TA YUAN CHANG

TA YUAN CHANG

Dartmouth College

H-index: 66

North America-United States

About TA YUAN CHANG

TA YUAN CHANG, With an exceptional h-index of 66 and a recent h-index of 31 (since 2020), a distinguished researcher at Dartmouth College, specializes in the field of biomedical research.

His recent articles reflect a diverse array of research interests and contributions to the field:

ACAT1/SOAT1 Blockade Suppresses LPS-Mediated Neuroinflammation by Modulating the Fate of Toll-like Receptor 4 in Microglia

Acute ACAT1/SOAT1 blockade increases MAM cholesterol and strengthens ER-mitochondria connectivity

Stealth Liposomes Encapsulating a Potent ACAT1/SOAT1 Inhibitor F12511: Pharmacokinetic, Biodistribution, and Toxicity Studies in Wild-Type Mice and Efficacy Studies in Triple …

Facile method to incorporate high-affinity ACAT/SOAT1 inhibitor F12511 into stealth liposome-based nanoparticle and demonstration of its efficacy in blocking cholesteryl ester …

TGFb induces murine CXCR5 and Bcl6 and differentially specifies Tfh versus Th17 cell fates

Composition and method for attenuating neuroinflammation, amyloidopathy and tauopathy

INAUGURAL ARTICLE by a Recently Elected Academy Member: Acat1/Soat1 knockout extends the mutant Npc1 mouse lifespan and ameliorates functional deficiencies in multiple …

Acat1/Soat1 knockout extends the mutant Npc1 mouse lifespan and ameliorates functional deficiencies in multiple organelles of mutant cells

TA YUAN CHANG Information

University

Position

professor of Biochemistry, Geisel School of Medicine at Dartmouth

Citations(all)

30086

Citations(since 2020)

11153

Cited By

22799

hIndex(all)

66

hIndex(since 2020)

31

i10Index(all)

135

i10Index(since 2020)

69

Email

University Profile Page

Google Scholar

TA YUAN CHANG Skills & Research Interests

biomedical research

Top articles of TA YUAN CHANG

Title

Journal

Author(s)

Publication Date

ACAT1/SOAT1 Blockade Suppresses LPS-Mediated Neuroinflammation by Modulating the Fate of Toll-like Receptor 4 in Microglia

International Journal of Molecular Sciences

Haibo Li

Thao N Huynh

Michael Tran Duong

James Gow

Catherine C Chang

...

2022

Acute ACAT1/SOAT1 blockade increases MAM cholesterol and strengthens ER-mitochondria connectivity

International Journal of Molecular Sciences

Taylor C Harned

Radu V Stan

Ze Cao

Rajarshi Chakrabarti

Henry N Higgs

...

2023/3/14

Stealth Liposomes Encapsulating a Potent ACAT1/SOAT1 Inhibitor F12511: Pharmacokinetic, Biodistribution, and Toxicity Studies in Wild-Type Mice and Efficacy Studies in Triple …

International Journal of Molecular Sciences

Adrianna L De La Torre

Thao N Huynh

Catherine CY Chang

Darcy B Pooler

Dylan B Ness

...

2023/7/2

Facile method to incorporate high-affinity ACAT/SOAT1 inhibitor F12511 into stealth liposome-based nanoparticle and demonstration of its efficacy in blocking cholesteryl ester …

Journal of neuroscience methods

L Adrianna

Caleb Smith

Joseph Granger

Faith L Anderson

Taylor C Harned

...

2022/2/1

TGFb induces murine CXCR5 and Bcl6 and differentially specifies Tfh versus Th17 cell fates

Y Chang

L Bach

M Hasiuk

C Tsui

DT Utzschneider

...

2022

Composition and method for attenuating neuroinflammation, amyloidopathy and tauopathy

2022/8/18

INAUGURAL ARTICLE by a Recently Elected Academy Member: Acat1/Soat1 knockout extends the mutant Npc1 mouse lifespan and ameliorates functional deficiencies in multiple …

Proceedings of the National Academy of Sciences of the United States of America

Tori M Hoehler

Dylan J Mankel

Peter R Girguis

Thomas M McCollom

Nancy Y Kiang

...

2023/6/6

Acat1/Soat1 knockout extends the mutant Npc1 mouse lifespan and ameliorates functional deficiencies in multiple organelles of mutant cells

Proceedings of the National Academy of Sciences

Maximillian A Rogers

Catherine CY Chang

Robert A Maue

Elaina M Melton

Andrew A Peden

...

2022/5/3

Blocking cholesterol storage to treat Alzheimer’s disease

Exploration of neuroprotective therapy

Ta Yuan Chang

Catherine CY Chang

Taylor C Harned

L Adrianna

Junghoon Lee

...

2021/12/12

Cholesterol, atherosclerosis, and APOE in vascular contributions to cognitive impairment and dementia (VCID): potential mechanisms and therapy

Frontiers in Aging Neuroscience

Michael Tran Duong

Ilya M Nasrallah

David A Wolk

Catherine CY Chang

Ta-Yuan Chang

2021/3/25

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

Daniel J Klionsky

Amal Kamal Abdel-Aziz

Sara Abdelfatah

Mahmoud Abdellatif

Asghar Abdoli

...

2021/1/2

Nanodisc scaffold peptide (NSPr) replaces detergent by reconstituting acyl-CoA: cholesterol acyltransferase 1 into peptidiscs

Archives of biochemistry and biophysics

Bryan Neumann

Kevin Chao

Catherine CY Chang

Ta-Yuan Chang

2020/9/30

Acat1 gene KO restores TGN cholesterol deficiency in mutant NPC1 cells and expands mutant Npc1 mouse lifespan

bioRxiv

Maximillian A Rogers

Catherine CY Chang

Robert A Maue

Elaina M Melton

Andrew A Peden

...

2020/8/7

Structural insights into the inhibition mechanism of human sterol O-acyltransferase 1 by a competitive inhibitor

Nature communications

Chengcheng Guan

Yange Niu

Si-Cong Chen

Yunlu Kang

Jing-Xiang Wu

...

2020/5/18

Inhibition mechanism of human sterol O-acyltransferase 1 by competitive inhibitor

bioRxiv

Chengcheng Guan

Yange Niu

Si-Cong Chen

Yunlu Kang

Jing-Xiang Wu

...

2020/1/1

See List of Professors in TA YUAN CHANG University(Dartmouth College)