Thomas C T Michaels

Thomas C T Michaels

University of Cambridge

H-index: 34

Europe-United Kingdom

About Thomas C T Michaels

Thomas C T Michaels, With an exceptional h-index of 34 and a recent h-index of 31 (since 2020), a distinguished researcher at University of Cambridge, specializes in the field of Biophysics, Soft matter, Statistical physics, Protein aggregation, Physics of Life.

His recent articles reflect a diverse array of research interests and contributions to the field:

Buffering of biomolecular condensate volume and mass in multi-component mixtures.

Self-replication of Aβ42 aggregates occurs on small and isolated fibril sites

The Alzheimer’s Aβ peptide forms biomolecular condensates that trigger amyloid aggregation

A solid beta-sheet structure is formed at the surface of FUS droplets during aging

Molecular mechanism of α-synuclein aggregation on lipid membranes revealed

Chemical Reactions regulated by Phase-Separated Condensates

Synchronization of chemical reactions in a population of phase-separated droplets

Understanding and controlling the molecular mechanisms of protein aggregation in mAb therapeutics

Thomas C T Michaels Information

University

Position

and Harvard University

Citations(all)

5199

Citations(since 2020)

4288

Cited By

2617

hIndex(all)

34

hIndex(since 2020)

31

i10Index(all)

69

i10Index(since 2020)

66

Email

University Profile Page

University of Cambridge

Google Scholar

View Google Scholar Profile

Thomas C T Michaels Skills & Research Interests

Biophysics

Soft matter

Statistical physics

Protein aggregation

Physics of Life

Top articles of Thomas C T Michaels

Title

Journal

Author(s)

Publication Date

Buffering of biomolecular condensate volume and mass in multi-component mixtures.

Bulletin of the American Physical Society

Logan de Monchaux-Irons

Thomas Michaels

Nina Han

Benjamin Frühbauer

Leonidas Emmanouilidis

...

2024/3/8

Self-replication of Aβ42 aggregates occurs on small and isolated fibril sites

Proceedings of the National Academy of Sciences

Samo Curk

Johannes Krausser

Georg Meisl

Daan Frenkel

Sara Linse

...

2024/2/13

The Alzheimer’s Aβ peptide forms biomolecular condensates that trigger amyloid aggregation

bioRxiv

Greta Šneiderienė

Alicia González Díaz

Sourav Das Adhikari

Jiapeng Wei

Thomas Michaels

...

2024/1/15

A solid beta-sheet structure is formed at the surface of FUS droplets during aging

bioRxiv

Leonidas Emmanouilidis

Ettore Bartalucci

Yelena Kan

Mahdiye Ijavi

Maria Escura Pérez

...

2023

Molecular mechanism of α-synuclein aggregation on lipid membranes revealed

Chemical Science

Alexander J Dear

Xiangyu Teng

Sarah R Ball

Joshua Lewin

Robert I Horne

...

2024

Chemical Reactions regulated by Phase-Separated Condensates

arXiv preprint arXiv:2403.05228

Sudarshana Laha

Jonathan Bauermann

Frank Jülicher

Thomas CT Michaels

Christoph A Weber

2024/3/8

Synchronization of chemical reactions in a population of phase-separated droplets

Bulletin of the American Physical Society

Alisdair Stevenson

Sudarshana Laha

Christoph Weber

Thomas Michaels

2024/3/8

Understanding and controlling the molecular mechanisms of protein aggregation in mAb therapeutics

Kuin Tian Pang

Yuan Sheng Yang

Wei Zhang

Ying Swan Ho

Pietro Sormanni

...

2023/6/7

The interplay between molecular assembly and phase separation

bioRxiv

Giacomo Bartolucci

Thomas CT Michaels

Christoph A Weber

2023/4/18

Spontaneous nucleation and fast aggregate-dependent proliferation of α-synuclein aggregates within liquid condensates at neutral pH

Proceedings of the National Academy of Sciences

Samuel T Dada

Maarten C Hardenberg

Zenon Toprakcioglu

Lena K Mrugalla

Mariana P Cali

...

2023/2/28

Approximate analytical solution to the Flory-Huggins model

Biophysical Journal

Daoyuan Qian

Thomas CT Michaels

Tuomas PJ Knowles

2023/2/10

Optimal intercellular competition in senescence and cancer

Proceedings of the Royal Society A

Thomas CT Michaels

L Mahadevan

2023/8/30

Aggregation controlled by condensate rheology

Biophysical Journal

Wolfram Pönisch

Thomas CT Michaels

Christoph A Weber

2023/1/3

Amyloid formation as a protein phase transition

Thomas CT Michaels

Daoyuan Qian

Anđela Šarić

Michele Vendruscolo

Sara Linse

...

2023/7

Physical limits to acceleration of chemical reactions inside phase-separated compartments

bioRxiv

Jeremy D Schmit

Thomas CT Michaels

2022/5/5

Tie-line analysis reveals interactions driving heteromolecular condensate formation

Physical Review X

Daoyuan Qian

Timothy J Welsh

Nadia A Erkamp

Seema Qamar

Jonathon Nixon-Abell

...

2022/12/30

Kinetic profiling of therapeutic strategies for inhibiting the formation of amyloid oligomers

The Journal of Chemical Physics

Thomas CT Michaels

Alexander J Dear

Samuel IA Cohen

Michele Vendruscolo

Tuomas PJ Knowles

2022/4/28

Enhanced potency of aggregation inhibitors mediated by liquid condensates

Physical Review Research

Thomas CT Michaels

Lakshminarayana Mahadevan

Christoph A Weber

2022/12/8

Analytical solution to the Flory Huggins model reveals scaling behaviour and enables quantitative interpretation of experimental data

bioRxiv

Daoyuan Qian

Thomas CT Michaels

Tuomas PJ Knowles

2022/4/23

Analytical solution to the Flory–Huggins model

The Journal of Physical Chemistry Letters

Daoyuan Qian

Thomas CT Michaels

Tuomas PJ Knowles

2022/8/17

See List of Professors in Thomas C T Michaels University(University of Cambridge)

Co-Authors

H-index: 178
Christopher Dobson

Christopher Dobson

University of Cambridge

H-index: 125
Daan Frenkel

Daan Frenkel

University of Cambridge

H-index: 114
Michele Vendruscolo

Michele Vendruscolo

University of Cambridge

H-index: 109
L Mahadevan

L Mahadevan

Harvard University

H-index: 95
Tuomas Knowles

Tuomas Knowles

University of Cambridge

H-index: 94
Ehud Gazit

Ehud Gazit

Tel Aviv University

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