Wen-Hsiang Chen, Ph.D.

Wen-Hsiang Chen, Ph.D.

University of Houston

H-index: 20

North America-United States

About Wen-Hsiang Chen, Ph.D.

Wen-Hsiang Chen, Ph.D., With an exceptional h-index of 20 and a recent h-index of 16 (since 2020), a distinguished researcher at University of Houston, specializes in the field of Biochemistry, Chemical Engineering.

His recent articles reflect a diverse array of research interests and contributions to the field:

Choice of adjuvant and antigen composition alters the immunogenic profile of a SARS-CoV-2 subunit vaccine

Biophysical and biochemical characterization of a recombinant Lyme disease vaccine antigen, CspZ-YA

From concept to delivery: a yeast-expressed recombinant protein-based COVID-19 vaccine technology suitable for global access

A Recombinant Protein XBB. 1.5 RBD/Alum/CpG Vaccine Elicits High Neutralizing Antibody Titers against Omicron Subvariants of SARS-CoV-2

CspZ FH-binding sites as epitopes promote antibody-mediated Lyme borreliae clearance

Receptor-binding domain recombinant protein on alum-CpG induces broad protection against SARS-CoV-2 variants of concern

Yeast-expressed recombinant SARS-CoV-2 receptor binding domain RBD203-N1 as a COVID-19 protein vaccine candidate

A novel multi-epitope recombinant protein elicits an antigen-specific CD8+ T cells response in Trypanosoma cruzi-infected mice

Wen-Hsiang Chen, Ph.D. Information

University

Position

/Baylor College of Medicine/ Texas Children's Hospital

Citations(all)

1902

Citations(since 2020)

1725

Cited By

859

hIndex(all)

20

hIndex(since 2020)

16

i10Index(all)

21

i10Index(since 2020)

18

Email

University Profile Page

University of Houston

Google Scholar

View Google Scholar Profile

Wen-Hsiang Chen, Ph.D. Skills & Research Interests

Biochemistry

Chemical Engineering

Top articles of Wen-Hsiang Chen, Ph.D.

Title

Journal

Author(s)

Publication Date

Choice of adjuvant and antigen composition alters the immunogenic profile of a SARS-CoV-2 subunit vaccine

Frontiers in Drug Delivery

William R Lykins

Jeroen Pollet

Jessica A White

Brian Keegan

Leroy Versteeg

...

2024/2/7

Biophysical and biochemical characterization of a recombinant Lyme disease vaccine antigen, CspZ-YA

International Journal of Biological Macromolecules

Yi-Lin Chen

Jungsoon Lee

Zhuyun Liu

Ulrich Strych

Maria Elena Bottazzi

...

2024/2/1

From concept to delivery: a yeast-expressed recombinant protein-based COVID-19 vaccine technology suitable for global access

Peter J Hotez

Rakesh Adhikari

Wen-Hsiang Chen

Yi-Lin Chen

Portia Gillespie

...

2023/12/31

A Recombinant Protein XBB. 1.5 RBD/Alum/CpG Vaccine Elicits High Neutralizing Antibody Titers against Omicron Subvariants of SARS-CoV-2

Vaccines

Syamala Rani Thimmiraju

Rakesh Adhikari

Maria Jose Villar

Jungsoon Lee

Zhuyun Liu

...

2023/10/1

CspZ FH-binding sites as epitopes promote antibody-mediated Lyme borreliae clearance

Infection and Immunity

Yi-Lin Chen

Ashley L Marcinkiewicz

Tristan A Nowak

Rakhi Tyagi Kundu

Zhuyun Liu

...

2022/7/21

Receptor-binding domain recombinant protein on alum-CpG induces broad protection against SARS-CoV-2 variants of concern

Vaccine

Jeroen Pollet

Ulrich Strych

Wen-Hsiang Chen

Leroy Versteeg

Brian Keegan

...

2022/6/9

Yeast-expressed recombinant SARS-CoV-2 receptor binding domain RBD203-N1 as a COVID-19 protein vaccine candidate

Protein Expression and Purification

Wen-Hsiang Chen

Jeroen Pollet

Ulrich Strych

Jungsoon Lee

Zhuyun Liu

...

2022/2/1

A novel multi-epitope recombinant protein elicits an antigen-specific CD8+ T cells response in Trypanosoma cruzi-infected mice

Vaccine

Cristina González-López

Wen-Hsiang Chen

Andrea Alfaro-Chacón

Liliana E Villanueva-Lizama

Miguel Rosado-Vallado

...

2022/10/26

Past, present, and future of Lyme disease vaccines: antigen engineering approaches and mechanistic insights

Wen-Hsiang Chen

Ulrich Strych

Maria Elena Bottazzi

Yi-Pin Lin

2022/10/3

Genetic modification to design a stable yeast-expressed recombinant SARS-CoV-2 receptor binding domain as a COVID-19 vaccine candidate

Biochimica et Biophysica Acta (BBA)-General Subjects

Wen-Hsiang Chen

Junfei Wei

Rakhi Tyagi Kundu

Rakesh Adhikari

Zhuyun Liu

...

2021/6/1

Process development and scale-up optimization of the SARS-CoV-2 receptor binding domain–based vaccine candidate, RBD219-N1C1

Applied microbiology and biotechnology

Jungsoon Lee

Zhuyun Liu

Wen-Hsiang Chen

Junfei Wei

Rakhi Kundu

...

2021/5

Recombinant protein vaccines, a proven approach against coronavirus pandemics

Jeroen Pollet

Wen-Hsiang Chen

Ulrich Strych

2021/3/1

A scalable and reproducible manufacturing process for Phlebotomus papatasi salivary protein PpSP15, a vaccine candidate for leishmaniasis

Protein Expression and Purification

Zhuyun Liu

Rakhi Kundu

Surafel Damena

Amadeo B Biter

Mun Peak Nyon

...

2021/1/1

SARS‑CoV-2 RBD219-N1C1: A yeast-expressed SARS-CoV-2 recombinant receptor-binding domain candidate vaccine stimulates virus neutralizing antibodies and T-cell immunity in mice

Human vaccines & immunotherapeutics

Jeroen Pollet

Wen-Hsiang Chen

Leroy Versteeg

Brian Keegan

Bin Zhan

...

2021/8/3

A yeast-expressed RBD-based SARS-CoV-2 vaccine formulated with 3M-052-alum adjuvant promotes protective efficacy in non-human primates

Science immunology

Maria Pino

Talha Abid

Susan Pereira Ribeiro

Venkata Viswanadh Edara

Katharine Floyd

...

2021/7/15

Potential for developing a SARS-CoV receptor-binding domain (RBD) recombinant protein as a heterologous human vaccine against coronavirus infectious disease (COVID)-19

Wen-Hsiang Chen

Peter J Hotez

Maria Elena Bottazzi

2020/6/2

The SARS-CoV-2 vaccine pipeline: an overview

Wen-Hsiang Chen

Ulrich Strych

Peter J Hotez

Maria Elena Bottazzi

2020/6

Process characterization and biophysical analysis for a yeast-expressed Phlebotomus papatasi salivary protein (PpSP15) as a Leishmania vaccine candidate

Journal of pharmaceutical sciences

Wen-Hsiang Chen

Mun Peak Nyon

Mohan V Poongavanam

Zhuyun Liu

Amadeo B Biter

...

2020/5/1

The factor H-binding site of CspZ as a protective target against multistrain, tick-transmitted Lyme disease

Infection and immunity

Ashley L Marcinkiewicz

Ilva Lieknina

Xiuli Yang

Patricia L Lederman

Thomas M Hart

...

2020/4/20

Yeast-expressed SARS-CoV recombinant receptor-binding domain (RBD219-N1) formulated with alum induces protective immunity and reduces immune enhancement

Vaccine

Wen-Hsiang Chen

Xinrong Tao

Anurodh Shankar Agrawal

Abdullah Algaissi

Bi-Hung Peng

...

2020/11/3

See List of Professors in Wen-Hsiang Chen, Ph.D. University(University of Houston)