Yu-Chiang Lai

Yu-Chiang Lai

University of Birmingham

H-index: 25

Europe-United Kingdom

About Yu-Chiang Lai

Yu-Chiang Lai, With an exceptional h-index of 25 and a recent h-index of 21 (since 2020), a distinguished researcher at University of Birmingham, specializes in the field of Ubiquitylation and phosphorylation, molecular physiology and biochemistry.

His recent articles reflect a diverse array of research interests and contributions to the field:

Uncovering the mechanisms of MuRF1-induced ubiquitylation and revealing similarities with MuRF2 and MuRF3

The Mechanisms of MuRF1 Ubiquitylation

Postexercise muscle glycogen synthesis with glucose, galactose, and combined galactose-glucose ingestion

–Therapeutic glucocorticoids prevent bone loss but drive muscle wasting when administered in chronic polyarthritis

Ubiquitin E3 ligase Atrogin-1 protein is regulated via the rapamycin-sensitive mTOR-S6K1 signaling pathway in C2C12 muscle cells

The Role of UBE2-Conjugating Enzymes in the Mechanism of MuRF1 Ubiquitylation

Exercise mediates ubiquitin signalling in human skeletal muscle

The effect of ex vivo human serum from liver disease patients on cellular protein synthesis and growth

Yu-Chiang Lai Information

University

Position

___

Citations(all)

2641

Citations(since 2020)

1551

Cited By

1602

hIndex(all)

25

hIndex(since 2020)

21

i10Index(all)

31

i10Index(since 2020)

24

Email

University Profile Page

Google Scholar

Yu-Chiang Lai Skills & Research Interests

Ubiquitylation and phosphorylation

molecular physiology and biochemistry

Top articles of Yu-Chiang Lai

Title

Journal

Author(s)

Publication Date

Uncovering the mechanisms of MuRF1-induced ubiquitylation and revealing similarities with MuRF2 and MuRF3

Biochemistry and Biophysics Reports

Samuel O Lord

Peter WJ Dawson

Jitpisute Chunthorng-Orn

Jimi Ng

Leslie M Baehr

...

2024/3/1

The Mechanisms of MuRF1 Ubiquitylation

Peter WJ Dawson

Jimi Ng

Yu-Chiang Lai

2023/11

Postexercise muscle glycogen synthesis with glucose, galactose, and combined galactose-glucose ingestion

American Journal of Physiology-Endocrinology and Metabolism

Tim Podlogar

Brandon J Shad

Alex P Seabright

Oliver J Odell

Samuel O Lord

...

2023/12/1

–Therapeutic glucocorticoids prevent bone loss but drive muscle wasting when administered in chronic polyarthritis

The role of pre-receptor glucocorticoid metabolism in chronic inflammatory disease-associated muscle atrophy

JM Webster

CG Fenton

CS Martin

S Fareed

C Wehmeyer

...

2022

Ubiquitin E3 ligase Atrogin-1 protein is regulated via the rapamycin-sensitive mTOR-S6K1 signaling pathway in C2C12 muscle cells

American Journal of Physiology-Cell Physiology

Yusuke Nishimura

Jitpisute Chunthorng-Orn

Samuel Lord

Ibrahim Musa

Peter Dawson

...

2022/7/1

The Role of UBE2-Conjugating Enzymes in the Mechanism of MuRF1 Ubiquitylation

bioRxiv

Peter WJ Dawson

Leslie M Baehr

David C Hughes

Timothy J Knowles

Pooja Sridhar

...

2022/6/13

Exercise mediates ubiquitin signalling in human skeletal muscle

FASEB BioAdvances

Samuel O Lord

Yu‐Chiang Lai

2022/6

The effect of ex vivo human serum from liver disease patients on cellular protein synthesis and growth

Cells

Sophie L Allen

Alex P Seabright

Jonathan I Quinlan

Amritpal Dhaliwal

Felicity R Williams

...

2022/3/24

PDX1LOW MAFALOW β-cells contribute to islet function and insulin release

Nature communications

Daniela Nasteska

Nicholas HF Fine

Fiona B Ashford

Federica Cuozzo

Katrina Viloria

...

2021/1/29

Ubiquitin E3 ligases Atrogin-1 and MuRF1 protein contents are differentially regulated in the rapamycin-sensitive mTOR-S6K1 signaling pathway in C2C12 myotubes

Yusuke Nishimura

Ibrahim Musa

Peter Dawson

Lars Holm

Yu-Chiang Lai

2021/10/15

Recent advances in measuring and understanding the regulation of exercise-mediated protein degradation in skeletal muscle

Yusuke Nishimura

Ibrahim Musa

Lars Holm

Yu-Chiang Lai

2021/8/1

Global deletion of 11β-HSD1 prevents muscle wasting associated with glucocorticoid therapy in polyarthritis

International Journal of Molecular Sciences

JM Webster

CG Sagmeister

MS: Fenton

AP Seabright

L Yu-Chiang

...

2021/7/16

In vitro skeletal muscle cell atrophy and mitochondrial dysfunction after exposure to human serum from patients with ESLD and NAFLD

Sophie Allen

Alex Seabright

Jonathan Quinlan

Amritpal Dhaliwal

Felicity Williams

...

2021/7/1

Regulatory roles of PINK1-parkin and AMPK in ubiquitin-dependent skeletal muscle mitophagy

Alex P Seabright

Yu-Chiang Lai

2020/12/3

Mature and immature β-cells both contribute to islet function and insulin release

Daniela Nasteska

Nicholas Fine

Fiona Ashford

Federica Cuozzo

Katrina Viloria

...

2020/7/21

PINK1-dependent phosphorylation of Serine111 within the SF3 motif of Rab GTPases impairs effector interactions and LRRK2-mediated phosphorylation at Threonine72

Biochemical Journal

Sophie Vieweg

Katie Mulholland

Bastian Bräuning

Nitin Kachariya

Yu-Chiang Lai

...

2020/5/15

AMPK activation induces mitophagy and promotes mitochondrial fission while activating TBK1 in a PINK1‐Parkin independent manner

The FASEB Journal

Alex P Seabright

Nicholas HF Fine

Jonathan P Barlow

Samuel O Lord

Ibrahim Musa

...

2020/5

See List of Professors in Yu-Chiang Lai University(University of Birmingham)