Tetsushi Sakuma

About Tetsushi Sakuma

Tetsushi Sakuma, With an exceptional h-index of 47 and a recent h-index of 38 (since 2020), a distinguished researcher at Hiroshima University, specializes in the field of Genome engineering, Genome editing, TALENs, CRISPR, Cas9.

His recent articles reflect a diverse array of research interests and contributions to the field:

REMOVER-PITCh: microhomology-assisted long-range gene replacement with highly multiplexed CRISPR-Cas9

Inhibition of OCT4 binding at the MYCN locus induces neuroblastoma cell death accompanied by downregulation of transcripts with high-open reading frame dominance

Pigs with an INS point mutation derived from zygotes electroporated with CRISPR/Cas9 and ssODN

Sclerostin modulates the degree of mineralization and the stiffness profile of the fibrocartilaginous enthesis for mechanical tissue integrity

UGGT1/2-mediated reglucosylation of N-glycan competes with ER-associated degradation of unstable and misfolded glycoproteins

3D matrix adhesion feedback controls nuclear force coupling to drive invasive cell migration

Platinum Talen-Mediated Knock-in of Single-Stranded DNA Templates Facilitates Manufacturing of Clinical-Scale Non-Virally Gene-Edited T Cells from Peripheral Blood

Method for editing target dna, method for producing cell in which target dna is edited, and dna editing system for use in these

Tetsushi Sakuma Information

University

Position

Associate Professor

Citations(all)

9393

Citations(since 2020)

5544

Cited By

6469

hIndex(all)

47

hIndex(since 2020)

38

i10Index(all)

125

i10Index(since 2020)

104

Email

University Profile Page

Google Scholar

Tetsushi Sakuma Skills & Research Interests

Genome engineering

Genome editing

TALENs

CRISPR

Cas9

Top articles of Tetsushi Sakuma

REMOVER-PITCh: microhomology-assisted long-range gene replacement with highly multiplexed CRISPR-Cas9

In Vitro Cellular & Developmental Biology-Animal

2024/2/9

Tetsushi Sakuma
Tetsushi Sakuma

H-Index: 40

Takashi Yamamoto
Takashi Yamamoto

H-Index: 24

Inhibition of OCT4 binding at the MYCN locus induces neuroblastoma cell death accompanied by downregulation of transcripts with high-open reading frame dominance

Frontiers in Oncology

2024

Tetsushi Sakuma
Tetsushi Sakuma

H-Index: 40

Takashi Yamamoto
Takashi Yamamoto

H-Index: 24

Pigs with an INS point mutation derived from zygotes electroporated with CRISPR/Cas9 and ssODN

Frontiers in Cell and Developmental Biology

2023/1/13

Tetsushi Sakuma
Tetsushi Sakuma

H-Index: 40

Takashi Yamamoto
Takashi Yamamoto

H-Index: 24

Sclerostin modulates the degree of mineralization and the stiffness profile of the fibrocartilaginous enthesis for mechanical tissue integrity

bioRxiv

2023

UGGT1/2-mediated reglucosylation of N-glycan competes with ER-associated degradation of unstable and misfolded glycoproteins

bioRxiv

2023

3D matrix adhesion feedback controls nuclear force coupling to drive invasive cell migration

Cell reports

2023/12/26

Platinum Talen-Mediated Knock-in of Single-Stranded DNA Templates Facilitates Manufacturing of Clinical-Scale Non-Virally Gene-Edited T Cells from Peripheral Blood

Blood

2023/11/28

Method for editing target dna, method for producing cell in which target dna is edited, and dna editing system for use in these

2023/10/26

Full replacement technique for T cell receptor using platinum TALEN

2023/10/17

Technique for creating antigen-specific regulatory T cells (Treg) in which effector T cell (Teff) antigen receptors are used

2023/10/3

Genome editing for biodiesel production in oleaginous microalga, Nannochloropsis species

2023/8/2

Transcription activator-like effector nuclease-mediated deletion safely eliminates the major egg allergen ovomucoid in chickens

Food and Chemical Toxicology

2023/5/1

Developmental changes in brain activity of heterozygous Scn1a knockout rats

Frontiers in Neurology

2023/3/14

Robust protein-based engineering of hepatocyte-like cells from human mesenchymal stem cells

Hepatology Communications

2023/3/1

Tetsushi Sakuma
Tetsushi Sakuma

H-Index: 40

Takashi Yamamoto
Takashi Yamamoto

H-Index: 24

Development of a chub mackerel with less-aggressive fry stage by genome editing of arginine vasotocin receptor V1a2

Scientific reports

2023/2/23

Updated overview of TALEN construction systems

2023/2/12

Tetsushi Sakuma
Tetsushi Sakuma

H-Index: 40

Takashi Yamamoto
Takashi Yamamoto

H-Index: 24

Non-human primate alzheimer's disease model animal and method for producing same

2023/1/26

Polypeptide Containing DNA-Binding Domain

2022/6/14

Frame Editors for Precise, Template-Free Frameshifting

bioRxiv

2022/12/5

From nuclease-based gene knock-in to prime editing–promising technologies of precision gene engineering

Gene and Genome Editing

2022/12/1

Tetsushi Sakuma
Tetsushi Sakuma

H-Index: 40

See List of Professors in Tetsushi Sakuma University(Hiroshima University)

Co-Authors

academic-engine