Susan Michaelis

Susan Michaelis

Johns Hopkins University

H-index: 60

North America-United States

About Susan Michaelis

Susan Michaelis, With an exceptional h-index of 60 and a recent h-index of 24 (since 2020), a distinguished researcher at Johns Hopkins University, specializes in the field of yeast, Saccharomyces cerevisiae, progeria, zmpste24, quality control.

His recent articles reflect a diverse array of research interests and contributions to the field:

Analysis of a degron-containing reporter protein GFP-CL1 reveals a role for SUMO1 in cytosolic protein quality control

The farnesyl transferase inhibitor (FTI) lonafarnib improves nuclear morphology in ZMPSTE24-deficient fibroblasts from patients with the progeroid disorder MAD-B

Prelamin A and ZMPSTE24 in premature and physiological aging

The integral membrane protein ZMPSTE24 protects cells from SARS-CoV-2 spike-mediated pseudovirus infection and syncytia formation

Abolishing the prelamin A ZMPSTE24 cleavage site leads to progeroid phenotypes with near-normal longevity in mice

Site specificity determinants for prelamin A cleavage by the zinc metalloprotease ZMPSTE24

Cleavage Site Specificity for Processing of Farnesylated Prelamin A by the Zinc Metalloprotease ZMPSTE24

A new paradigm for Prelamin A proteolytic processing by ZMPSTE24: the upstream SY^ LL cleavage occurs first and there is no CaaX processing by ZMPSTE24

Susan Michaelis Information

University

Position

The Johns Hopkins School of Medicine

Citations(all)

14609

Citations(since 2020)

2031

Cited By

13165

hIndex(all)

60

hIndex(since 2020)

24

i10Index(all)

85

i10Index(since 2020)

49

Email

University Profile Page

Johns Hopkins University

Google Scholar

View Google Scholar Profile

Susan Michaelis Skills & Research Interests

yeast

Saccharomyces cerevisiae

progeria

zmpste24

quality control

Top articles of Susan Michaelis

Title

Journal

Author(s)

Publication Date

Analysis of a degron-containing reporter protein GFP-CL1 reveals a role for SUMO1 in cytosolic protein quality control

Journal of Biological Chemistry

Wei Wang

Jian Lu

Wei-Chih Yang

Eric D Spear

Susan Michaelis

...

2023/2/1

The farnesyl transferase inhibitor (FTI) lonafarnib improves nuclear morphology in ZMPSTE24-deficient fibroblasts from patients with the progeroid disorder MAD-B

Nucleus

Kamsi O Odinammadu

Khurts Shilagardi

Kelsey Tuminelli

Daniel P Judge

Leslie B Gordon

...

2023/12/31

Prelamin A and ZMPSTE24 in premature and physiological aging

Howard J Worman

Susan Michaelis

2023/12/31

The integral membrane protein ZMPSTE24 protects cells from SARS-CoV-2 spike-mediated pseudovirus infection and syncytia formation

MBio

Khurts Shilagardi

Eric D Spear

Rachy Abraham

Diane E Griffin

Susan Michaelis

2022/10/26

Abolishing the prelamin A ZMPSTE24 cleavage site leads to progeroid phenotypes with near-normal longevity in mice

Proceedings of the National Academy of Sciences

Yuexia Wang

Khurts Shilagardi

Trunee Hsu

Kamsi O Odinammadu

Takamitsu Maruyama

...

2022/3/1

Site specificity determinants for prelamin A cleavage by the zinc metalloprotease ZMPSTE24

Journal of Biological Chemistry

Timothy D Babatz

Eric D Spear

Wenxin Xu

Olivia L Sun

Laiyin Nie

...

2021/1/1

Cleavage Site Specificity for Processing of Farnesylated Prelamin A by the Zinc Metalloprotease ZMPSTE24

bioRxiv

Timothy D Babatz

Eric D Spear

Wenxin Xu

Olivia L Sun

Laiyin Nie

...

2020/8/17

A new paradigm for Prelamin A proteolytic processing by ZMPSTE24: the upstream SY^ LL cleavage occurs first and there is no CaaX processing by ZMPSTE24

bioRxiv

Laiyin Nie

Eric Spear

Timothy D Babatz

Andrew Quigley

Yin Yao Dong

...

2020/5/13

Defining substrate requirements for cleavage of farnesylated prelamin A by the integral membrane zinc metalloprotease ZMPSTE24

PloS one

Kaitlin M Wood

Eric D Spear

Otto W Mossberg

Kamsi O Odinammadu

Wenxin Xu

...

2020/12/14

See List of Professors in Susan Michaelis University(Johns Hopkins University)