Xin He

Xin He

University of Chicago

H-index: 32

North America-United States

About Xin He

Xin He, With an exceptional h-index of 32 and a recent h-index of 22 (since 2020), a distinguished researcher at University of Chicago, specializes in the field of Bioinformatics and Computational Biology, Statistical Genetics, Comparative Genomics.

His recent articles reflect a diverse array of research interests and contributions to the field:

Multiple genes in a single GWAS risk locus synergistically mediate aberrant synaptic development and function in human neurons

Single-cell genomics improves the discovery of risk variants and genes of atrial fibrillation

Single-cell long-read sequencing in human cerebral organoids uncovers cell-type-specific and autism-associated exons

A new Bayesian factor analysis method improves detection of genes and biological processes affected by perturbations in single-cell CRISPR screening

Integration of multi-omics data reveals cis-regulatory variants that are associated with phenotypic differentiation of eastern from western pigs

Annotating functional effects of non-coding variants in neuropsychiatric cell types by deep transfer learning

A functional genomics pipeline identifies pleiotropy and cross-tissue effects within obesity-associated GWAS loci

DECO: a framework for jointly analyzing de novo and rare case/control variants, and biological pathways

Xin He Information

University

Position

Department of Human Genetics

Citations(all)

8307

Citations(since 2020)

4972

Cited By

5495

hIndex(all)

32

hIndex(since 2020)

22

i10Index(all)

41

i10Index(since 2020)

27

Email

University Profile Page

University of Chicago

Google Scholar

View Google Scholar Profile

Xin He Skills & Research Interests

Bioinformatics and Computational Biology

Statistical Genetics

Comparative Genomics

Top articles of Xin He

Title

Journal

Author(s)

Publication Date

Multiple genes in a single GWAS risk locus synergistically mediate aberrant synaptic development and function in human neurons

Cell genomics

Siwei Zhang

Hanwen Zhang

Marc P Forrest

Yifan Zhou

Xiaotong Sun

...

2023/9/13

Single-cell genomics improves the discovery of risk variants and genes of atrial fibrillation

Nature Communications

Alan Selewa

Kaixuan Luo

Michael Wasney

Linsin Smith

Xiaotong Sun

...

2023/8/17

Single-cell long-read sequencing in human cerebral organoids uncovers cell-type-specific and autism-associated exons

Cell reports

Yalan Yang

Runwei Yang

Bowei Kang

Sheng Qian

Xin He

...

2023/11/28

A new Bayesian factor analysis method improves detection of genes and biological processes affected by perturbations in single-cell CRISPR screening

Nature Methods

Yifan Zhou

Kaixuan Luo

Lifan Liang

Mengjie Chen

Xin He

2023/11

Integration of multi-omics data reveals cis-regulatory variants that are associated with phenotypic differentiation of eastern from western pigs

Genetics Selection Evolution

Yuwen Liu

Yang Fu

Yalan Yang

Guoqiang Yi

Jinmin Lian

...

2022/9/14

Annotating functional effects of non-coding variants in neuropsychiatric cell types by deep transfer learning

PLOS Computational Biology

Boqiao Lai

Sheng Qian

Hanwei Zhang

Siwei Zhang

Alena Kozlova

...

2022/5/16

A functional genomics pipeline identifies pleiotropy and cross-tissue effects within obesity-associated GWAS loci

Nature communications

Amelia C Joslin

Débora R Sobreira

Grace T Hansen

Noboru J Sakabe

Ivy Aneas

...

2021/9/6

DECO: a framework for jointly analyzing de novo and rare case/control variants, and biological pathways

Briefings in bioinformatics

Tan-Hoang Nguyen

Xin He

Ruth C Brown

Bradley T Webb

Kenneth S Kendler

...

2021/9

CCmed: cross-condition mediation analysis for identifying replicable trans-associations mediated by cis-gene expression

Bioinformatics

Fan Yang

Kevin J Gleason

Jiebiao Wang

Jubao Duan

Xin He

...

2021/9/1

Allele-specific open chromatin in human iPSC neurons elucidates functional disease variants

Science

Siwei Zhang

Hanwen Zhang

Yifan Zhou

Min Qiao

Siming Zhao

...

2020/7/31

mTADA is a framework for identifying risk genes from de novo mutations in multiple traits

Nature Communications

Tan-Hoang Nguyen

Amanda Dobbyn

Ruth C Brown

Brien P Riley

Joseph D Buxbaum

...

2020/6/10

Mendelian randomization accounting for correlated and uncorrelated pleiotropic effects using genome-wide summary statistics

Nature genetics

Jean Morrison

Nicholas Knoblauch

Joseph H Marcus

Matthew Stephens

Xin He

2020/7/2

Transcriptome and regulatory maps of decidua-derived stromal cells inform gene discovery in preterm birth

Science advances

Noboru J Sakabe

Ivy Aneas

Nicholas Knoblauch

Debora R Sobreira

Nicole Clark

...

2020/12/2

Primo: integration of multiple GWAS and omics QTL summary statistics for elucidation of molecular mechanisms of trait-associated SNPs and detection of pleiotropy in complex traits

Genome biology

Kevin J Gleason

Fan Yang

Brandon L Pierce

Xin He

Lin S Chen

2020/12

Genetic analyses support the contribution of mRNA N 6-methyladenosine (m 6 A) modification to human disease heritability

Nature genetics

Zijie Zhang

Kaixuan Luo

Zhongyu Zou

Maguanyun Qiu

Jiakun Tian

...

2020/9

See List of Professors in Xin He University(University of Chicago)