Tetsushi Sakuma

Tetsushi Sakuma

Hiroshima University

H-index: 47

Asia-Japan

About Tetsushi Sakuma

Tetsushi Sakuma, With an exceptional h-index of 47 and a recent h-index of 38 (since 2020), a distinguished researcher at Hiroshima University, specializes in the field of Genome engineering, Genome editing, TALENs, CRISPR, Cas9.

His recent articles reflect a diverse array of research interests and contributions to the field:

REMOVER-PITCh: microhomology-assisted long-range gene replacement with highly multiplexed CRISPR-Cas9

Inhibition of OCT4 binding at the MYCN locus induces neuroblastoma cell death accompanied by downregulation of transcripts with high-open reading frame dominance

3D matrix adhesion feedback controls nuclear force coupling to drive invasive cell migration

Non-human primate alzheimer's disease model animal and method for producing same

Transcription activator-like effector nuclease-mediated deletion safely eliminates the major egg allergen ovomucoid in chickens

Platinum Talen-Mediated Knock-in of Single-Stranded DNA Templates Facilitates Manufacturing of Clinical-Scale Non-Virally Gene-Edited T Cells from Peripheral Blood

Pigs with an INS point mutation derived from zygotes electroporated with CRISPR/Cas9 and ssODN

Developmental changes in brain activity of heterozygous Scn1a knockout rats

Tetsushi Sakuma Information

University

Position

Associate Professor

Citations(all)

9393

Citations(since 2020)

5544

Cited By

6469

hIndex(all)

47

hIndex(since 2020)

38

i10Index(all)

125

i10Index(since 2020)

104

Email

University Profile Page

Hiroshima University

Google Scholar

View Google Scholar Profile

Tetsushi Sakuma Skills & Research Interests

Genome engineering

Genome editing

TALENs

CRISPR

Cas9

Top articles of Tetsushi Sakuma

Title

Journal

Author(s)

Publication Date

REMOVER-PITCh: microhomology-assisted long-range gene replacement with highly multiplexed CRISPR-Cas9

In Vitro Cellular & Developmental Biology-Animal

Shu Matsuzaki

Tetsushi Sakuma

Takashi Yamamoto

2024/2/9

Inhibition of OCT4 binding at the MYCN locus induces neuroblastoma cell death accompanied by downregulation of transcripts with high-open reading frame dominance

Frontiers in Oncology

Kazuma Nakatani

Hiroyuki Kogashi

Takanori Miyamoto

Taiki Setoguchi

Tetsushi Sakuma

...

2024

3D matrix adhesion feedback controls nuclear force coupling to drive invasive cell migration

Cell reports

Daniel Newman

Lorna E Young

Thomas Waring

Louise Brown

Katarzyna I Wolanska

...

2023/12/26

Non-human primate alzheimer's disease model animal and method for producing same

2023/1/26

Transcription activator-like effector nuclease-mediated deletion safely eliminates the major egg allergen ovomucoid in chickens

Food and Chemical Toxicology

Ryo Ezaki

Tetsushi Sakuma

Daisuke Kodama

Ryou Sasahara

Taichi Shiraogawa

...

2023/5/1

Platinum Talen-Mediated Knock-in of Single-Stranded DNA Templates Facilitates Manufacturing of Clinical-Scale Non-Virally Gene-Edited T Cells from Peripheral Blood

Blood

Kayo Toishigawa

Taro Edahiro

Kenta Magoori

Hiroyuki Sato

Saori Fukunaga

...

2023/11/28

Pigs with an INS point mutation derived from zygotes electroporated with CRISPR/Cas9 and ssODN

Frontiers in Cell and Developmental Biology

Fuminori Tanihara

Maki Hirata

Zhao Namula

Lanh Thi Kim Do

Naoaki Yoshimura

...

2023/1/13

Developmental changes in brain activity of heterozygous Scn1a knockout rats

Frontiers in Neurology

Mayu Tahara

Norimichi Higurashi

Junichi Hata

Masako Nishikawa

Ken Ito

...

2023/3/14

Method for editing target dna, method for producing cell in which target dna is edited, and dna editing system for use in these

2023/10/26

Sclerostin modulates the degree of mineralization and the stiffness profile of the fibrocartilaginous enthesis for mechanical tissue integrity

bioRxiv

Shinsei Yambe

Yuki Yoshimoto

Kazutaka Ikeda

Koichiro Maki

Aki Takimoto

...

2023

Robust protein-based engineering of hepatocyte-like cells from human mesenchymal stem cells

Hepatology Communications

Tomoki Takashina

Akihiro Matsunaga

Yukiko Shimizu

Tetsushi Sakuma

Tadashi Okamura

...

2023/3/1

Full replacement technique for T cell receptor using platinum TALEN

2023/10/17

UGGT1/2-mediated reglucosylation of N-glycan competes with ER-associated degradation of unstable and misfolded glycoproteins

bioRxiv

Satoshi Ninagawa

Masaki Matsuo

Deng Ying

Shinya Aso

Kazutoshi Matsushita

...

2023

Technique for creating antigen-specific regulatory T cells (Treg) in which effector T cell (Teff) antigen receptors are used

2023/10/3

Development of a chub mackerel with less-aggressive fry stage by genome editing of arginine vasotocin receptor V1a2

Scientific reports

Hirofumi Ohga

Koki Shibata

Ryo Sakanoue

Takuma Ogawa

Hajime Kitano

...

2023/2/23

Genome editing for biodiesel production in oleaginous microalga, Nannochloropsis species

Tomokazu Kurita

Masako Iwai

Hiroyuki Ohta

Tetsushi Sakuma

Takashi Yamamoto

2023/8/2

Updated overview of TALEN construction systems

Tetsushi Sakuma

Takashi Yamamoto

2023/2/12

Methods for designing dna binding protein containing ppr motifs, and use thereof

2022/3/3

Method for introducing antigen-specific receptor gene into t cell genome using cyclic dna

2022/9/21

Frame Editors for Precise, Template-Free Frameshifting

bioRxiv

Shota Nakade

Kazuki Nakamae

Tzu-Chieh Tang

Dou Yu

Tetsushi Sakuma

...

2022/12/5

See List of Professors in Tetsushi Sakuma University(Hiroshima University)

Co-Authors

H-index: 66
Kohichi Tanaka

Kohichi Tanaka

Tokyo Medical and Dental University

H-index: 54
Takashi Yamamoto

Takashi Yamamoto

Hiroshima University

H-index: 48
Toshiya Muranaka

Toshiya Muranaka

Osaka University

H-index: 40
Akitsu Hotta, Ph.D.

Akitsu Hotta, Ph.D.

Kyoto University

H-index: 37
Hidetoshi Saiga

Hidetoshi Saiga

Tokyo Metropolitan University

H-index: 36
Kazuharu Arakawa

Kazuharu Arakawa

Keio University

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