Toril Holien

About Toril Holien

Toril Holien, With an exceptional h-index of 28 and a recent h-index of 20 (since 2020), a distinguished researcher at Norges teknisk-naturvitenskaplige universitet, specializes in the field of Cell signaling, multiple myeloma, cell biology, immunology, cancer.

His recent articles reflect a diverse array of research interests and contributions to the field:

Genome-Wide CRISPR/Cas9 Knock-out Screen Identifies Apoptosis-Relevant Genes in Multiple Myeloma

P-364 Novel FKBP12 targeting PROTACs enhances BMP-induced apoptosis in multiple myeloma

Targeting FKBP12 enables bone morphogenetic proteins to kill multiple myeloma cells via ALK2

High concentrations of soluble endoglin can inhibit BMP9 signaling in non-endothelial cells

FKBP12 is a major regulator of ALK2 activity in multiple myeloma cells

Mutational analysis and protein profiling predict drug sensitivity in multiple myeloma cell lines

Mcl‐1 and Bcl‐xL levels predict responsiveness to dual MEK/Bcl‐2 inhibition in B‐cell malignancies

Article II. Mcl-1 and Bcl-xL levels predict responsiveness to dual MEK/Bcl-2 inhibition in B cell malignancies

Toril Holien Information

University

Position

Researcher at Norway

Citations(all)

1923

Citations(since 2020)

1176

Cited By

1252

hIndex(all)

28

hIndex(since 2020)

20

i10Index(all)

36

i10Index(since 2020)

33

Email

University Profile Page

Google Scholar

Toril Holien Skills & Research Interests

Cell signaling

multiple myeloma

cell biology

immunology

cancer

Top articles of Toril Holien

Title

Journal

Author(s)

Publication Date

Genome-Wide CRISPR/Cas9 Knock-out Screen Identifies Apoptosis-Relevant Genes in Multiple Myeloma

Blood

Clara Leticia Andersson-Rusch

Ingrid Quist-Løkken

Pål Sætrom

Vidar Beisvåg

Milosz Rolinski

...

2023/11/28

P-364 Novel FKBP12 targeting PROTACs enhances BMP-induced apoptosis in multiple myeloma

Clinical Lymphoma Myeloma and Leukemia

Ingrid Quist-Lokken

Michael Walz

Felix Hausch

Toril Holien

2023/9/1

Targeting FKBP12 enables bone morphogenetic proteins to kill multiple myeloma cells via ALK2

Ingrid Quist-Løkken

Clara Andersson-Rusch

Martin Haugrud Kastnes

Jürgen Markus Kolos

Jerome Jatzlau

...

2023/8/18

High concentrations of soluble endoglin can inhibit BMP9 signaling in non-endothelial cells

Scientific Reports

Clara Andersson-Rusch

Bin Liu

Ingrid Quist-Løkken

Paul D Upton

Oddrun Elise Olsen

...

2023/4/24

FKBP12 is a major regulator of ALK2 activity in multiple myeloma cells

Cell Communication and Signaling

Ingrid Quist-Løkken

Clara Andersson-Rusch

Martin Haugrud Kastnes

Jürgen Markus Kolos

Jerome Jatzlau

...

2023/1/30

Mutational analysis and protein profiling predict drug sensitivity in multiple myeloma cell lines

Frontiers in Oncology

Mariaserena Giliberto

Leonardo Miranda Santana

Toril Holien

Kristine Misund

Sigve Nakken

...

2022/11/29

Mcl‐1 and Bcl‐xL levels predict responsiveness to dual MEK/Bcl‐2 inhibition in B‐cell malignancies

Molecular Oncology

Katrine Melvold

Mariaserena Giliberto

Linda Karlsen

Pilar Ayuda‐Durán

Robert Hanes

...

2022/3

Article II. Mcl-1 and Bcl-xL levels predict responsiveness to dual MEK/Bcl-2 inhibition in B cell malignancies

Application of drug sensitivity screening in B-cell malignancies for informing precision medicine strategies

Katrine Melvold

Mariaserena Giliberto

Linda Karlsen

Pilar Ayuda-Durán

Richard Rosenquist

...

2022

Picomolar FKBP inhibitors enabled by a single water-displacing methyl group in bicyclic [4.3. 1] aza-amides

Chemical science

Jürgen M Kolos

Sebastian Pomplun

Sascha Jung

Benedikt Rieß

Patrick L Purder

...

2021

Application of photodynamic therapy with 5-aminolevulinic acid to extracorporeal photopheresis in the treatment of patients with chronic graft-versus-Host disease: A first-in …

Pharmaceutics

Eidi Christensen

Olav A Foss

Petter Quist-Paulsen

Ingrid Staur

Frode Pettersen

...

2021/9/26

Receptor binding competition: A paradigm for regulating TGF-β family action

Erik Martinez-Hackert

Anders Sundan

Toril Holien

2021/2/1

Bone morphogenetic protein 4 gene therapy in mice inhibits myeloma tumor growth, but has a negative impact on bone

Journal of Bone and Mineral Research Plus

Marita Westhrin

Toril Holien

Muhammad Zahoor

Siv Helen Moen

Glenn Buene

...

2020/1/1

Modification of extracorporeal photopherisis technology with porphyrin precursors

2020/6/30

Chemical, physical and biological triggers of evolutionary conserved Bcl-xL-mediated apoptosis

Cancers

Aleksandr Ianevski

Evgeny Kulesskiy

Klara Krpina

Guofeng Lou

Yahyah Aman

...

2020/6/25

Activins as dual specificity TGF-β family molecules: SMAD-activation via activin-and BMP-type 1 receptors

Biomolecules

Oddrun Elise Olsen

Hanne Hella

Samah Elsaadi

Carsten Jacobi

Erik Martinez-Hackert

...

2020/3/29

Selective killing of activated t cells by 5-aminolevulinic acid mediated photodynamic effect: Potential improvement of extracorporeal photopheresis

Cancers

Sagar Darvekar

Petras Juzenas

Morten Oksvold

Andrius Kleinauskas

Toril Holien

...

2020/2/6

See List of Professors in Toril Holien University(Norges teknisk-naturvitenskaplige universitet)

Co-Authors

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