Aakash Saha
University of California, Riverside
H-index: 7
North America-United States
Top articles of Aakash Saha
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
An alpha-helical lid guides the target DNA toward catalysis in CRISPR-Cas12a | Nature Communications | Aakash Saha Mohd Ahsan Pablo R Arantes Michael Schmitz Christelle Chanez | 2024/2/17 |
Biophysical origin of adenine base editors’ improved editing efficiency | Biophysical Journal | Pablo R Arantes Souvik Sinha Xiaoyu Chen Aakash Saha Amun C Patel | 2024/2/8 |
Folding and unfolding of an alpha-helical lid govern target double-stranded DNA break in Cas12a | Biophysical Journal | Aakash Saha Isabel Strohkendl Mohd Ahsan Catherine Moy Alexander-Hoi Nguyen | 2024/2/8 |
Key role of an alpha-helical lid in driving the target DNA toward catalysis in CRISPR-Cas12a | Biophysical Journal | Aakash Saha Mohd Ahsan Pablo R Arantes Christelle Chanez Michael Schmitz | 2023/2/10 |
GPU-enhanced DFTB metadynamics for efficiently predicting free energies of biochemical systems | Molecules | Anshuman Kumar Pablo R Arantes Aakash Saha Giulia Palermo Bryan M Wong | 2023/1/28 |
Harnessing GPU-Enhanced Simulations for Efficient DFTB Metadynamics of Biochemical Systems | APS March Meeting Abstracts | Anshuman Kumar Pablo Arantes Aakash Saha Giulia Palermo Bryan Wong | 2023 |
The synchronized catalytic dance of CRISPR-Cas9 | Nature Catalysis | Aakash Saha Chinmai Pindi Giulia Palermo | 2023/10 |
Structure and dynamics of off-target effects in CRISPR-Cas9 | Biophysical Journal | Pablo R Arantes Brandon P Mitchell Aakash Saha Lukasz Nierzwicki Martin Pacesa | 2023/2/10 |
Dynamics and mechanisms of CRISPR-Cas9 through the lens of computational methods | Biophysical Journal | Giulia Palermo | 2024/2/8 |
Atomistic understanding of the RNA-mediated allosteric crosstalk in Cas13a | Biophysical Journal | Souvik Sinha Pablo R Arantes Aakash Saha Giulia Palermo | 2022/2/11 |
Multi-microsecond molecular dynamics unveils the mechanism of DNA traversal within CRISPR-Cas12a | Biophysical Journal | Aakash Saha Pablo R Arantes Mohd Ahsan Martin Jinek Giulia Palermo | 2022/2/11 |
Structural basis for Cas9 off-target activity | Cell | Martin Pacesa Chun-Han Lin Antoine Cléry Aakash Saha Pablo R Arantes | 2022/10/27 |
Enhancement of CRISPR/Cas12a trans-cleavage activity using hairpin DNA reporters | Nucleic acids research | Marianna Rossetti Rosa Merlo Neda Bagheri Danila Moscone Anna Valenti | 2022/8/12 |
Establishing the allosteric mechanism in CRISPR‐Cas9 | WIREs Computational Molecular Science | Łukasz Nierzwicki Pablo R. Arantes Aakash Saha Giulia Palermo | 2020/10/26 |
Cooperative Dynamics of REC-Nuc Lobes Prime Cas12a for DNA Processing | Biophysical Journal | Aakash Saha Pablo R Arantes Rohaine Hsu Yogesh B Narkhede Martin Jinek | 2021/2/12 |
DNA-Induced Allosteric Control Regulates Activation of Cas12A | Biophysical Journal | Pablo R Arantes Aakash Saha Martin Jinek Giulia Palermo | 2021/2/12 |
Frontiers of metal-coordinating drug design | Giulia Palermo Angelo Spinello Aakash Saha Alessandra Magistrato | 2021/5/4 | |
Cover Image, Volume 11, Issue 3. | WIREs: Computational Molecular Science | Łukasz Nierzwicki Pablo Ricardo Arantes Aakash Saha Giulia Palermo | 2021/5/1 |
Molecular dynamics reveals a DNA-induced dynamic switch triggering activation of CRISPR-Cas12a | Journal of chemical information and modeling | Aakash Saha Pablo R Arantes Rohaine V Hsu Yogesh B Narkhede Martin Jinek | 2020/10/27 |
Fighting COVID-19 using molecular dynamics simulations | ACS Central Science | Pablo R Arantes Aakash Saha Giulia Palermo | 2020/10/12 |
Co-Authors
