Thomas Look
Harvard University
H-index: 138
North America-United States
Top articles of Thomas Look
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
Hyperactive STAT5 hijacks T cell receptor signaling and drives immature T cell acute lymphoblastic leukemia | Journal of Clinical Investigation | Tobias Suske Helena Sorger Gabriele Manhart Frank Ruge Nicole Prutsch | 2024/4/15 |
Novel combination therapy with a KAT6A/B inhibitor together with retinoids induces irreversible differentiation of neuroblastoma cells | Cancer Research | Nina Weichert-Leahey Alla Berezovskaya Mark Zimmerman Brian J Abraham Adam W Durbin | 2024/3/22 |
STAT3 couples activated tyrosine kinase signaling to the oncogenic core transcriptional regulatory circuitry of anaplastic large cell lymphoma | Suzanne Turner | 2024/2/23 | |
Depletion of tet2 results in age-dependent changes in DNA methylation and gene expression in a zebrafish model of myelodysplastic syndrome | Frontiers in hematology | Yaseswini Neelamraju Evisa Gjini Sagar Chhangawala Hao Fan Shuning He | 2023 |
Mechanisms and Therapeutic Strategies to Reverse TET2 Mutant Clonal Hematopoiesis and the Risk of MDS, AML, and Atherosclerotic Cardiovascular Disease | Blood | Nicole Prutsch Amélie Vromman Brittaney Leeper Mengyu Chen Shuning He | 2023/11/28 |
Genetic predisposition to neuroblastoma results from a regulatory polymorphism that promotes the adrenergic cell state | The Journal of clinical investigation | Nina Weichert-Leahey Hui Shi Ting Tao Derek A Oldridge Adam D Durbin | 2023/5/15 |
Synthetic lethal targeting of TET2‐mutant haematopoietic stem and progenitor cells by XPO1 inhibitors | British Journal of Haematology | Chang‐Bin Jing Nicole Prutsch Shuning He Mark W Zimmerman Yosef Landesman | 2023/5 |
ASCL1 dimerizes with TCF12 protein and activates BMP-SMAD1 pathway during subtype switching from mesenchymal towards adrenergic neuroblastoma | Cancer Research | Lu Wang Tze King Tan Hyoju Kim Dennis Kappei Shi Hao Tan | 2023/4/4 |
Targeting MET and FGFR in relapsed or refractory acute myeloid leukemia: preclinical and clinical findings, and signal transduction correlates | Clinical Cancer Research | Evan C Chen Helen Gandler Isidora Tošić Geoffrey G Fell Ashlee Fiore | 2023/3/1 |
ASCL1 characterizes adrenergic neuroblastoma via its pioneer function and cooperation with core regulatory circuit factors | Cell Reports | Lu Wang Tze King Tan Hyoju Kim Dennis Kappei Shi Hao Tan | 2023/12/26 |
Retraction notice to: Allosteric activators of protein phosphatase 2A display broad antitumor activity mediated by dephosphorylation of MYBL2 | Cell | Ken Morita Shuning He Radosław P Nowak Jinhua Wang Mark W Zimmerman | 2022/8/4 |
STAT5 gain-of-function variants promote precursor T-cell receptor activation to drive T-cell acute lymphoblastic leukemia | bioRxiv | Tobias Suske Helena Sorger Frank Ruge Nicole Prutsch Mark W Zimmerman | 2022/12/21 |
Compositions and methods of treating cancers by administering a phenothiazine-related drug that activates protein phosphatase 2a (pp2a) with reduced inhibitory activity … | 2022/3/3 | ||
Abstract PR005: Targeting EP300 and CBP for therapeutic benefit in pediatric solid tumors | Cancer Research | Adam D Durbin Noha Shendy Audrey Mercier Yang Zhang Melissa J Bikowitz | 2022/12/1 |
EP300 Selectively Controls the Enhancer Landscape of MYCN-Amplified Neuroblastoma | Cancer discovery | Adam D Durbin Tingjian Wang Virangika K Wimalasena Mark W Zimmerman Deyao Li | 2022/3/1 |
The Hematopoietic Transcription Factor GATA3 Is the Main Activator of Enhancer-Mediated Activation of Oncogenic TAL1 in T-ALL | Blood | Joana R Costa David O'Connor Nurkaiyisah Anuar Sunniyat Rahman Nivedita Singh | 2022/11/15 |
Association of allele-specific methylation of the ASNS gene with asparaginase sensitivity and prognosis in T-ALL | Blood Advances | Koshi Akahane Shunsuke Kimura Kunio Miyake Atsushi Watanabe Keiko Kagami | 2022/1/11 |
p53 Pathway Inactivation Drives SMARCB1-deficient p53-wildtype Epithelioid Sarcoma Onset Indicating Therapeutic Vulnerability Through MDM2 Inhibition | Molecular Cancer Therapeutics | Felix Oppel Senyao Shao Sarah Gendreizig Mark W Zimmerman Matthias Schürmann | 2022/11/3 |
STAT3 cooperates with the core transcriptional regulatory circuitry to drive MYC expression and oncogenesis in anaplastic large cell lymphoma | BioRxiv | Nicole Prutsch Shuning He Alla Berezovskaya Adam D Durbin Neekesh V Dharia | 2022/9/3 |
GAS7 deficiency promotes metastasis in MYCN-driven neuroblastoma | Cancer research | Zhiwei Dong Kok Siong Yeo Gonzalo Lopez Cheng Zhang Erin N Dankert Eggum | 2021/6/1 |
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