Zhengqiu Li

About Zhengqiu Li

Zhengqiu Li, With an exceptional h-index of 19 and a recent h-index of 16 (since 2020), a distinguished researcher at Jinan University, specializes in the field of Chemical Biology.

His recent articles reflect a diverse array of research interests and contributions to the field:

Catalyst-free late-stage functionalization to assemble α-acyloxyenamide electrophiles for selectively profiling conserved lysine residues

Novel Covalent Probe Selectively Targeting Glutathione Peroxidase 4 In Vivo: Potential Applications in Pancreatic Cancer Therapy

ENO2-derived phosphoenolpyruvate functions as an endogenous inhibitor of HDAC1 and confers resistance to antiangiogenic therapy

The role of SLC12A family of cation-chloride cotransporters and drug discovery methodologies

Simultaneous covalent modification of K-Ras (G12D) and K-Ras (G12C) with tunable oxirane electrophiles

A fluorogenic-inhibitor-based probe for profiling and imaging of monoamine oxidase A in live human glioma cells and clinical tissues

Ynamide Coupling Reagent for the Chemical Cross-Linking of Proteins in Live Cells

Midbrain dopamine oxidation links ubiquitination of glutathione peroxidase 4 to ferroptosis of dopaminergic neurons

Zhengqiu Li Information

University

Position

___

Citations(all)

1601

Citations(since 2020)

1088

Cited By

943

hIndex(all)

19

hIndex(since 2020)

16

i10Index(all)

22

i10Index(since 2020)

21

Email

University Profile Page

Google Scholar

Zhengqiu Li Skills & Research Interests

Chemical Biology

Top articles of Zhengqiu Li

Catalyst-free late-stage functionalization to assemble α-acyloxyenamide electrophiles for selectively profiling conserved lysine residues

Communications Chemistry

2024/2/14

Novel Covalent Probe Selectively Targeting Glutathione Peroxidase 4 In Vivo: Potential Applications in Pancreatic Cancer Therapy

Journal of Medicinal Chemistry

2024/1/24

ENO2-derived phosphoenolpyruvate functions as an endogenous inhibitor of HDAC1 and confers resistance to antiangiogenic therapy

Nature Metabolism

2023/10

Simultaneous covalent modification of K-Ras (G12D) and K-Ras (G12C) with tunable oxirane electrophiles

Journal of the American Chemical Society

2023/8/3

A fluorogenic-inhibitor-based probe for profiling and imaging of monoamine oxidase A in live human glioma cells and clinical tissues

Science China Chemistry

2023/7

Ynamide Coupling Reagent for the Chemical Cross-Linking of Proteins in Live Cells

ACS Chemical Biology

2023/5/26

Midbrain dopamine oxidation links ubiquitination of glutathione peroxidase 4 to ferroptosis of dopaminergic neurons

The Journal of clinical investigation

2023/5/15

Affinity-based protein profiling-driven discovery of myricanol as a Nampt activator

Bioorganic Chemistry

2023/4/1

Cyclopropenone, Cyclopropeniminium Ion, and Cyclopropenethione as Novel Electrophilic Warheads for Potential Target Discovery of Triple-Negative Breast Cancer

Journal of Medicinal Chemistry

2023/2/10

Blockade of NMT1 enzymatic activity inhibits N-myristoylation of VILIP3 protein and suppresses liver cancer progression

Signal Transduction and Targeted Therapy

2023/1/9

Oxidant-induced bioconjugation for protein labeling in live cells

ACS Chemical Biology

2022/12/21

Comparison of Different Competitive Proteome Profiling Approaches in Target Identification of Covalent Inhibitors

ChemBioChem

2022/12/16

A toxin-deformation dependent inhibition mechanism in the T7SS toxin-antitoxin system of Gram-positive bacteria

Nature Communications

2022/10/28

Ynamide electrophile for the profiling of ligandable carboxyl residues in live cells and the development of new covalent inhibitors

Journal of Medicinal Chemistry

2022/7/26

Discovery of Hexahydrofuro[3,2-b]furans as New Kinase-Selective and Orally Bioavailable JAK3 Inhibitors for the Treatment of Leukemia Harboring a JAK3 …

Journal of Medicinal Chemistry

2022/7/21

Two-photon fluorescent turn-on probes for highly efficient detection and profiling of thiols in live cells and tissues

Biological Chemistry

2022/3/28

Proteome-wide Identification of Off-Targets of a Potent EGFRL858R/T790M Mutant Inhibitor

ACS Medicinal Chemistry Letters

2022/1/19

Novel Electrophilic Warhead Targeting a Triple-Negative Breast Cancer Driver in Live Cells Revealed by “Inverse Drug Discovery”

Journal of Medicinal Chemistry

2021/10/8

Development and application of novel electrophilic warheads in target identification and drug discovery

2021/8/1

See List of Professors in Zhengqiu Li University(Jinan University)