Tom H.M. Ottenhoff, MD, PhD

Tom H.M. Ottenhoff, MD, PhD

Universiteit Leiden

H-index: 114

Europe-Netherlands

About Tom H.M. Ottenhoff, MD, PhD

Tom H.M. Ottenhoff, MD, PhD, With an exceptional h-index of 114 and a recent h-index of 53 (since 2020), a distinguished researcher at Universiteit Leiden, specializes in the field of Immunology, immunogenetics, cell-biology, biomarkers, vaccines..

His recent articles reflect a diverse array of research interests and contributions to the field:

Multi-ancestry meta-analysis of host genetic susceptibility to tuberculosis identifies shared genetic architecture

Identification of kinase modulators as host-directed therapeutics against intracellular methicillin-resistant Staphylococcus aureus

Mtb HLA-E-tetramer-sorted CD8+ T cells have a diverse TCR repertoire

Refined innate plasma signature after rVSVΔG-ZEBOV-GP immunization is shared among adult cohorts in Europe and North America

Longitudinal soluble marker profiles reveal strong association between cytokine storms resulting from macrophage activation and disease severity in COVID-19 disease

BCG vaccination-induced acquired control of mycobacterial growth differs from growth control preexisting to BCG vaccination

Intrinsic immunogenicity of liposomes for tuberculosis vaccines: effect of cationic lipid and cholesterol

Whole blood RNA signatures in tuberculosis patients receiving H56: IC31 vaccine as adjunctive therapy

Tom H.M. Ottenhoff, MD, PhD Information

University

Position

Professor in Immunology of Mycobacterial Infectious Diseases at LUMC

Citations(all)

44926

Citations(since 2020)

13158

Cited By

37148

hIndex(all)

114

hIndex(since 2020)

53

i10Index(all)

439

i10Index(since 2020)

296

Email

University Profile Page

Universiteit Leiden

Google Scholar

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Tom H.M. Ottenhoff, MD, PhD Skills & Research Interests

Immunology

immunogenetics

cell-biology

biomarkers

vaccines.

Top articles of Tom H.M. Ottenhoff, MD, PhD

Title

Journal

Author(s)

Publication Date

Multi-ancestry meta-analysis of host genetic susceptibility to tuberculosis identifies shared genetic architecture

Elife

Haiko Schurz

Vivek Naranbhai

Tom A Yates

James J Gilchrist

Tom Parks

...

2024/1/15

Identification of kinase modulators as host-directed therapeutics against intracellular methicillin-resistant Staphylococcus aureus

Frontiers in Cellular and Infection Microbiology

Robin HGA van den Biggelaar

Kimberley V Walburg

Susan JF van den Eeden

Cassandra LR van Doorn

Eugenia Meiler

...

2024/3/25

Mtb HLA-E-tetramer-sorted CD8+ T cells have a diverse TCR repertoire

Iscience

Linda Voogd

Anne MHF Drittij

Calinda KE Dingenouts

Kees LMC Franken

Vincent van Unen

...

2024/3/15

Refined innate plasma signature after rVSVΔG-ZEBOV-GP immunization is shared among adult cohorts in Europe and North America

Frontiers in Immunology

Paola Andrea Martinez-Murillo

Angela Huttner

Sylvain Lemeille

Donata Medaglini

Tom HM Ottenhoff

...

2024/1/3

Longitudinal soluble marker profiles reveal strong association between cytokine storms resulting from macrophage activation and disease severity in COVID-19 disease

Meijgaarden Kv

S Veen

R Tsonaka

P Ruibal

AH Roukens

...

2024/3/5

BCG vaccination-induced acquired control of mycobacterial growth differs from growth control preexisting to BCG vaccination

Nature Communications

Krista E van Meijgaarden

Wenchao Li

Simone JCFM Moorlag

Valerie ACM Koeken

Hans JPM Koenen

...

2024/1/2

Intrinsic immunogenicity of liposomes for tuberculosis vaccines: effect of cationic lipid and cholesterol

European Journal of Pharmaceutical Sciences

MM Szachniewicz

MA Neustrup

KE van Meijgaarden

W Jiskoot

JA Bouwstra

...

2024/2/20

Whole blood RNA signatures in tuberculosis patients receiving H56: IC31 vaccine as adjunctive therapy

Frontiers in Immunology

Noelia Alonso-Rodríguez

Eleonora Vianello

Suzanne van Veen

Synne Jenum

Kristian Tonby

...

2024/2/16

Age and sex influence antibody profiles associated with tuberculosis progression

Nature Microbiology

Leela RL Davies

Chuangqi Wang

Pia Steigler

Kathryn A Bowman

Stephanie Fischinger

...

2024/4/24

Random forest and live single‐cell metabolomics reveal metabolic profiles of human macrophages upon polarization

Biotechnology and Bioengineering

Huaqi Tang

Ahmed Ali

Eman Abdelazem

Tom HM Ottenhoff

Ron MA Heeren

...

2023/8

Antibody responses to recombinant vesicular stomatitis virus-Zaire Ebolavirus vaccination for Ebola virus disease across doses and continents: 5-year durability

Clinical Microbiology and Infection

Angela Huttner

Selidji Todagbe Agnandji

Olivier Engler

Jay W Hooper

Steve Kwilas

...

2023/12/1

Potential business model for a European vaccine R&D infrastructure and its estimated socio-economic impact

F1000Research

Stefan Jungbluth

William Martin

Monika Slezak

Hilde Depraetere

Carlos A Guzman

...

2023

BCG Revaccination of Young Indian Adults Enhances Pro-Inflammatory Markers of Trained Immunity with Concomitant Induction of Major Anti-Inflammatory Pathways

Asma Ahmed

Himanshu Tripathi

Krista E van Meijgaarden

Nirutha Chetan

Vasista Adiga

...

2023/3/24

Identification of circulating monocytes as producers of tuberculosis disease biomarker C1q

Scientific Reports

Paula Niewold

Douwe J Dijkstra

Yi Cai

Delia Goletti

Fabrizio Palmieri

...

2023/7/18

Defining discriminatory antibody fingerprints in active and latent tuberculosis (vol 13, 856906, 2022)

Frontiers in immunology

Nadege Nziza

Deniz Cizmeci

Leela Davies

Edward B Irvine

Wonyeong Jung

...

2022/4/20

Airway epithelial cells mount an early response to mycobacterial infection

Frontiers in Cellular and Infection Microbiology

Amy M Barclay

Dennis K Ninaber

Suzanne Van Veen

Pieter S Hiemstra

Tom HM Ottenhoff

...

2023

Thermal‐exchange HLA‐E multimers reveal specificity in HLA‐E and NKG2A/CD94 complex interactions

Immunology

Paula Ruibal

Ian Derksen

Marjolein van Wolfswinkel

Linda Voogd

Kees LMC Franken

...

2023/3

Extensive flow cytometric immunophenotyping of human PBMC incorporating detection of chemokine receptors, cytokines and tetramers

Cytometry Part A

Marjolein van Wolfswinkel

Krista E van Meijgaarden

Tom HM Ottenhoff

Paula Niewold

Simone A Joosten

2023/7

Baseline gene signatures of reactogenicity to Ebola vaccination: a machine learning approach across multiple cohorts

Frontiers in Immunology

Patrícia Conceição Gonzalez Dias Carvalho

Thiago Dominguez Crespo Hirata

Leandro Yukio Mano Alves

Isabelle Franco Moscardini

Ana Paula Barbosa do Nascimento

...

2023/11/8

Identification of kinase inhibitors as potential host-directed therapies for intracellular bacteria

bioRxiv

Robin HGA van den Biggelaar

Kimberley V Walburg

Susan van den Eeden

Cassandra LR van Doorn

Eugenia Meiler

...

2023

See List of Professors in Tom H.M. Ottenhoff, MD, PhD University(Universiteit Leiden)

Co-Authors

H-index: 142
Leo Joosten

Leo Joosten

Radboud Universiteit

H-index: 66
Francesco Dieli

Francesco Dieli

Università degli Studi di Palermo

H-index: 51
Bachti Alisjahbana

Bachti Alisjahbana

Universitas Padjadjaran

H-index: 43
Esther van de Vosse

Esther van de Vosse

Universiteit Leiden

H-index: 21
Edhyana Sahiratmadja

Edhyana Sahiratmadja

Universitas Padjadjaran

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