Anna-Leigh Brown

RNA aptamer reveals nuclear TDP-43 pathology is an early aggregation event that coincides with STMN-2 cryptic splicing and precedes clinical manifestation in ALS

Mis-spliced transcripts generate de novo proteins in TDP-43–related ALS/FTD

Unexpected frequency of the pathogenic AR CAG repeat expansion in the general population

The era of cryptic exons: implications for ALS-FTD

Solving A Decade-Long Mystery: Neurons Hold The Key To Rare Neurological Diseases

TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A

NOS1AP is a novel molecular target and critical factor in TDP-43 pathology

Cell environment shapes TDP-43 function with implications in neuronal and muscle disease