Sylvain Meloche

Sylvain Meloche

Université de Montréal

H-index: 71

North America-Canada

About Sylvain Meloche

Sylvain Meloche, With an exceptional h-index of 71 and a recent h-index of 33 (since 2020), a distinguished researcher at Université de Montréal, specializes in the field of signal transduction, MAP kinases, ubiquitin-proteasome-system, drug development, cancer.

His recent articles reflect a diverse array of research interests and contributions to the field:

Investigating the role of SRC-family kinases in MPNST tumorigenesis

OSGN-1 is a conserved flavin-containing monooxygenase required to stabilize the intercellular bridge in late cytokinesis

Phosphoproteomic analysis identifies supervillin as an ERK3 substrate regulating cytokinesis and cell ploidy

CNK2 promotes cancer cell motility by mediating ARF6 activation downstream of AXL signalling

Discovery of Benzodiazepine-Based Inhibitors of the E2 Enzyme UBCH10 from a Cell-Based p21 Degradation Screen

The G protein-coupled receptor TBXA2R activates ERMs to promote motility, invasion, and metastasis of triple-negative breast cancer cells

ERK3 Is Involved in Regulating Cardiac Fibroblast Function

A renaissance for YES in cancer

Sylvain Meloche Information

University

Position

Institute of Research in Immunology and Cancer

Citations(all)

17033

Citations(since 2020)

3563

Cited By

14746

hIndex(all)

71

hIndex(since 2020)

33

i10Index(all)

131

i10Index(since 2020)

68

Email

University Profile Page

Université de Montréal

Google Scholar

View Google Scholar Profile

Sylvain Meloche Skills & Research Interests

signal transduction

MAP kinases

ubiquitin-proteasome-system

drug development

cancer

Top articles of Sylvain Meloche

Title

Journal

Author(s)

Publication Date

Investigating the role of SRC-family kinases in MPNST tumorigenesis

Cancer Research

Elamine Zereg

Laure Voisin

Karl Grenier

Mathieu Courcelles

Sungmi Jung

...

2024/3/22

OSGN-1 is a conserved flavin-containing monooxygenase required to stabilize the intercellular bridge in late cytokinesis

Proceedings of the National Academy of Sciences

Eugénie Goupil

Léa Lacroix

Jonathan Brière

Sandra Guga

Marc K Saba-El-Leil

...

2024/3/12

Phosphoproteomic analysis identifies supervillin as an ERK3 substrate regulating cytokinesis and cell ploidy

Journal of Cellular Physiology

Joaquim Javary

Eugénie Goupil

Mathilde Soulez

Evgeny Kanshin

Antoine Bouchard

...

2024/3

CNK2 promotes cancer cell motility by mediating ARF6 activation downstream of AXL signalling

Nature Communications

Guillaume Serwe

David Kachaner

Jessica Gagnon

Cédric Plutoni

Driss Lajoie

...

2023/6/15

Discovery of Benzodiazepine-Based Inhibitors of the E2 Enzyme UBCH10 from a Cell-Based p21 Degradation Screen

ACS Chemical Biology

Benoit Pelletier

Stéphanie Duhamel

Guillaume Tambutet

Scott Jarvis

Patrick Cléroux

...

2023/4/25

The G protein-coupled receptor TBXA2R activates ERMs to promote motility, invasion, and metastasis of triple-negative breast cancer cells

bioRxiv

Kévin Leguay

Omaima Naffati

Yu Yan He

Mireille Hogue

Chloé Tesnière

...

2023/3/29

ERK3 Is Involved in Regulating Cardiac Fibroblast Function

bioRxiv

Pramod Sahadevan

Dharmendra Dingar

Sherin A Nawaito

Reshma S Nair

Joëlle Trépanier

...

2023

A renaissance for YES in cancer

Marjorie Lapouge

Sylvain Meloche

2023/11/10

CDK12 is hyperactivated and a synthetic-lethal target in BRAF-mutated melanoma

Nature Communications

Thibault Houles

Geneviève Lavoie

Sami Nourreddine

Winnie Cheung

Éric Vaillancourt-Jean

...

2022/10/29

Development of a high-throughput assay to identify inhibitors of the ubiquitin-conjugating enzyme UBCH10

SLAS Discovery

Patrick Cléroux

Laure Voisin

Sylvain Meloche

2022/6/1

ERK3‐MK5 signaling regulates myogenic differentiation and muscle regeneration by promoting FoxO3 degradation

Journal of Cellular Physiology

Mathilde Soulez

Pierre‐Luc Tanguay

Florence Dô

Junio Dort

Colin Crist

...

2022/4

Signaling by the tyrosine kinase Yes promotes liver cancer development

Science Signaling

Jean-Philippe Guégan

Marjorie Lapouge

Laure Voisin

Marc K Saba-El-Leil

Pierre-Luc Tanguay

...

2022/1/18

YES, a novel therapeutic target in hepatocellular carcinoma

Molecular & Cellular Oncology

Marjorie Lapouge

Sylvain Meloche

2022/12/31

On the Therapeutic Potential of ERK4 in Triple-Negative Breast Cancer

Cancers

Fadia Boudghene-Stambouli

Mathilde Soulez

Natalia Ronkina

Anneke Dörrie

Alexey Kotlyarov

...

2022/12/21

Interleukin-17 receptor D in physiology, inflammation and cancer

Charlotte Girondel

Sylvain Meloche

2021/3/23

Loss of interleukin-17 receptor D promotes chronic inflammation-associated tumorigenesis

Oncogene

Charlotte Girondel

Kim Lévesque

Marie-Josée Langlois

Sarah Pasquin

Marc K Saba-El-Leil

...

2021/1/14

Regulation of mitogen-activated protein kinase signaling pathways by the ubiquitin-proteasome system and its pharmacological potential

Andrea M Cooper

Aluicia Anita Artarini

Sophi Damayanti

Elin Yulinah Sukandar

Dian Ayu Eka Pitaloka

2020/8/28

ERK4-deficiency Potentiates the TAC-induced Increase in Collagen1-α1 Messenger RNA in Mice

Circulation Research

Joelle Trepanier

Dharmendra D Dingar

Marc-Antoine Gillis

Pramod Sahadevan

Yan Fen Shi

...

2020/7/31

Copper bioavailability is a KRAS-specific vulnerability in colorectal cancer

Nature communications

Léo Aubert

Neethi Nandagopal

Zachary Steinhart

Geneviève Lavoie

Sami Nourreddine

...

2020/7/24

See List of Professors in Sylvain Meloche University(Université de Montréal)