Thomas Durcan
McGill University
H-index: 26
North America-Canada
Top articles of Thomas Durcan
Loss of symmetric cell division of apical neural progenitors drives DENND5A-related developmental and epileptic encephalopathy
medRxiv
2022/8/26
Fares Kharfallah
H-Index: 2
Gopinath Kulasekaran
H-Index: 7
Armin Bayati
H-Index: 4
Stephanie Efthymiou
H-Index: 14
Kevin Huang
H-Index: 16
David Murphy
H-Index: 10
Matthew Osmond
H-Index: 8
Davut Pehlivan
H-Index: 24
Carol Saunders
H-Index: 28
Ziv Gan-Or
H-Index: 34
Massimo Avoli
H-Index: 37
Cesar Alves
H-Index: 5
Reza Maroofian
H-Index: 16
Secondary deficiency of neuraminidase 1 contributes to CNS pathology in neurological mucopolysaccharidoses via hypersialylation of brain glycoproteins
bioRxiv
2024
Christopher W Cairo
H-Index: 24
Thomas Durcan
H-Index: 14
Bénédicte Amilhon
H-Index: 11
Alexei Gorelik
H-Index: 10
14-3-3ζ regulates adipogenesis by modulating chromatin accessibility during the early stages of adipocyte differentiation
bioRxiv
2024
Transcriptome-based screening in TARDBP/TDP-43 knock-in motor neurons identifies the NEDD8-activating enzyme inhibitor MLN4924
bioRxiv
2024
Thomas Durcan
H-Index: 14
The 37TrillionCells initiative for improving global healthcare via cell-based interception and precision medicine: focus on neurodegenerative diseases
2024/12
Cover Image, Volume 72, Issue 6
Glia
2024/6
An adapted protocol to derive microglia from stem cells and its application in the study of CSF1R-related disorders
Molecular Neurodegeneration
2024/4/5
3D optoacoustic mesoscopy of neuromelanin in entire human midbrain organoids
2024/3/13
Illumination of understudied ciliary kinases
2024/3/8
Tom20 gates PINK1 activity and mediates its tethering of the TOM and TIM23 translocases upon mitochondrial stress
Proceedings of the National Academy of Sciences
2024/3/5
Generation of human iPSC-derived phrenic-like motor neurons to model respiratory motor neuron degeneration in ALS
Communications Biology
2024/2/28
Homozygous ALS-linked mutations in TARDBP/TDP-43 lead to hypoactivity and synaptic abnormalities in human iPSC-derived motor neurons
iScience
2024/2/9
A small molecule drug, AVP6, rescues synaptic deficits in human iPSC-derived neurons across the mucopolysaccharidosis type III spectrum
Molecular Genetics and Metabolism
2024/2/1
Thomas Durcan
H-Index: 14
MerTK is a mediator of alpha-synuclein fibril uptake by human microglia
Brain
2024/2
Early nuclear phenotypes and reactive transformation in human iPSC-derived astrocytes from ALS patients with SOD1 mutations
bioRxiv
2023
Guy Rouleau
H-Index: 89
Thomas Durcan
H-Index: 14
A genome-wide CRISPR/Cas9 screen identifies genes that regulate the cellular uptake of α-synuclein fibrils by modulating heparan sulfate proteoglycans
bioRxiv
2023
Neuroanatomical and cognitive biomarkers of alpha‐synuclein propagation in a mouse model of synucleinopathy prior to onset of motor symptoms
Journal of Neurochemistry
2023/10/7
Elucidating the impact of CSF1R variants on microglia development and function using patient-derived IPSCS
Journal of the Neurological Sciences
2023/12/1
Thomas Durcan
H-Index: 14
An adapted stem cell-derived microglia protocol for the study of microgliopathies and other neurological disorders
bioRxiv
2023
The neuro genomics partnership: A new consortium dedicated to a fully open patient to patient (P2P) integrative R&D approach
Journal of the Neurological Sciences
2023/12/1