IN MEDULLOBLASTOMAS IDENTIFIED BY IMPLEMENTATION OF SLFN11 IMMUNOHISTOCHEMISTRY

Neuro-Oncology Advances

2023/12/1

Junko Murai
Junko Murai

H-Index: 27

Schlafen 11 (SLFN11) kills cancer cells undergoing unscheduled re-replication

Molecular cancer therapeutics

2023/8/1

Junko Murai
Junko Murai

H-Index: 27

263 SLFN11 is a possible biomarker of sensitivity to DNA-targeted regents in CD30-positive mycosis fungoides and Sezary syndrome

Journal of Investigative Dermatology

2023/5/1

SPDR-4 SLFN11 RENDERS MEDULLOBLASTOMA SENSITIVE TO DNA DAMAGE CHEMOTHERAPIES

Neuro-Oncology Advances

2022/12

Junko Murai
Junko Murai

H-Index: 27

Metabolic clogging of mannose triggers genomic instability via dNTP loss in human cancer cells

bioRxiv

2022/10/17

Junko Murai
Junko Murai

H-Index: 27

Successful Treatment of Acute Uric Acid Nephropathy with Rasburicase in a Primary Central Nervous System Lymphoma Patient Showing a Dramatic Response to Methotrexate—Case Report

Journal of Clinical Medicine

2022/9/22

Junko Murai
Junko Murai

H-Index: 27

Hiroshi Shimizu
Hiroshi Shimizu

H-Index: 29

Reconsidering the mechanisms of action of PARP inhibitors based on clinical outcomes

2022/9

Junko Murai
Junko Murai

H-Index: 27

Prognostic impact of Schlafen 11 in bladder cancer patients treated with platinum‐based chemotherapy

Cancer Science

2022/2

Schlafen 11, a crucial determinant of sensitivity to DNA damaging agents~ basic and clinic~

Fujita Medical Journal

2022

Junko Murai
Junko Murai

H-Index: 27

Schlafen 11 expression in human acute leukemia cells with gain-of-function mutations in the interferon-JAK signaling pathway

Iscience

2021/10/22

Junko Murai
Junko Murai

H-Index: 27

Schlafen 11 predicts response to platinum-based chemotherapy in gastric cancers

British Journal of Cancer

2021/7/6

See List of Professors in Junko Murai University(Keio University)