Zhong-Yin Zhang
Purdue University
H-index: 95
North America-United States
Top articles of Zhong-Yin Zhang
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
Natural product-inspired molecules for covalent inhibition of SHP2 tyrosine phosphatase | Tetrahedron | Weida Liang Aaron D Krabill Katelyn S Gallagher Christine Muli Zihan Qu | 2024/3/2 |
Discovery of a selective TC-PTP degrader for cancer immunotherapy | Chemical Science | Zhang ZY Miao J Dong J Miao Y Bai Y Qu Z | 2023/10/24 |
Discovery of a SHP2 Degrader with In Vivo Anti-Tumor Activity | Molecules | Zhang ZY Miao J Bai Y Miao Y Qu Z Dong J | 2023/10 |
PRL2 phosphatase enhances oncogenic FLT3 signaling via dephosphorylation of the E3 ubiquitin ligase CBL at tyrosine 371 | Blood | H Chen Bai Y. et al. | 2023/1/19 |
A small molecule inhibitor of PTP1B and PTPN2 enhances T cell anti-tumor immunity | Nature Communications | Shuwei Liang Eric Tran Xin Du Jiajun Dong Harrison Sudholz | 2023/7/27 |
Driving axon regeneration by orchestrating neuronal and non-neuronal innate immune responses via the IFNγ-cGAS-STING axis | Neuron | Xu Wang Chao Yang Xuejie Wang Jinmin Miao Weitao Chen | 2023/1/18 |
Small Molecule Degraders of Protein Tyrosine Phosphatase 1B and T‐Cell Protein Tyrosine Phosphatase for Cancer Immunotherapy | Angewandte Chemie International Edition | Jiajun Dong Jinmin Miao Yiming Miao Zihan Qu Sheng Zhang | 2023/5/22 |
Inhibition of PRMT5 by market drugs as a novel cancer therapeutic avenue | Genes & Diseases | Lakshmi Prabhu Matthew Martin Lan Chen Özlem Demir Jiamin Jin | 2023/1/1 |
PTP4A2 promotes lysophagy by dephosphorylation of VCP/p97 at Tyr805 | Autophagy | Yunpeng Bai Guimei Yu Hong-Ming Zhou Ovini Amarasinghe Yuan Zhou | 2023/5/4 |
Sesquiterpenoid analogs | 2023/11/14 | ||
Lymphoid-specific tyrosine phosphatase (LYP) inhibitors | 2023/4/18 | ||
Structure-based design of active-site-directed, highly potent, selective, and orally bioavailable low-molecular-weight protein tyrosine phosphatase inhibitors | Journal of medicinal chemistry | Rongjun He Jifeng Wang Zhi-Hong Yu Julie S Moyers M Dodson Michael | 2022/10/5 |
PTPN22: Structure, function, and developments in inhibitor discovery with applications for immunotherapy | Brenson A Jassim Jianping Lin Zhong-Yin Zhang | 2022/8/3 | |
The Toxoplasma glucan phosphatase TgLaforin utilizes a distinct functional mechanism that can be exploited by therapeutic inhibitors | Journal of Biological Chemistry | Robert D Murphy Tiantian Chen Jianping Lin Rongjun He Li Wu | 2022/7/1 |
Purification and cryo-EM structure determination of VCP/p97 dodecamers from mammalian and bacterial cells | STAR protocols | Guimei Yu Yunpeng Bai Zhong-Yin Zhang | 2022/6/17 |
Targeted Covalent Inhibition of Small CTD Phosphatase-1 to Promote the Degradation of REST Transcription Factor in Human Cells | J med chem | B. P Medellin | 2022 |
High-throughput screening strategies for space-based radiation countermeasure discovery | Karson S Putt Yuhong Du Haian Fu Zhong-Yin Zhang | 2022/11/1 | |
The Q61H mutation decouples KRAS from upstream regulation and renders cancer cells resistant to SHP2 inhibitors | Nature communications | Teklab Gebregiworgis Yoshihito Kano Jonathan St-Germain Nikolina Radulovich Molly L Udaskin | 2021/11/1 |
Cryo-electron microscopy structures of VCP/p97 reveal a new mechanism of oligomerization regulation | iScience | 2021 G Yu Y Bai K Li O Amarasinghe W Jiang | 2021/11/19 |
Systemic inhibition of PTPN22 augments anticancer immunity | The Journal of Clinical Investigation | Won Jin Ho Sarah Croessmann Jianping Lin Zaw H Phyo Soren Charmsaz | 2021/9/1 |
Co-Authors
