Alessio Ciulli

Alessio Ciulli

University of Dundee

H-index: 50

Europe-United Kingdom

About Alessio Ciulli

Alessio Ciulli, With an exceptional h-index of 50 and a recent h-index of 40 (since 2020), a distinguished researcher at University of Dundee, specializes in the field of Chemical Biology, Structural Biology, Medicinal Chemistry, Targeted Protein Degradation, PROTACs.

His recent articles reflect a diverse array of research interests and contributions to the field:

Design of a Cereblon construct for crystallographic and biophysical studies of protein degraders

Proximity Biosensor Assay for PROTAC Ternary Complex Analysis

Targeted protein degradation via intramolecular bivalent glues

Combination of AID2 and BromoTag expands the utility of degron-based protein knockdowns

Confounding factors in targeted degradation of short-lived proteins

Ternary Complex‐Templated Dynamic Combinatorial Chemistry for the Selection and Identification of Homo‐PROTACs

Mechanism of degrader-targeted protein ubiquitinability

Bifunctional molecules for targeting Rpn11

Alessio Ciulli Information

University

Position

Professor

Citations(all)

10226

Citations(since 2020)

7614

Cited By

5091

hIndex(all)

50

hIndex(since 2020)

40

i10Index(all)

104

i10Index(since 2020)

95

Email

University Profile Page

University of Dundee

Google Scholar

View Google Scholar Profile

Alessio Ciulli Skills & Research Interests

Chemical Biology

Structural Biology

Medicinal Chemistry

Targeted Protein Degradation

PROTACs

Top articles of Alessio Ciulli

Title

Journal

Author(s)

Publication Date

Design of a Cereblon construct for crystallographic and biophysical studies of protein degraders

BioRxiv

Alena Kroupova

Valentina A. Spiteri

Hirotake Furihata

Darren Darren

Sarath Ramachandran

...

2024/1/20

Proximity Biosensor Assay for PROTAC Ternary Complex Analysis

Irene Ponzo

Alice Solda

Charlotte Crowe

Goran Dahl

Stefan Geschwindner

...

2024/3/6

Targeted protein degradation via intramolecular bivalent glues

Nature

Oliver Hsia

Matthias Hinterndorfer

Angus D Cowan

Kentaro Iso

Tasuku Ishida

...

2024/2/21

Combination of AID2 and BromoTag expands the utility of degron-based protein knockdowns

bioRxiv

Yuki Hatoyama

Moutushi Islam

Adam G Bond

Ken-Ichiro Hayashi

Alessio Ciulli

...

2024

Confounding factors in targeted degradation of short-lived proteins

bioRxiv

Vesna Vetma

Laura Casares Perez

Jan Elias

Andrea Stingu

Anju Kombara

...

2024

Ternary Complex‐Templated Dynamic Combinatorial Chemistry for the Selection and Identification of Homo‐PROTACs

Angewandte Chemie International Edition

Claudia J Diehl

Alessandra Salerno

Alessio Ciulli

2024/4/16

Mechanism of degrader-targeted protein ubiquitinability

bioRxiv

Charlotte Crowe

Mark Nakasone

Sarah Chandler

Michael H Tatham

Nikolai Makukhin

...

2024

Bifunctional molecules for targeting Rpn11

2024/3/12

Crystallization of VHL-based PROTAC-induced ternary complexes

Andre J Wijaya

William Farnaby

Alessio Ciulli

2023/1/1

Proximity-based modalities for biology and medicine

Xingui Liu

Alessio Ciulli

2023/7/14

Ternary Complex-Directed Dynamic Combinatorial Chemistry Enables Discovery of Potent VHL Homo-PROTACs

ChemRxiv

Claudia Diehl

Alessandra Salerno

Alessio Ciulli

2023/12/15

Breaking free from the crystal lattice: Structural biology in solution to study protein degraders

Kevin Haubrich

Valentina A Spiteri

William Farnaby

Frank Sobott

Alessio Ciulli

2023/4/1

The 17th EFMC Short Course on Medicinal Chemistry on Small Molecule Protein Degraders

Alessio Ciulli

Suzanne O'Connor

Chun‐Wa Chung

Ingo V Hartung

Andrea Testa

...

2023/10/17

Synthetic PROTACs based on a depsipeptide macrocycle selectively degrade cyclophilin A and inhibit HIV-1

Clara Gathmann

Lydia S Newton

Sophie Ridewood

Robert J Smith

Thomas W Hornsby

...

2023/3/15

Structure-based design of a phosphotyrosine-masked covalent ligand targeting the E3 ligase SOCS2

Nature Communications

Sarath Ramachandran

Nikolai Makukhin

Kevin Haubrich

Manjula Nagala

Beth Forrester

...

2023/10/10

Functional E3 ligase hotspots and resistance mechanisms to small-molecule degraders

Nature chemical biology

Alexander Hanzl

Ryan Casement

Hana Imrichova

Scott J Hughes

Eleonora Barone

...

2023/3

Expanding the Structural Diversity at the Phenylene Core of Ligands for the von Hippel–Lindau E3 Ubiquitin Ligase: Development of Highly Potent Hypoxia-Inducible Factor-1α …

Journal of Medicinal Chemistry

Lan Phuong Vu

Claudia J Diehl

Ryan Casement

Adam G Bond

Christian Steinebach

...

2023/9/14

Targeting cancer with small molecule pan-KRAS degraders

bioRxiv

Johannes Popow

William Farnaby

Andreas Gollner

Christiane Kofink

Gerhard Fischer

...

2023

HiBiT Cellular Thermal Shift Assay (HiBiT CETSA)

Sarath Ramachandran

Magdalena Szewczyk

Samir H Barghout

Alessio Ciulli

Dalia Barsyte-Lovejoy

...

2023/8/10

Fluorohydroxyproline derivatives useful in the preparation of proteolysis targeted chimeras

2022/2/1

See List of Professors in Alessio Ciulli University(University of Dundee)

Co-Authors

H-index: 154
Dario Alessi

Dario Alessi

University of Dundee

H-index: 133
William L. Jorgensen

William L. Jorgensen

Yale University

H-index: 129
Tom L Blundell

Tom L Blundell

University of Cambridge

H-index: 110
Stefan Knapp

Stefan Knapp

Goethe-Universität Frankfurt am Main

H-index: 98
Craig Crews

Craig Crews

Yale University

H-index: 72
Prof. Alison G. Smith

Prof. Alison G. Smith

University of Cambridge

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