Alessio Ciulli
University of Dundee
H-index: 50
Europe-United Kingdom
Top articles of Alessio Ciulli
Title | Journal | Author(s) | Publication Date |
---|---|---|---|
Design of a Cereblon construct for crystallographic and biophysical studies of protein degraders | BioRxiv | Alena Kroupova Valentina A. Spiteri Hirotake Furihata Darren Darren Sarath Ramachandran | 2024/1/20 |
Proximity Biosensor Assay for PROTAC Ternary Complex Analysis | Irene Ponzo Alice Solda Charlotte Crowe Goran Dahl Stefan Geschwindner | 2024/3/6 | |
Targeted protein degradation via intramolecular bivalent glues | Nature | Oliver Hsia Matthias Hinterndorfer Angus D Cowan Kentaro Iso Tasuku Ishida | 2024/2/21 |
Combination of AID2 and BromoTag expands the utility of degron-based protein knockdowns | bioRxiv | Yuki Hatoyama Moutushi Islam Adam G Bond Ken-Ichiro Hayashi Alessio Ciulli | 2024 |
Confounding factors in targeted degradation of short-lived proteins | bioRxiv | Vesna Vetma Laura Casares Perez Jan Elias Andrea Stingu Anju Kombara | 2024 |
Ternary Complex‐Templated Dynamic Combinatorial Chemistry for the Selection and Identification of Homo‐PROTACs | Angewandte Chemie International Edition | Claudia J Diehl Alessandra Salerno Alessio Ciulli | 2024/4/16 |
Mechanism of degrader-targeted protein ubiquitinability | bioRxiv | Charlotte Crowe Mark Nakasone Sarah Chandler Michael H Tatham Nikolai Makukhin | 2024 |
Bifunctional molecules for targeting Rpn11 | 2024/3/12 | ||
Crystallization of VHL-based PROTAC-induced ternary complexes | Andre J Wijaya William Farnaby Alessio Ciulli | 2023/1/1 | |
Proximity-based modalities for biology and medicine | Xingui Liu Alessio Ciulli | 2023/7/14 | |
Ternary Complex-Directed Dynamic Combinatorial Chemistry Enables Discovery of Potent VHL Homo-PROTACs | ChemRxiv | Claudia Diehl Alessandra Salerno Alessio Ciulli | 2023/12/15 |
Breaking free from the crystal lattice: Structural biology in solution to study protein degraders | Kevin Haubrich Valentina A Spiteri William Farnaby Frank Sobott Alessio Ciulli | 2023/4/1 | |
The 17th EFMC Short Course on Medicinal Chemistry on Small Molecule Protein Degraders | Alessio Ciulli Suzanne O'Connor Chun‐Wa Chung Ingo V Hartung Andrea Testa | 2023/10/17 | |
Synthetic PROTACs based on a depsipeptide macrocycle selectively degrade cyclophilin A and inhibit HIV-1 | Clara Gathmann Lydia S Newton Sophie Ridewood Robert J Smith Thomas W Hornsby | 2023/3/15 | |
Structure-based design of a phosphotyrosine-masked covalent ligand targeting the E3 ligase SOCS2 | Nature Communications | Sarath Ramachandran Nikolai Makukhin Kevin Haubrich Manjula Nagala Beth Forrester | 2023/10/10 |
Functional E3 ligase hotspots and resistance mechanisms to small-molecule degraders | Nature chemical biology | Alexander Hanzl Ryan Casement Hana Imrichova Scott J Hughes Eleonora Barone | 2023/3 |
Expanding the Structural Diversity at the Phenylene Core of Ligands for the von Hippel–Lindau E3 Ubiquitin Ligase: Development of Highly Potent Hypoxia-Inducible Factor-1α … | Journal of Medicinal Chemistry | Lan Phuong Vu Claudia J Diehl Ryan Casement Adam G Bond Christian Steinebach | 2023/9/14 |
Targeting cancer with small molecule pan-KRAS degraders | bioRxiv | Johannes Popow William Farnaby Andreas Gollner Christiane Kofink Gerhard Fischer | 2023 |
HiBiT Cellular Thermal Shift Assay (HiBiT CETSA) | Sarath Ramachandran Magdalena Szewczyk Samir H Barghout Alessio Ciulli Dalia Barsyte-Lovejoy | 2023/8/10 | |
Fluorohydroxyproline derivatives useful in the preparation of proteolysis targeted chimeras | 2022/2/1 |