Werner Geldenhuys

Werner Geldenhuys

West Virginia University

H-index: 46

North America-United States

About Werner Geldenhuys

Werner Geldenhuys, With an exceptional h-index of 46 and a recent h-index of 31 (since 2020), a distinguished researcher at West Virginia University, specializes in the field of drug discovery, mitochondrial dysfunction, mitoNEET, cisd2, iron-sulfur.

His recent articles reflect a diverse array of research interests and contributions to the field:

Mitoneet and Its Regulation of Mitochondrial Metabolism in Pulmonary Hypertension

Targeting myeloperoxidase limits myeloid cell immunosuppression enhancing immune checkpoint therapy for pancreatic cancer

Preclinical Multi-Omic Assessment of Pioglitazone in Skeletal Muscles of Mice Implanted with Human HER2/neu Overexpressing Breast Cancer Xenografts

Flash nanoprecipitation assisted self-assembly of ionizable lipid nanoparticles for nucleic acid delivery

Flash nanoprecipitation allows easy fabrication of pH-responsive acetalated dextran nanoparticles for intracellular release of payloads

Chloroquine reduces neutrophil extracellular trap (NET) formation through inhibition of peptidyl arginine deiminase 4 (PAD4)

Cancer-associated somatic mutations in human phosphofructokinase-1 reveal a critical electrostatic interaction for allosteric regulation of enzyme activity

Chemotherapeutic activity of pitavastatin in vincristine resistant B-cell acute lymphoblastic leukemia

Werner Geldenhuys Information

University

Position

___

Citations(all)

6412

Citations(since 2020)

2878

Cited By

4620

hIndex(all)

46

hIndex(since 2020)

31

i10Index(all)

122

i10Index(since 2020)

87

Email

University Profile Page

West Virginia University

Google Scholar

View Google Scholar Profile

Werner Geldenhuys Skills & Research Interests

drug discovery

mitochondrial dysfunction

mitoNEET

cisd2

iron-sulfur

Top articles of Werner Geldenhuys

Title

Journal

Author(s)

Publication Date

Mitoneet and Its Regulation of Mitochondrial Metabolism in Pulmonary Hypertension

MR Smith

AW Trammell

H Karmouty-Quintana

W Geldenhuys

MC Hart

2024/5

Targeting myeloperoxidase limits myeloid cell immunosuppression enhancing immune checkpoint therapy for pancreatic cancer

Cancer Immunology, Immunotherapy

Angisha Basnet

Kaitlyn M Landreth

Remi Nohoesu

Stell P Santiago

Werner J Geldenhuys

...

2024/3

Preclinical Multi-Omic Assessment of Pioglitazone in Skeletal Muscles of Mice Implanted with Human HER2/neu Overexpressing Breast Cancer Xenografts

bioRxiv

Stuart A Clayton

Alan D Mizener

Marcella Whetsell

Lauren E Rentz

Ethan M Meadows

...

2024

Flash nanoprecipitation assisted self-assembly of ionizable lipid nanoparticles for nucleic acid delivery

Nanoscale

Bishal Misra

Krystal A Hughes

William H Pentz

Parinya Samart

Werner J Geldenhuys

...

2024

Flash nanoprecipitation allows easy fabrication of pH-responsive acetalated dextran nanoparticles for intracellular release of payloads

Discover Nano

Krystal A Hughes

Bishal Misra

Maryam Maghareh

Parinya Samart

Ethan Nguyen

...

2024/12

Chloroquine reduces neutrophil extracellular trap (NET) formation through inhibition of peptidyl arginine deiminase 4 (PAD4)

Clinical and Experimental Immunology

Abby D Ivey

B Matthew Fagan

Pranav Murthy

Michael T Lotze

Herbert J Zeh III

...

2023/3/1

Cancer-associated somatic mutations in human phosphofructokinase-1 reveal a critical electrostatic interaction for allosteric regulation of enzyme activity

Biochemical Journal

Maria A Voronkova

Heather L Hansen

Madison P Cooper

Jacob Miller

Narayanasami Sukumar

...

2023/9/1

Chemotherapeutic activity of pitavastatin in vincristine resistant B-cell acute lymphoblastic leukemia

Cancers

Debbie Piktel

Javohn C Moore

Sloan Nesbit

Samuel A Sprowls

Michael D Craig

...

2023/1/24

Evaluating the Perception of Artificial Intelligence Among the PharmD Students in West Virginia University

American Journal of Pharmaceutical Education

Mohammad Al-Mamun

Marina Galvez

Werner Geldenhuys

Ronald Reed

David Elliott

2023/8/1

Role of cytochrome P450-epoxygenase and soluble epoxide hydrolase in the regulation of vascular response

Mohammed A Nayeem

Werner J Geldenhuys

Ahmad Hanif

2023/1/1

Development of a fluorescence screening assay for binding partners of the iron-sulfur mitochondrial protein mitoNEET

Bioorganic & Medicinal Chemistry Letters

Ebenezer Newton

Sarah A Starcovic

Michael Menze

Mary E Konkle

Timothy E Long

...

2023/6/1

Release of hepatic xanthine oxidase (XO) to the circulation is protective in intravascular hemolytic crisis

Redox Biology

Heidi M Schmidt

Evan R DeVallance

Sara E Lewis

Katherine C Wood

Gowtham K Annarapu

...

2023/6/1

Biochemical control of the mitochondrial protein MitoNEET by biological thiols and lipid-derived electrophiles

Advances in Redox Research

Robert A Skolik

Collin Noud

Sydney Oliver

J Markitan

L Salazar

...

2023/4/1

SOX71, A Biocompatible Succinyl Derivative of the Triarylmethyl Radical OX071 for In Vivo Quantitative Oxygen Mapping Using Electron Paramagnetic Resonance

Molecular Imaging and Biology

Misa A Shaw

Martin Poncelet

Navin Viswakarma

Gian Paolo Vallerini

Safa Hameed

...

2023/11/9

Identification of Natural Product Sulfuretin Derivatives as Inhibitors for the Endoplasmic Reticulum Redox Protein ERO1α

ACS bio & med chem Au

Brennan D Johnson

Sridhar Reddy Kaulagari

Wei-Chih Chen

Karen Hayes

Werner J Geldenhuys

...

2022/1/20

Rescue of a peroxisome proliferator activated receptor gamma gene network in muscle after growth of human breast tumour xenografts

JCSM Rapid Communications

David A Stanton

Hannah E Wilson

Matthew G Chapa

Jessica N Link

Kristin Lupinacci

...

2022/7

Adipose tissue macrophages exert systemic metabolic control by manipulating local iron concentrations

Nature Metabolism

Nolwenn Joffin

Christy M Gliniak

Jan-Bernd Funcke

Vivian A Paschoal

Clair Crewe

...

2022/11

ERO1α as a potential target in EGFR driven non-small cell lung cancer

Cancer Research

Brennan D Johnson

Wei-Chih Chen

Werner J Geldenhuys

Lori A Hazlehurst

2022/6/15

Unraveling Novel Roles of Xanthine Oxidase in Sickle Cell Disease

Heidi Marie Schmidt

2022

MitoNEET’s reactivity of Lys55 toward pyridoxal phosphate demonstrates its activity as a transaminase enzyme

ACS Chemical Biology

Courtney Kunk

Josh Kruger

George Mendoza

Joey Markitan

Taylor Bias

...

2022/10/4

See List of Professors in Werner Geldenhuys University(West Virginia University)