Ashley Pike

Ashley Pike

University of Oxford

H-index: 40

Europe-United Kingdom

About Ashley Pike

Ashley Pike, With an exceptional h-index of 40 and a recent h-index of 26 (since 2020), a distinguished researcher at University of Oxford, specializes in the field of membrane proteins, structural biology.

His recent articles reflect a diverse array of research interests and contributions to the field:

Structural basis of the mechanism and inhibition of a human ceramide synthase

Transport and inhibition of the sphingosine-1-phosphate exporter SPNS2

Extracellular modulation of TREK-2 activity with nanobodies provides insight into the mechanisms of K2P channel regulation

Structural characterization of human urea transporters UT-A and UT-B and their inhibition

Structure and function of the SIT1 proline transporter in complex with the COVID-19 receptor ACE2 (preprint)

The structural basis of fatty acid elongation by the ELOVL elongases

A lower X-gate in TASK channels traps inhibitors within the vestibule

A new paradigm for Prelamin A proteolytic processing by ZMPSTE24: the upstream SY^ LL cleavage occurs first and there is no CaaX processing by ZMPSTE24

Ashley Pike Information

University

Position

Structural Genomics Consortium -

Citations(all)

13063

Citations(since 2020)

3100

Cited By

11076

hIndex(all)

40

hIndex(since 2020)

26

i10Index(all)

48

i10Index(since 2020)

37

Email

University Profile Page

University of Oxford

Google Scholar

View Google Scholar Profile

Ashley Pike Skills & Research Interests

membrane proteins

structural biology

Top articles of Ashley Pike

Title

Journal

Author(s)

Publication Date

Structural basis of the mechanism and inhibition of a human ceramide synthase

bioRxiv

Tomas C Pascoa

Ashley CW Pike

Christofer S Tautermann

Gamma Chi

Michael Traub

...

2023/12/2

Transport and inhibition of the sphingosine-1-phosphate exporter SPNS2

David Sauer

Huanyu Li

Ashley Pike

Yung-Ning Chang

Dheeraj Prakaash

...

2023/11/21

Extracellular modulation of TREK-2 activity with nanobodies provides insight into the mechanisms of K2P channel regulation

bioRxiv

Karin EJ Rödström

Alexander Cloake

Janina Sörmann

Agnese Baronina

Kathryn HM Smith

...

2023/10/21

Structural characterization of human urea transporters UT-A and UT-B and their inhibition

Science Advances

Gamma Chi

Larissa Dietz

Haiping Tang

Matthew Snee

Andreea Scacioc

...

2023/9/29

Structure and function of the SIT1 proline transporter in complex with the COVID-19 receptor ACE2 (preprint)

bioRxiv

Huanyu Z Li

Ashley CW Pike

Gamma Chi

Jesper S Hansen

Sarah G Lee

...

2023

The structural basis of fatty acid elongation by the ELOVL elongases

Nature structural & molecular biology

Laiyin Nie

Tomas C Pascoa

Ashley CW Pike

Simon R Bushell

Andrew Quigley

...

2021/6

A lower X-gate in TASK channels traps inhibitors within the vestibule

Nature

Karin EJ Rödström

Aytuğ K Kiper

Wei Zhang

Susanne Rinne

Ashley CW Pike

...

2020/6/18

A new paradigm for Prelamin A proteolytic processing by ZMPSTE24: the upstream SY^ LL cleavage occurs first and there is no CaaX processing by ZMPSTE24

bioRxiv

Laiyin Nie

Eric Spear

Timothy D Babatz

Andrew Quigley

Yin Yao Dong

...

2020/5/13

Lipid interactions of a ciliary membrane TRP channel: simulation and structural studies of polycystin-2

Structure

Qinrui Wang

Robin A Corey

George Hedger

Prafulla Aryal

Mariana Grieben

...

2020/2/4

See List of Professors in Ashley Pike University(University of Oxford)

Co-Authors

H-index: 199
Jan-Ake Gustafsson

Jan-Ake Gustafsson

University of Houston

H-index: 110
Stefan Knapp

Stefan Knapp

Goethe-Universität Frankfurt am Main

H-index: 108
Mark S.P. Sansom

Mark S.P. Sansom

University of Oxford

H-index: 84
Geoffrey Greene

Geoffrey Greene

University of Chicago

H-index: 66
Oleg Fedorov

Oleg Fedorov

University of Oxford

H-index: 53
Opher Gileadi

Opher Gileadi

University of Oxford

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