TJ Ley
Washington University in St. Louis
H-index: 109
North America-United States
Top articles of TJ Ley
Title | Journal | Author(s) | Publication Date |
---|---|---|---|
Proteogenomic analysis reveals cytoplasmic sequestration of RUNX1 by the acute myeloid leukemia–initiating CBFB:: MYH11 oncofusion protein | The Journal of Clinical Investigation | Ryan B Day Julia A Hickman Ziheng Xu Casey DS Katerndahl Francesca Ferraro | 2024/2/15 |
Stabilizing the Proteomes of Acute Myeloid Leukemia Cells: Implications for Cancer Proteomics | Molecular & Cellular Proteomics | Robert W Sprung Qiang Zhang Michael H Kramer Matthew C Christopher Petra Erdmann-Gilmore | 2024/2/1 |
Rapid and accurate remethylation of DNA in Dnmt3a-deficient hematopoietic cells with restoration of DNMT3A activity | Science Advances | Yang Li Haley J Abel Michelle Cai Taylor A LaValle Tiankai Yin | 2024/1/31 |
PML:: RARA and GATA2 proteins interact via DNA templates to induce aberrant self-renewal in mouse and human hematopoietic cells | Proceedings of the National Academy of Sciences | Casey DS Katerndahl Olivia RS Rogers Ryan B Day Ziheng Xu Nichole M Helton | 2024/4/30 |
CBFB::MYH11 expression activates Trp53 in myeloid cells, which inhibits cell growth and sensitizes cells to cytarabine | Cancer Research | Ryan B Day Julia A Hickman Casey D Katerndahl Sai Mukund Ramakrishnan Christopher A Miller | 2024/3/22 |
Persistent molecular disease in adult patients with AML evaluated with whole-exome and targeted error-corrected DNA sequencing | JCO Precision Oncology | Michael J Slade Reza Ghasemi Michelle O'Laughlin Tasha Burton Robert S Fulton | 2023/4 |
Rapid and Accurate Remethylation of Dnmt3a Deficient Hematopoietic Cells with Restoration of DNMT3A Activity | Blood | Yang Li Haley Abel Michelle Cai Taylor Lavalle Tiankai Yin | 2023/11/28 |
Description of a novel subtype of acute myeloid leukemia defined by recurrent CBFB insertions | Blood | Georgina L Ryland Masayuki Umeda Linda Holmfeldt Sören Lehmann Morten Krogh Herlin | 2023/2/16 |
Overexpression of the Signaling Integrator Gab2 Accelerates AML Development in Mice with Dnmt3a R878Hand Npm1 cA Mutations | Blood | Michael H Kramer Stephanie Richardson Yang Li Nichole Helton Daniel George | 2023/11/28 |
Genomic landscape of TP53-mutated myeloid malignancies | Blood Advances | Haley J Abel Karolyn A Oetjen Christopher A Miller Sai M Ramakrishnan Ryan B Day | 2023/8/22 |
Methods and compositions for treatment of cancer | 2023/7/11 | ||
Mechanisms of PML:: Rara and GATA2 Protein Interactions in Hematopoietic Cells | Blood | Casey Katerndahl Olivia Rogers Nichole Helton Sai Mukund Ramakrishnan Christopher A Miller | 2023/11/28 |
Melanoma in a patient with DNMT3A overgrowth syndrome | Molecular Case Studies | David Y Chen Leslie A Sutton Sai Mukund Ramakrishnan Eric J Duncavage Sharon E Heath | 2023/4/1 |
Assessment of T-Cell Receptor (TCR) Mediated T-Cell Activation in Acute Myeloid Leukemia at Diagnosis Has Implications for Risk Stratification and Response to Immune Checkpoint … | Blood | Nancy BJ Arthur Agata Gruszczynska Ma Xenia G Illagan Michael Prinsen Sharon E Heath | 2023/11/28 |
Somatic Dnmt3a inactivation leads to slow, canonical DNA methylation loss in murine hematopoietic cells | Iscience | Amanda M Smith Angela M Verdoni Haley J Abel David Y Chen Shamika Ketkar | 2022/4/15 |
A general approach for detecting expressed mutations in AML cells using single cell RNA-sequencing (vol 10, 3660, 2019) | Nature communications | Allegra A Petti Stephen R Williams Christopher A Miller Ian T Fiddes Sridhar N Srivatsan | 2019/8/14 |
The Protein Interactomes of CBFB-MYH11 and RUNX1-RUNX1T1 Suggest Different Mechanisms of Action for Initiating Acute Myeloid Leukemia | Blood | Ryan B Day Julia Hickman Ziheng Xu Casey DS Katerndahl Francesca Ferraro | 2022/11/15 |
Tumor suppressor function of WT1 in acute promyelocytic leukemia | haematologica | Matthew J Christopher Casey DS Katerndahl Hayley R LeBlanc Tyler T Elmendorf Vaishali Basu | 2022/1/1 |
Focal disruption of DNA methylation dynamics at enhancers in IDH-mutant AML cells | Leukemia | Elisabeth R Wilson Nichole M Helton Sharon E Heath Robert S Fulton Jacqueline E Payton | 2022/4 |
Decitabine salvage for TP53-mutated, relapsed/refractory acute myeloid leukemia after cytotoxic induction therapy | Haematologica | Francesca Ferraro Agata Gruszczynska Marianna B Ruzinova Christopher A Miller Mary Elizabeth Percival | 2022/7/7 |