Xiao-chen Bai

Xiao-chen Bai

University of Texas Southwestern Medical Center

H-index: 47

North America-United States

About Xiao-chen Bai

Xiao-chen Bai, With an exceptional h-index of 47 and a recent h-index of 43 (since 2020), a distinguished researcher at University of Texas Southwestern Medical Center, specializes in the field of Cryo-EM, Structural biology, Receptors.

His recent articles reflect a diverse array of research interests and contributions to the field:

Activation of the insulin receptor by insulin-like growth factor 2

Activation of human STING by a molecular glue-like compound

Applications of cryo-EM in drug development for STING

Challenges and opportunities in macromolecular structure determination

Inhibition of FAM46/TENT5 activity by BCCIPα adopting a unique fold

CTCF and R-loops are boundaries of cohesin-mediated DNA looping

Oncogenic RAS drives resistance to pemigatinib in cholangiocarcinoma harboring a FGFR2 delins disrupting ligand binding

The activation mechanism of the insulin receptor: a structural perspective

Xiao-chen Bai Information

University

Position

___

Citations(all)

12254

Citations(since 2020)

8039

Cited By

7237

hIndex(all)

47

hIndex(since 2020)

43

i10Index(all)

64

i10Index(since 2020)

63

Email

University Profile Page

University of Texas Southwestern Medical Center

Google Scholar

View Google Scholar Profile

Xiao-chen Bai Skills & Research Interests

Cryo-EM

Structural biology

Receptors

Top articles of Xiao-chen Bai

Title

Journal

Author(s)

Publication Date

Activation of the insulin receptor by insulin-like growth factor 2

Nature Communications

Weidong An#

Catherine Hall#

Jie Li

Albert Hung

Jiayi Wu

...

2024/3/23

Activation of human STING by a molecular glue-like compound

Nature chemical biology

Jie Li

Stephen M Canham

Hua Wu

Martin Henault

Lihao Chen

...

2024/3

Applications of cryo-EM in drug development for STING

Xiao-chen Bai

Xuewu Zhang

2024/2/1

Challenges and opportunities in macromolecular structure determination

Xiao-chen Bai

Tamir Gonen

Angela M Gronenborn

Anastassis Perrakis

Andrea Thorn

...

2024/1

Inhibition of FAM46/TENT5 activity by BCCIPα adopting a unique fold

Science Advances

Shun Liu

Hua Chen

Yan Yin

Defen Lu

Guoming Gao

...

2023/4/5

CTCF and R-loops are boundaries of cohesin-mediated DNA looping

Molecular cell

Hongshan Zhang

Zhubing Shi

Edward J Banigan

Yoori Kim

Hongtao Yu

...

2023/8/17

Oncogenic RAS drives resistance to pemigatinib in cholangiocarcinoma harboring a FGFR2 delins disrupting ligand binding

JCO Precision Oncology

Mir Lim

Patrick T Lynch

Xiaochen Bai

David Hsiehchen

2023/1

The activation mechanism of the insulin receptor: a structural perspective

Eunhee Choi

Xiao-Chen Bai

2023/6/20

Structural insights into the assembly of the agrin/LRP4/MuSK signaling complex

Proceedings of the National Academy of Sciences

Tian Xie

Guangjun Xu

Yun Liu

Bradley Quade

Weichun Lin

...

2023/6/6

Structural basis of the alkaline pH-dependent activation of insulin receptor-related receptor

Nature structural & molecular biology

Liwei Wang

Catherine Hall

Jie Li

Eunhee Choi

Xiao-chen Bai

2023/5

Sensory specializations drive octopus and squid behaviour

Nature

Guipeun Kang

Corey AH Allard

Wendy A Valencia-Montoya

Lena van Giesen

Jeong Joo Kim

...

2023/4/13

Structural basis of insulin fibrillation

Science Advances

Liwei Wang

Catherine E Hall

Emiko Uchikawa

Dailu Chen

Eunhee Choi

...

2023/9/15

An antibody that neutralizes SARS-CoV-1 and SARS-CoV-2 by binding to a conserved spike epitope outside the receptor binding motif

Science immunology

Yan Fang

Pengcheng Sun

Xuping Xie

Mingjian Du

Fenghe Du

...

2022/8/4

Synergistic activation of the insulin receptor via two distinct sites

Nature structural & molecular biology

Jie Li

Junhee Park

John P Mayer

Kristofor J Webb

Emiko Uchikawa

...

2022/4

SNARE assembly enlightened by cryo-EM structures of a synaptobrevin–Munc18-1–syntaxin-1 complex

Science advances

Karolina P Stepien

Junjie Xu

Xuewu Zhang

Xiao-Chen Bai

Josep Rizo

2022/6/22

Molecular basis for the role of disulfide-linked αCTs in the activation of insulin-like growth factor 1 receptor and insulin receptor

Elife

Jie Li

Jiayi Wu

Catherine Hall

Xiao-chen Bai

Eunhee Choi

2022/11/22

Cryo-electron microscopic analysis of single-pass transmembrane receptors

Kai Cai

Xuewu Zhang

Xiao-chen Bai

2022/6/17

Activation of the insulin receptor by an insulin mimetic peptide

Nature communications

Junhee Park

Jie Li

John P Mayer

Kerri A Ball

Jiayi Wu

...

2022/9/23

Molecular mechanism of the wake-promoting agent TAK-925

Nature communications

Jie Yin

Yanyong Kang

Aaron P McGrath

Karen Chapman

Megan Sjodt

...

2022/5/25

Structural basis for gating mechanism of the human sodium-potassium pump

Nature communications

Phong T Nguyen

Christine Deisl

Michael Fine

Trevor S Tippetts

Emiko Uchikawa

...

2022/9/8

See List of Professors in Xiao-chen Bai University(University of Texas Southwestern Medical Center)

Co-Authors

H-index: 123
Yigong Shi

Yigong Shi

Tsinghua University

H-index: 85
Venki Ramakrishnan

Venki Ramakrishnan

University of Cambridge

H-index: 78
Sjors Scheres

Sjors Scheres

University of Cambridge

H-index: 32
Alan Brown

Alan Brown

Harvard University

H-index: 23
Leifu Chang

Leifu Chang

Purdue University

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