Timothy Springer
Harvard University
H-index: 192
North America-United States
Top articles of Timothy Springer
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
Synthetic integrin antibodies discovered by yeast display reveal αV subunit pairing preferences with β subunits | bioRxiv | Yuxin Hao Jiabin Yan Courtney Fraser Aiping Jiang Murali Anuganti | 2024 |
Modified integrin polypeptides, modified integrin polypeptide dimers, and uses thereof | 2022/3/3 | ||
A specialized integrin-binding motif enables proTGF-β2 activation by integrin αVβ6 but not αVβ8 | Proceedings of the National Academy of Sciences | Viet Q Le Bo Zhao Siddanth Ramesh Cameron Toohey Adam DeCosta | 2023/6/13 |
De novo design of highly selective miniprotein inhibitors of integrins αvβ6 and αvβ8 | Nature Communications | Anindya Roy Lei Shi Ashley Chang Xianchi Dong Andres Fernandez | 2023/9/13 |
Structural insights into MIC2 recognition by MIC2-associated protein in Toxoplasma gondii | Communications Biology | Su Zhang Fangfang Wang Dujuan Zhang Dongsheng Liu Wei Ding | 2023/8/31 |
Conformational change of Plasmodium TRAP is essential for sporozoite migration and transmission | EMBO reports | Friedrich Braumann Dennis Klug Jessica Kehrer Gaojie Song Juan Feng | 2023/6/12 |
A recombinant technique for mapping functional sites of heterotrimeric collagen helices: Collagen IV CB3 fragment as a prototype for integrin binding | Journal of Biological Chemistry | Sergei P Boudko Elizabeth H Konopka Woojin Kim Yuki Taga Kazunori Mizuno | 2023/7/1 |
Structures of VWF tubules before and after concatemerization reveal a mechanism of disulfide bond exchange | Blood, The Journal of the American Society of Hematology | Jacob R Anderson Jing Li Timothy A Springer Alan Brown | 2022/9/22 |
Shear flow has minimal role in unfolding of free von Willebrand factor | Biophysical Journal | Hans Bergal Yan Jiang Darren Yang Timothy A Springer Wesley P Wong | 2022/2/11 |
Regulation of integrin α5β1 conformational states and intrinsic affinities by metal ions and the ADMIDAS | Molecular Biology of the Cell | Jordan M Anderson Jing Li Timothy A Springer | 2022/5/15 |
A general chemical principle for creating closure-stabilizing integrin inhibitors | Cell | Fu-Yang Lin Jing Li Yonghua Xie Jianghai Zhu Thi Thu Huong Nguyen | 2022/9/15 |
Conformation of von Willebrand factor in shear flow revealed with stroboscopic single-molecule imaging | Blood, The Journal of the American Society of Hematology | Hans T Bergal Yan Jiang Darren Yang Timothy A Springer Wesley P Wong | 2022/12/8 |
Subtype-specific single-molecule mechanics for integrin activation, mechanotransduction and cytoskeleton remodeling | Biophysical Journal | Myung Hyun Jo Jing Li Valentin Jaumouillé Yuxin Hao Jessica Coppola | 2022/2/11 |
Von Willebrand factor A1 domain stability and affinity for GPIbα are differentially regulated by its O-glycosylated N-and C-linker | eLife | Klaus Bonazza Roxana E Iacob Nathan E Hudson Jing Li Chafen Lu | 2022/5/9 |
Dynamics of integrin α5β1, fibronectin, and their complex reveal sites of interaction and conformational change | Journal of Biological Chemistry | Yang Su Roxana E Iacob Jing Li John R Engen Timothy A Springer | 2022/9/1 |
Single-molecule characterization of subtype-specific β1 integrin mechanics | Nature communications | Myung Hyun Jo Jing Li Valentin Jaumouillé Yuxin Hao Jessica Coppola | 2022/12/3 |
Von Willebrand factor A1 domain affinity for GPIbα and stability are differentially regulated by its O-glycosylated N-linker and C-linker | bioRxiv | Klaus Bonazza Roxana E Iacob Nathan E Hudson Jing Li Chafen Lu | 2022/1/13 |
Regulation by metal ions and the ADMIDAS of integrin α5β1 conformational states and intrinsic affinities | Molecular Biology of the Cell | Jordan M Anderson Jing Li Timothy A Springer | 2022/4/15 |
Conformational change of the Plasmodium TRAP I domain is essential for sporozoite migration and transmission of malaria | bioRxiv | Friedrich Braumann Dennis Klug Jessica Kehrer Chafen Lu Timothy A Springer | 2022/8/25 |
Computational design of alpha (v) beta (6) integrin binding proteins | 2022/11/3 |
