William Gmeiner

William Gmeiner

Wake Forest University

H-index: 32

North America-United States

About William Gmeiner

William Gmeiner, With an exceptional h-index of 32 and a recent h-index of 18 (since 2020), a distinguished researcher at Wake Forest University, specializes in the field of Cancer Biology, DNA therapeutics, F10, aptamers, zinc.

His recent articles reflect a diverse array of research interests and contributions to the field:

The effect of tumor microenvironment and thymidylate synthase expression levels on growth and metastasis of colorectal cancer

Enhanced Therapeutic Efficacy of the Nanoscale Fluoropyrimidine Polymer CF10 in a Rat Colorectal Cancer Liver Metastasis Model

Role of O-GlcNAc conjugation and TS translational repression in 5-FU/LV resistance in CRC and CF10 response

Recent Advances in Therapeutic Strategies to Improve Colorectal Cancer Treatment

Review of 5-FU resistance mechanisms in colorectal cancer: Clinical significance of attenuated on-target effects

Thymidylate Synthase Inhibition with Capped F10 Is Effective in TP53 Null Acute Myeloid Leukemia (AML)

Capped F10, a novel DNA directed fluoropyrimidine, in TP53 mutated acute myeloid leukemia (AML).

A novel fluoropyrimidine drug to treat recalcitrant colorectal cancer

William Gmeiner Information

University

Position

Wake Forest School of Medicine

Citations(all)

4386

Citations(since 2020)

1356

Cited By

3541

hIndex(all)

32

hIndex(since 2020)

18

i10Index(all)

94

i10Index(since 2020)

34

Email

University Profile Page

Wake Forest University

Google Scholar

View Google Scholar Profile

William Gmeiner Skills & Research Interests

Cancer Biology

DNA therapeutics

F10

aptamers

zinc

Top articles of William Gmeiner

Title

Journal

Author(s)

Publication Date

The effect of tumor microenvironment and thymidylate synthase expression levels on growth and metastasis of colorectal cancer

The American Journal of the Medical Sciences

A Balarajan

A Ray

X Zhang

G Maresh

Z Deng

...

2024/2/1

Enhanced Therapeutic Efficacy of the Nanoscale Fluoropyrimidine Polymer CF10 in a Rat Colorectal Cancer Liver Metastasis Model

Cancers

Charles Chidi Okechukwu

Xue Ma

Naresh Sah

Chinnadurai Mani

Komaraiah Palle

...

2024/3/30

Role of O-GlcNAc conjugation and TS translational repression in 5-FU/LV resistance in CRC and CF10 response

Cancer Research

Charles C Okechukwu

Xue Ma

William H Gmeiner

2024/3/22

Recent Advances in Therapeutic Strategies to Improve Colorectal Cancer Treatment

William H Gmeiner

2024/3/2

Review of 5-FU resistance mechanisms in colorectal cancer: Clinical significance of attenuated on-target effects

William H Gmeiner

Charles Chidi Okechukwu

2023

Thymidylate Synthase Inhibition with Capped F10 Is Effective in TP53 Null Acute Myeloid Leukemia (AML)

Blood

Charles Okechukwu

Kristin Pladna

William Gmeiner

Timothy Pardee

2023/11/28

Capped F10, a novel DNA directed fluoropyrimidine, in TP53 mutated acute myeloid leukemia (AML).

Timothy S Pardee

Charles Okechukwu

Kristin Pladna

William Gmeiner

2023/6/1

A novel fluoropyrimidine drug to treat recalcitrant colorectal cancer

Naresh Sah

Pamela Luna

Chinnadurai Mani

William Gmeiner

Komaraiah Palle

2023/6/1

A novel second-generation nano-fluoropyrimidine to treat metastatic colorectal cancer and overcome 5-fluorouracil resistance

Cancer Research

Naresh Sah

Pamela Luna

Chinnadurai Mani

William Gmeiner

Komaraiah Palle

2023/4/4

Reducing Colorectal Cancer Mortality with CF10

William H Gmeiner

2022/10/1

The polymeric fluoropyrimidine CF10 overcomes limitations of 5-FU in pancreatic ductal adenocarcinoma cells through increased replication stress

Cancer Research

Roberto DiNiro

Alex O Haber

Kang J Jeong

Soon Y Park

Gordon B Mills

...

2022/6/15

TP53 knockout in MCF7 breast cancer cells induces sensitivity to fluoropyrimidine drugs

bioRxiv

JM Warrington

S Mehta

VF Moy

JR Patel

C Liu

...

2022/2/11

Cytotoxic fluoropyrimidine polymers and methods of use thereof

2021/7/15

AraC-FdUMP[10] Is a Next-Generation Fluoropyrimidine with Potent Antitumor Activity in PDAC and Synergy with PARG Inhibition

Molecular Cancer Research

Alex O Haber

Aditi Jain

Chinnadurai Mani

Avinoam Nevler

Lebaron C Agostini

...

2021/4/1

Recent advances in our knowledge of mCRC tumor biology and genetics: a focus on targeted therapy development

William H Gmeiner

2021/3/25

Improved antitumor activity of the fluoropyrimidine polymer CF10 in preclinical colorectal cancer models through distinct mechanistic and pharmacologic properties

Molecular cancer therapeutics

William H Gmeiner

Anthony Dominijanni

Alex O Haber

Lais P Ghiraldeli

David L Caudell

...

2021/3/1

Targeting DNA topoisomerases: past & future

Cancer Drug Resistance

William H Gmeiner

Robert CAM van Waardenburg

2021

A narrative review of genetic factors affecting fluoropyrimidine toxicity

William H Gmeiner

2021/12

Hairpin Oligonucleotide Can Functionalize Gold Nanorods for in Vivo Application Delivering Cytotoxic Nucleotides and Curcumin: A Comprehensive Study in …

ACS omega

Upasana Das

Avishek Bhuniya

Anup K Roy

William H Gmeiner

Supratim Ghosh

2020/11/2

Development of a colorectal cancer 3D micro-tumor construct platform from cell lines and patient tumor biospecimens for standard-of-care and experimental drug screening

Annals of biomedical engineering

Steven Forsythe

Naren Mehta

Mahesh Devarasetty

Hemamylammal Sivakumar

William Gmeiner

...

2020/3

See List of Professors in William Gmeiner University(Wake Forest University)