William M. Shafer

William M. Shafer

Emory & Henry College

H-index: 66

North America-United States

About William M. Shafer

William M. Shafer, With an exceptional h-index of 66 and a recent h-index of 35 (since 2020), a distinguished researcher at Emory & Henry College, specializes in the field of Microbiology.

His recent articles reflect a diverse array of research interests and contributions to the field:

A laboratory-based predictive pathway for the development of Neisseria gonorrhoeae high-level resistance to corallopyronin A, an inhibitor of bacterial RNA …

Ensuring a sustained workforce to combat antibiotic resistance in the 21st century: the critical need for training the next-gen of scientists at the pre-doctoral level

Hormonal steroids induce multidrug resistance and stress response genes in Neisseria gonorrhoeae by binding to MtrR

High-level in vitro resistance to gentamicin acquired in a stepwise manner in Neisseria gonorrhoeae

Neisseria gonorrhoeae MtrCDE Efflux Pump During In Vivo Experimental Genital Tract Infection in Men and Mice Reveals the Presence of Within-Host Colonization Bottleneck

Hormonal steroids bind the Neisseria gonorrhoeae multidrug resistance regulator, MtrR, to induce a multidrug binding efflux pump and stress-response sigma factor

Transcriptional activation of ompA in Neisseria gonorrhoeae mediated by the XRE family member protein NceR

Transcriptional regulation of the mtrCDE efflux pump operon: importance for Neisseria gonorrhoeae antimicrobial resistance

William M. Shafer Information

University

Position

Professor of Microbiology and Immunology School of Medicine

Citations(all)

14416

Citations(since 2020)

4544

Cited By

11611

hIndex(all)

66

hIndex(since 2020)

35

i10Index(all)

168

i10Index(since 2020)

93

Email

University Profile Page

Emory & Henry College

Google Scholar

View Google Scholar Profile

William M. Shafer Skills & Research Interests

Microbiology

Top articles of William M. Shafer

Title

Journal

Author(s)

Publication Date

A laboratory-based predictive pathway for the development of Neisseria gonorrhoeae high-level resistance to corallopyronin A, an inhibitor of bacterial RNA …

Microbiology Spectrum

Jacqueline T Balthazar

Daniel Golparian

Magnus Unemo

Timothy D Read

Miriam Grosse

...

2024/4/22

Ensuring a sustained workforce to combat antibiotic resistance in the 21st century: the critical need for training the next-gen of scientists at the pre-doctoral level

Antimicrobial Agents and Chemotherapy

William M Shafer

Graeme L Conn

2024/4/19

Hormonal steroids induce multidrug resistance and stress response genes in Neisseria gonorrhoeae by binding to MtrR

Nature Communications

Grace M Hooks

Julio C Ayala

Concerta L Holley

Vijaya Dhulipala

Grace A Beggs

...

2024/2/7

High-level in vitro resistance to gentamicin acquired in a stepwise manner in Neisseria gonorrhoeae

Journal of Antimicrobial Chemotherapy

Daniel Golparian

Susanne Jacobsson

Concerta L Holley

William M Shafer

Magnus Unemo

2023/7

Neisseria gonorrhoeae MtrCDE Efflux Pump During In Vivo Experimental Genital Tract Infection in Men and Mice Reveals the Presence of Within-Host Colonization Bottleneck

medRxiv

Andreea Waltmann

Jacqueline T Balthazar

Afrin A Begum

Nancy Hua

Ann E Jerse

...

2023

Hormonal steroids bind the Neisseria gonorrhoeae multidrug resistance regulator, MtrR, to induce a multidrug binding efflux pump and stress-response sigma factor

bioRxiv

Grace Hooks

Julio Ayala

Grace Beggs

John R Perfect

Maria Schumacher

...

2023

Transcriptional activation of ompA in Neisseria gonorrhoeae mediated by the XRE family member protein NceR

Mbio

Concerta L Holley

Vijaya Dhulipala

Stavaros A Maurakis

Ashley Nicole Greenawalt

Timothy D Read

...

2023/8/31

Transcriptional regulation of the mtrCDE efflux pump operon: importance for Neisseria gonorrhoeae antimicrobial resistance

Julio C Ayala

Jacqueline T Balthazar

William M Shafer

2022/8/2

A Single Amino Acid Substitution in Elongation Factor G Can Confer Low-Level Gentamicin Resistance in Neisseria gonorrhoeae

Antimicrobial Agents and Chemotherapy

Concerta L Holley

Vijaya Dhulipala

Jacqueline T Balthazar

Adriana Le Van

Afrin A Begum

...

2022/5/17

Gonococcal Clinical Strains Bearing a Common gdhR Single Nucleotide Polymorphism That Results in Enhanced Expression of the Virulence Gene lctP Frequently Possess …

Mbio

Julio C Ayala

Matthew W Schmerer

Ellen N Kersh

Magnus Unemo

William M Shafer

2022/4/26

Structural basis of peptide-based antimicrobial inhibition of a resistance-nodulation-cell division multidrug efflux pump

Microbiology Spectrum

Meinan Lyu

Julio C Ayala

Isabella Chirakos

Chih-Chia Su

William M Shafer

...

2022/10/26

Potent In Vitro and Ex Vivo Anti-Gonococcal Activity of the RpoB Inhibitor Corallopyronin A

Msphere

Jennifer L Edwards

Jacqueline T Balthazar

Danillo LA Esposito

Julio C Ayala

Andrea Schiefer

...

2022/10/26

Additional file 2 of A community-driven resource for genomic epidemiology and antimicrobial resistance prediction of Neisseria gonorrhoeae at Pathogenwatch

David M Aanensen

Khalil Abudahab

Silvia Argimón

Michelle J Cole

Richard J Goater

...

2021

A community-driven resource for genomic epidemiology and antimicrobial resistance prediction of Neisseria gonorrhoeae at Pathogenwatch

Genome medicine

Leonor Sánchez-Busó

Corin A Yeats

Benjamin Taylor

Richard J Goater

Anthony Underwood

...

2021/12

Structures of Neisseria gonorrhoeae MtrR-operator complexes reveal molecular mechanisms of DNA recognition and antibiotic resistance-conferring clinical …

Nucleic Acids Research

Grace A Beggs

Julio C Ayala

Logan G Kavanaugh

Timothy D Read

Grace M Hooks

...

2021/4/19

Identification of a Histone Deacetylase: Epigenetic Impact on Host Gene Expression.

Susu M Zughaier

Corinne E Rouquette-Loughlin

William M Shafer

2020/2/1

Azithromycin susceptibility of Neisseria gonorrhoeae in the USA in 2017: a genomic analysis of surveillance data

The Lancet Microbe

Kim M Gernert

Sandra Seby

Matthew W Schmerer

Jesse C Thomas

Cau D Pham

...

2020/8/1

The serogroup B meningococcal outer membrane vesicle-based vaccine 4CMenB induces cross-species protection against Neisseria gonorrhoeae

PLoS Pathogens

Isabelle Leduc

Kristie L Connolly

Afrin Begum

Knashka Underwood

Stephen Darnell

...

2020/12/8

Cryo-EM structures of a gonococcal multidrug efflux pump illuminate a mechanism of drug recognition and resistance

Mbio

Meinan Lyu

Mitchell A Moseng

Jennifer L Reimche

Concerta L Holley

Vijaya Dhulipala

...

2020/6/30

Genomic evolution of Neisseria gonorrhoeae since the preantibiotic era (1928–2013): antimicrobial use/misuse selects for resistance and drives evolution

BMC genomics

Daniel Golparian

Simon R Harris

Leonor Sánchez-Busó

Steen Hoffmann

William M Shafer

...

2020/12

See List of Professors in William M. Shafer University(Emory & Henry College)