Sahba Seddighi

Mis-spliced transcripts generate de novo proteins in TDP-43–related ALS/FTD

FTLD targets brain regions expressing recently evolved genes

Disentangling the genetic overlap and causal relationships between primary open-angle glaucoma, brain morphology and four major neurodegenerative disorders

Variant biomarker discovery using mass spectrometry-based proteogenomics

TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A

Developing biomarkers of TDP‐43‐related splicing dysfunction in frontotemporal dementia

Evidence of a Causal Association Between Cancer and Alzheimer’s Disease: A Mendelian Randomization Analysis (2597)