Amin Rostami-Hodjegan

Amin Rostami-Hodjegan

Manchester University

H-index: 81

North America-United States

About Amin Rostami-Hodjegan

Amin Rostami-Hodjegan, With an exceptional h-index of 81 and a recent h-index of 55 (since 2020), a distinguished researcher at Manchester University, specializes in the field of Translational Modelling in Drug Development, PBPK/QSP.

His recent articles reflect a diverse array of research interests and contributions to the field:

Facing the facts of altered plasma protein binding: Do current models correctly predict changes in fraction unbound in special populations?

The Role of Model Master Files for Sharing, Acceptance, and Communication with FDA

Virtual twins for model‐informed precision dosing of clozapine in patients with treatment‐resistant schizophrenia

Experience Learned and Perspectives on Using Model-Integrated Evidence in the Regulatory Context for Generic Drug Products—a Meeting Report

Complementarity of two proteomic data analysis tools in the identification of drug-metabolising enzymes and transporters in human liver

Quantitative proteomics of pharmacokinetics (PK) and pharmacodynamics (PD) targets in liver, small intestine, colon, appendiceal and peritoneal cancer

On the Verge of Impossibility: Accounting for Variability Arising from Permutations of Comorbidities that Affect the Fate of Drugs in the Human Body

Development of 4‐Pyridoxic Acid PBPK Model to Support Biomarker‐Informed Evaluation of OAT1/3 Inhibition and Effect of Chronic Kidney Disease

Amin Rostami-Hodjegan Information

University

Position

Professor of Systems Pharmacology UK

Citations(all)

22756

Citations(since 2020)

9833

Cited By

16511

hIndex(all)

81

hIndex(since 2020)

55

i10Index(all)

272

i10Index(since 2020)

213

Email

University Profile Page

Google Scholar

Amin Rostami-Hodjegan Skills & Research Interests

Translational Modelling in Drug Development

PBPK/QSP

Top articles of Amin Rostami-Hodjegan

Title

Journal

Author(s)

Publication Date

Facing the facts of altered plasma protein binding: Do current models correctly predict changes in fraction unbound in special populations?

Journal of Pharmaceutical Sciences

Jokha Al-Qassabi

Shawn Pei Feng Tan

Patcharapan Phonboon

Aleksandra Galetin

Amin Rostami-Hodjegan

...

2024/2/28

The Role of Model Master Files for Sharing, Acceptance, and Communication with FDA

The AAPS Journal

Lanyan Fang

Yuqing Gong

Andrew C Hooker

Viera Lukacova

Amin Rostami-Hodjegan

...

2024/2/27

Virtual twins for model‐informed precision dosing of clozapine in patients with treatment‐resistant schizophrenia

CPT: Pharmacometrics & Systems Pharmacology

Sam Mostafa

Reza Rafizadeh

Thomas M Polasek

Chad A Bousman

Amin Rostami‐Hodjegan

...

2024/1/19

Experience Learned and Perspectives on Using Model-Integrated Evidence in the Regulatory Context for Generic Drug Products—a Meeting Report

The AAPS Journal

Eleftheria Tsakalozou

Lanyan Fang

Youwei Bi

Michiel van den Heuvel

Tausif Ahmed

...

2024/1/10

Complementarity of two proteomic data analysis tools in the identification of drug-metabolising enzymes and transporters in human liver

Molecular Omics

Areti-Maria Vasilogianni

Sarah Alrubia

Eman El-Khateeb

Zubida M Al-Majdoub

Narciso Couto

...

2024

Quantitative proteomics of pharmacokinetics (PK) and pharmacodynamics (PD) targets in liver, small intestine, colon, appendiceal and peritoneal cancer

AM Vasilogianni

C Demonacos

Omer Aziz

SA Peters

J Barber

...

2023

On the Verge of Impossibility: Accounting for Variability Arising from Permutations of Comorbidities that Affect the Fate of Drugs in the Human Body

Amin Rostami-Hodjegan

Brahim Achour

2023/5/27

Development of 4‐Pyridoxic Acid PBPK Model to Support Biomarker‐Informed Evaluation of OAT1/3 Inhibition and Effect of Chronic Kidney Disease

Clinical Pharmacology & Therapeutics

Shawn Pei Feng Tan

Marie‐Emilie Willemin

Jan Snoeys

Hong Shen

Amin Rostami‐Hodjegan

...

2023/12

Pharmacokinetics under the COVID‐19 storm

British Journal of Clinical Pharmacology

Venkatesh Pilla Reddy

Eman El‐Khateeb

Heeseung Jo

Natalie Giovino

Emily Lythgoe

...

2020/1

Seeing what is behind the smokescreen: A systematic review of methodological aspects of smoking interaction studies over the last three decades and implications for future …

Robert Hermann

Amin Rostami‐Hodjegan

Ping Zhao

Isabelle Ragueneau‐Majlessi

2023/5

Understanding Discordance between In Vitro Dissolution, Local Gut and Systemic Bioequivalence of Budesonide in Healthy and Crohn’s Disease Patients through PBPK Modeling

Pharmaceutics

Chunyan Han

Tiancheng Sun

Siri Kalyan Chirumamilla

Frederic Y Bois

Mandy Xu

...

2023/8/30

Toward systems-informed models for biologics disposition: covariates of the abundance of the neonatal Fc receptor (FcRn) in human tissues and implications for pharmacokinetic …

European Journal of Pharmaceutical Sciences

Jill Barber

Zubida M Al-Majdoub

Narciso Couto

Martyn Howard

Yasmine Elmorsi

...

2023/3/1

Harnessing the Power of Physiologically Based Pharmacokinetic Modeling to Explore Potential Discordance between in vitro Dissolution, Local Gut vs Systemic Bioequivalence in …

Chunyan Han

Tiancheng Sun

Sirikalyan Chirumamilla

Frederic Bois

Mandy Xu

...

2023/8/4

Proteomic quantification of receptor tyrosine kinases involved in the development and progression of colorectal cancer liver metastasis

Frontiers in Oncology

Areti-Maria Vasilogianni

Zubida M Al-Majdoub

Brahim Achour

Sheila Annie Peters

Amin Rostami-Hodjegan

...

2023/2/20

Linking in vitro–in vivo extrapolations with physiologically based modeling to inform drug and formulation development

Rodrigo Cristofoletti

Amin Rostami‐Hodjegan

2023/8

Delineating gene–environment effects using virtual twins of patients treated with clozapine

CPT: Pharmacometrics & Systems Pharmacology

Sam Mostafa

Thomas M Polasek

Chad Bousman

Amin Rostami‐Hodjegan

Leslie J Sheffield

...

2023/2

In‐depth analysis of patterns in selection of different physiologically‐based pharmacokinetic modeling tools: Part II—Assessment of model reusability and comparison between …

Biopharmaceutics & Drug Disposition

Hamza Khaled Abdelmajed Aldibani

Arham Jamaal Rajput

Amin Rostami‐Hodjegan

2023/8

The Interplay Between Drug Release and Intestinal Gut‐Wall Metabolism

Oral Drug Delivery for Modified Release Formulations

Adam S Darwich

Oliver J Hatley

Andrés Olivares‐Morales

Farzaneh Salem

Alison Margolskee

...

2022/4/20

Methods and apparatus for generating a virtual model of xenobiotic exposure using transcriptomics analysis of liquid biopsy samples

2022/7/7

Effect of chronic kidney disease on the renal secretion via organic anion transporters 1/3: implications for physiologically‐based pharmacokinetic modeling and dose adjustment

Clinical Pharmacology & Therapeutics

Shawn Pei Feng Tan

Daniel Scotcher

Amin Rostami‐Hodjegan

Aleksandra Galetin

2022/9

See List of Professors in Amin Rostami-Hodjegan University(Manchester University)

Co-Authors

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