William DeGrado
University of California, San Francisco
H-index: 132
North America-United States
Top articles of William DeGrado
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
De novo-designed transmembrane proteins bind and regulate a cytokine receptor | Nature Chemical Biology | Marco Mravic Li He Huong T Kratochvil Hailin Hu Sarah E Nick | 2024/3/13 |
An enhanced broad-spectrum peptide inhibits Omicron variants in vivo | Cell Reports Medicine | Wenwen Bi Kaiming Tang Guilin Chen Yubin Xie Nicholas F Polizzi | 2024/2/9 |
Docking for molecules that bind in a symmetric stack to Alzheimer’s disease tau fibrils with SymDOCK | Biophysical Journal | Matthew S Smith Peter Kunach Ian S Knight Rian Kormos Joseph G Pepe | 2024/2/8 |
IL-13 and IL-17A Activate β1 Integrins Through an NF-κB/Rho Kinase/PIP5K1γ Pathway to Enhance Force Transmission in Airway Smooth Muscle | Uyen Ngo Ying Shi AR Charbit JV Fahy P Woodruff | 2024/5 | |
De novo Design of Peptides that Bind Specific Conformers of α-Synuclein | Chemical Science | Hailey M Wallace Hyunjun Yang Sophia K Tan Henry S Pan Rose Yang | 2024 |
Suggested searches | Perspective | Sunkyung Kim Jing Chen Feiya Ou Tian-Tian Liu Suin Jo | 2024/3/4 |
De novo design of drug-binding proteins with predictable binding energy and specificity | Science | Lei Lu Xuxu Gou Sophia K Tan Samuel I Mann Hyunjun Yang | 2024/4/5 |
Designed proteins for ligand binding | 2023/8/10 | ||
A host defense peptide mimetic, brilacidin, potentiates caspofungin antifungal activity against human pathogenic fungi | Nature communications | Thaila Fernanda Dos Reis Patrícia Alves De Castro Rafael Wesley Bastos Camila Figueiredo Pinzan Pedro FN Souza | 2023/4/12 |
Transient water wires mediate selective proton transport in designed channel proteins | Nature chemistry | Huong T Kratochvil Laura C Watkins Marco Mravic Jessica L Thomaston John M Nicoludis | 2023/7 |
EMBER multidimensional spectral microscopy enables quantitative determination of disease-and cell-specific amyloid strains | Proceedings of the National Academy of Sciences | Hyunjun Yang Peng Yuan Yibing Wu Marie Shi Christoffer D Caro | 2023/3/21 |
Patterning and folding of intestinal villi by active mesenchymal dewetting | bioRxiv | Tyler R Huycke Hikaru Miyazaki Teemu J Häkkinen Vasudha Srivastava Emilie Barruet | 2023/6/26 |
Inhibitors of integrin alpha 2 beta 1 and methods of use | 2023/3/7 | ||
Stacked binding of a PET ligand to Alzheimer’s tau paired helical filaments | Nature communications | Gregory E Merz Matthew J Chalkley Sophia K Tan Eric Tse Joanne Lee | 2023/5/26 |
Zfp106 binds to G-quadruplex RNAs and inhibits RAN translation and formation of RNA foci caused by G4C2 repeats | bioRxiv | Barbara Celona Haifan Wu Bobo Dang Huong T Kratochvil William F DeGrado | 2023/3/5 |
Inhibitors of alpha 2 beta 1 integrin and methods of use thereof | 2023/5/9 | ||
Hexamethylene amiloride binds the SARS‐CoV‐2 envelope protein at the protein–lipid interface | Protein Science | Noah H Somberg João Medeiros‐Silva Hyunil Jo Jun Wang William F DeGrado | 2023/10 |
Designed Transmembrane Proteins Inhibit the Erythropoietin Receptor in a Custom Binding Topology | bioRxiv | Marco Mravic Li He Huong Kratochvil Hailin Hu Sarah E Nick | 2023/2/15 |
Transient water wires mediate selective proton conduction in designed channel proteins | bioRxiv | Huong T Kratochvil Laura C Watkins Marco Mravic JL Thomaston Lijun Liu | 2022 |
De novo design of a β-lactamase in a modular helical bundle protein scaffold | Biophysical Journal | Samuel H Schneider William DeGrado | 2022/2/11 |
