Zhong-Yin Zhang
Purdue University
H-index: 95
North America-United States
Top articles of Zhong-Yin Zhang
Natural product-inspired molecules for covalent inhibition of SHP2 tyrosine phosphatase
Tetrahedron
2024/3/2
Zihan Qu
H-Index: 1
Zhong-Yin Zhang
H-Index: 42
Driving axon regeneration by orchestrating neuronal and non-neuronal innate immune responses via the IFNγ-cGAS-STING axis
Neuron
2023/1/18
Inhibition of PRMT5 by market drugs as a novel cancer therapeutic avenue
Genes & Diseases
2023/1/1
Sesquiterpenoid analogs
2023/11/14
Discovery of a selective TC-PTP degrader for cancer immunotherapy
Chemical Science
2023/10/24
Discovery of a SHP2 Degrader with In Vivo Anti-Tumor Activity
Molecules
2023/10
A small molecule inhibitor of PTP1B and PTPN2 enhances T cell anti-tumor immunity
Nature Communications
2023/7/27
Xin Du
H-Index: 5
Hao Chen
H-Index: 7
Zihan Qu
H-Index: 1
Zhong-Yin Zhang
H-Index: 42
Tony Tiganis
H-Index: 33
Small Molecule Degraders of Protein Tyrosine Phosphatase 1B and T‐Cell Protein Tyrosine Phosphatase for Cancer Immunotherapy
Angewandte Chemie International Edition
2023/5/22
PTP4A2 promotes lysophagy by dephosphorylation of VCP/p97 at Tyr805
Autophagy
2023/5/4
Lymphoid-specific tyrosine phosphatase (LYP) inhibitors
2023/4/18
PRL2 phosphatase enhances oncogenic FLT3 signaling via dephosphorylation of the E3 ubiquitin ligase CBL at tyrosine 371
Blood
2023/1/19
High-throughput screening strategies for space-based radiation countermeasure discovery
2022/11/1
Structure-based design of active-site-directed, highly potent, selective, and orally bioavailable low-molecular-weight protein tyrosine phosphatase inhibitors
Journal of medicinal chemistry
2022/10/5
Jifeng Wang
H-Index: 10
Amy Lin
H-Index: 3
Li Wu
H-Index: 29
Nicholas Noinaj
H-Index: 26
Zhong-Yin Zhang
H-Index: 42
PTPN22: Structure, function, and developments in inhibitor discovery with applications for immunotherapy
2022/8/3
Jianping Lin
H-Index: 19
Zhong-Yin Zhang
H-Index: 42
The Toxoplasma glucan phosphatase TgLaforin utilizes a distinct functional mechanism that can be exploited by therapeutic inhibitors
Journal of Biological Chemistry
2022/7/1
Robert D Murphy
H-Index: 3
Jianping Lin
H-Index: 19
Li Wu
H-Index: 29
Savita Sharma
H-Index: 6
Zhong-Yin Zhang
H-Index: 42
Purification and cryo-EM structure determination of VCP/p97 dodecamers from mammalian and bacterial cells
STAR protocols
2022/6/17
Targeted Covalent Inhibition of Small CTD Phosphatase-1 to Promote the Degradation of REST Transcription Factor in Human Cells
J med chem
2022
N-aryl oxamic acids
2021/12/7
Cryo-electron microscopy structures of VCP/p97 reveal a new mechanism of oligomerization regulation
iScience
2021/11/19
Systemic inhibition of PTPN22 augments anticancer immunity
The Journal of Clinical Investigation
2021/9/1
Jianping Lin
H-Index: 19
Yunpeng Bai
H-Index: 1
Jing He
H-Index: 4
Mark Yarchoan
H-Index: 27
Zhong-Yin Zhang
H-Index: 42