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Aakash Saha

Aakash Saha

University of California, Riverside

H-index: 7

North America-United States

Contact Aakash Saha

About Aakash Saha

Aakash Saha, With an exceptional h-index of 7 and a recent h-index of 7 (since 2020), a distinguished researcher at University of California, Riverside, specializes in the field of Biophysics, Computational Biology, Computational Chemistry, CRISPR-Cas.

His recent articles reflect a diverse array of research interests and contributions to the field:

An alpha-helical lid guides the target DNA toward catalysis in CRISPR-Cas12a

Biophysical origin of adenine base editors’ improved editing efficiency

Folding and unfolding of an alpha-helical lid govern target double-stranded DNA break in Cas12a

The synchronized catalytic dance of CRISPR-Cas9

Structure and dynamics of off-target effects in CRISPR-Cas9

Key role of an alpha-helical lid in driving the target DNA toward catalysis in CRISPR-Cas12a

GPU-enhanced DFTB metadynamics for efficiently predicting free energies of biochemical systems

Harnessing GPU-Enhanced Simulations for Efficient DFTB Metadynamics of Biochemical Systems

Aakash Saha Information

University

Position

___

Citations(all)

278

Citations(since 2020)

278

Cited By

16

hIndex(all)

7

hIndex(since 2020)

7

i10Index(all)

7

i10Index(since 2020)

7

Email

University Profile Page

Google Scholar

Aakash Saha Skills & Research Interests

Biophysics

Computational Biology

Computational Chemistry

CRISPR-Cas

Top articles of Aakash Saha

An alpha-helical lid guides the target DNA toward catalysis in CRISPR-Cas12a

Nature Communications

2024/2/17

Aakash Saha
Aakash Saha

H-Index: 3

Mohd Ahsan
Mohd Ahsan

H-Index: 3

Michael Schmitz
Michael Schmitz

H-Index: 6

Martin Jinek
Martin Jinek

H-Index: 41

Giulia Palermo
Giulia Palermo

H-Index: 22

Biophysical origin of adenine base editors’ improved editing efficiency

Biophysical Journal

2024/2/8

Xiaoyu Chen
Xiaoyu Chen

H-Index: 3

Aakash Saha
Aakash Saha

H-Index: 3

Matthew Sample
Matthew Sample

H-Index: 7

Audrone Lapinaite
Audrone Lapinaite

H-Index: 8

Giulia Palermo
Giulia Palermo

H-Index: 22

Folding and unfolding of an alpha-helical lid govern target double-stranded DNA break in Cas12a

Biophysical Journal

2024/2/8

Aakash Saha
Aakash Saha

H-Index: 3

Mohd Ahsan
Mohd Ahsan

H-Index: 3

Giulia Palermo
Giulia Palermo

H-Index: 22

The synchronized catalytic dance of CRISPR-Cas9

Nature Catalysis

2023/10

Aakash Saha
Aakash Saha

H-Index: 3

Giulia Palermo
Giulia Palermo

H-Index: 22

Structure and dynamics of off-target effects in CRISPR-Cas9

Biophysical Journal

2023/2/10

Aakash Saha
Aakash Saha

H-Index: 3

Martin Pacesa
Martin Pacesa

H-Index: 5

Martin Jinek
Martin Jinek

H-Index: 41

Giulia Palermo
Giulia Palermo

H-Index: 22

Key role of an alpha-helical lid in driving the target DNA toward catalysis in CRISPR-Cas12a

Biophysical Journal

2023/2/10

Aakash Saha
Aakash Saha

H-Index: 3

Mohd Ahsan
Mohd Ahsan

H-Index: 3

Michael Schmitz
Michael Schmitz

H-Index: 6

Martin Jinek
Martin Jinek

H-Index: 41

Giulia Palermo
Giulia Palermo

H-Index: 22

GPU-enhanced DFTB metadynamics for efficiently predicting free energies of biochemical systems

Molecules

2023/1/28

Anshuman Kumar
Anshuman Kumar

H-Index: 4

Aakash Saha
Aakash Saha

H-Index: 3

Giulia Palermo
Giulia Palermo

H-Index: 22

Harnessing GPU-Enhanced Simulations for Efficient DFTB Metadynamics of Biochemical Systems

APS March Meeting Abstracts

2023

Anshuman Kumar
Anshuman Kumar

H-Index: 4

Pablo Arantes
Pablo Arantes

H-Index: 5

Aakash Saha
Aakash Saha

H-Index: 3

Giulia Palermo
Giulia Palermo

H-Index: 22

Structural basis for Cas9 off-target activity

Cell

2022/10/27

Martin Pacesa
Martin Pacesa

H-Index: 5

Aakash Saha
Aakash Saha

H-Index: 3

Giulia Palermo
Giulia Palermo

H-Index: 22

Peter Cameron
Peter Cameron

H-Index: 29

Martin Jinek
Martin Jinek

H-Index: 41

Enhancement of CRISPR/Cas12a trans-cleavage activity using hairpin DNA reporters

Nucleic acids research

2022/8/12

Marianna Rossetti
Marianna Rossetti

H-Index: 5

Danila Moscone
Danila Moscone

H-Index: 42

Aakash Saha
Aakash Saha

H-Index: 3

Francesco Ricci
Francesco Ricci

H-Index: 14

John Van Der Oost
John Van Der Oost

H-Index: 55

Giulia Palermo
Giulia Palermo

H-Index: 22

Alessandro Porchetta
Alessandro Porchetta

H-Index: 17

Dynamics and mechanisms of CRISPR-Cas9 through the lens of computational methods

Biophysical Journal

2024/2/8

Giulia Palermo
Giulia Palermo

H-Index: 22

Atomistic understanding of the RNA-mediated allosteric crosstalk in Cas13a

Biophysical Journal

2022/2/11

Aakash Saha
Aakash Saha

H-Index: 3

Giulia Palermo
Giulia Palermo

H-Index: 22

Multi-microsecond molecular dynamics unveils the mechanism of DNA traversal within CRISPR-Cas12a

Biophysical Journal

2022/2/11

Aakash Saha
Aakash Saha

H-Index: 3

Mohd Ahsan
Mohd Ahsan

H-Index: 3

Martin Jinek
Martin Jinek

H-Index: 41

Giulia Palermo
Giulia Palermo

H-Index: 22

Frontiers of metal-coordinating drug design

2021/5/4

Giulia Palermo
Giulia Palermo

H-Index: 22

Angelo Spinello
Angelo Spinello

H-Index: 17

Aakash Saha
Aakash Saha

H-Index: 3

Cover Image, Volume 11, Issue 3.

WIREs: Computational Molecular Science

2021/5/1

Pablo Ricardo Arantes
Pablo Ricardo Arantes

H-Index: 5

Aakash Saha
Aakash Saha

H-Index: 3

Giulia Palermo
Giulia Palermo

H-Index: 22

Establishing the allosteric mechanism in CRISPR‐Cas9

WIREs Computational Molecular Science

2020/10/26

Aakash Saha
Aakash Saha

H-Index: 3

Giulia Palermo
Giulia Palermo

H-Index: 22

Cooperative Dynamics of REC-Nuc Lobes Prime Cas12a for DNA Processing

Biophysical Journal

2021/2/12

Aakash Saha
Aakash Saha

H-Index: 3

Martin Jinek
Martin Jinek

H-Index: 41

Giulia Palermo
Giulia Palermo

H-Index: 22

DNA-Induced Allosteric Control Regulates Activation of Cas12A

Biophysical Journal

2021/2/12

Aakash Saha
Aakash Saha

H-Index: 3

Martin Jinek
Martin Jinek

H-Index: 41

Giulia Palermo
Giulia Palermo

H-Index: 22

Molecular dynamics reveals a DNA-induced dynamic switch triggering activation of CRISPR-Cas12a

Journal of chemical information and modeling

2020/10/27

Aakash Saha
Aakash Saha

H-Index: 3

Martin Jinek
Martin Jinek

H-Index: 41

Giulia Palermo
Giulia Palermo

H-Index: 22

Fighting COVID-19 using molecular dynamics simulations

ACS Central Science

2020/10/12

Aakash Saha
Aakash Saha

H-Index: 3

Giulia Palermo
Giulia Palermo

H-Index: 22

See List of Professors in Aakash Saha University(University of California, Riverside)

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