Stephen Sligar

Stephen Sligar

University of Illinois at Urbana-Champaign

H-index: 115

North America-United States

About Stephen Sligar

Stephen Sligar, With an exceptional h-index of 115 and a recent h-index of 40 (since 2020), a distinguished researcher at University of Illinois at Urbana-Champaign, specializes in the field of Chemistry, Biochemistry, Molecular Biology.

His recent articles reflect a diverse array of research interests and contributions to the field:

Engineering C–C bond cleavage activity into a P450 monooxygenase enzyme

Revealing KRas4b topology on the membrane surface

Tsuneo Omura-In memory of a Pioneer in cytochrome P450 research.

Solvent isotope effects in the catalytic cycle of P450 CYP17A1: Computational modeling of the hydroxylation and lyase reactions

Midazolam as a probe for heterotropic drug-drug interactions mediated by CYP3A4

Importance of Asparagine 202 in manipulating active site structure and substrate preference for human CYP17A1

Midazolam as a probe for drug–drug interactions mediated by cyp3a4: homotropic allosteric mechanism of site-specific hydroxylation

Substrate-Specific Allosteric Effects on the Enhancement of CYP17A1 Lyase Efficiency by Cytochrome b5

Stephen Sligar Information

University

Position

Professor

Citations(all)

51595

Citations(since 2020)

9860

Cited By

45387

hIndex(all)

115

hIndex(since 2020)

40

i10Index(all)

395

i10Index(since 2020)

174

Email

University Profile Page

University of Illinois at Urbana-Champaign

Google Scholar

View Google Scholar Profile

Stephen Sligar Skills & Research Interests

Chemistry

Biochemistry

Molecular Biology

Top articles of Stephen Sligar

Title

Journal

Author(s)

Publication Date

Engineering C–C bond cleavage activity into a P450 monooxygenase enzyme

Journal of the American Chemical Society

Justin C Miller

Joel HZ Lee

Mark A Mclean

Rebecca R Chao

Isobella SJ Stone

...

2023/4/12

Revealing KRas4b topology on the membrane surface

Biochemical and Biophysical Research Communications

Shweta Shree

Mark A McLean

Andrew G Stephen

Stephen G Sligar

2023/10/20

Tsuneo Omura-In memory of a Pioneer in cytochrome P450 research.

Journal of Inorganic Biochemistry

John H Dawson

Stephen G Sligar

2023/7/26

Solvent isotope effects in the catalytic cycle of P450 CYP17A1: Computational modeling of the hydroxylation and lyase reactions

Journal of Inorganic Biochemistry

Ilia G Denisov

Stephen G Sligar

2023/6/1

Midazolam as a probe for heterotropic drug-drug interactions mediated by CYP3A4

Biomolecules

Ilia G Denisov

Yelena V Grinkova

Mark A McLean

Tyler Camp

Stephen G Sligar

2022/6/20

Importance of Asparagine 202 in manipulating active site structure and substrate preference for human CYP17A1

Biochemistry

Yilin Liu

Ilia Denisov

Michael Gregory

Stephen G Sligar

James R Kincaid

2022/3/15

Midazolam as a probe for drug–drug interactions mediated by cyp3a4: homotropic allosteric mechanism of site-specific hydroxylation

Biochemistry

Ilia G Denisov

Yelena V Grinkova

Tyler Camp

Mark A McLean

Stephen G Sligar

2021/5/20

Substrate-Specific Allosteric Effects on the Enhancement of CYP17A1 Lyase Efficiency by Cytochrome b5

Journal of the American Chemical Society

Yilin Liu

Ilia G Denisov

Stephen G Sligar

James R Kincaid

2021/3/3

Nanodiscs: A toolkit for membrane protein science

Stephen G Sligar

Ilia G Denisov

2021/2

Mechanism of the clinically relevant E305G mutation in human P450 CYP17A1

Biochemistry

Yilin Liu

Yelena Grinkova

Michael C Gregory

Ilia G Denisov

James R Kincaid

...

2021/10/18

Biomimetic chemical sensors using nanoelectronic readout of olfactory receptors

2021/1/26

Cryoradiolysis of oxygenated cytochrome P450 17A1 with lyase substrates generates expected products

Remigio Usai

Ilia Denisov

Stephen Sligar

James Kincaid

2021/9/13

A Pathfinder in High-Pressure Bioscience: In Memoriam of Gaston Hui Bon Hoa

Dmitri R Davydov

Christiane Jung

Gregory A Petsko

Stephen G Sligar

Jack A Kornblatt

2021/8/16

Dark, ultra-dark and ultra-bright nanodiscs for membrane protein investigations

Analytical biochemistry

Mark A McLean

Ilia G Denisov

Yelena V Grinkova

Stephen G Sligar

2020/10/15

Nanodisc self-assembly is thermodynamically reversible and controllable

Soft Matter

Tyler Camp

Stephen G Sligar

2020

A modified vilsmeier–haack strategy to construct β-pyridine-fused 5, 10, 15, 20-tetraarylporphyrins

SynOpen

Pargat Singh

Mahendra Nath

2020/4

Membrane-bound Ras as a conformational clock

Biophysical journal

Alemayehu A Gorfe

Stephen G Sligar

2020/3/10

The Thermodynamic Landscape of Nanodisc Self-Assembly

Biophysical Journal

Tyler Camp

Stephen G Sligar

2020/2/7

Antibody Targeted PET Imaging of 64Cu-DOTA-Anti-CEA PEGylated Lipid Nanodiscs in CEA Positive Tumors

Bioconjugate chemistry

Patty Wong

Lin Li

Junie Chea

Weidong Hu

Erasmus Poku

...

2020/1/21

P450 CYP17A1 variant with a disordered proton shuttle assembly retains peroxo‐mediated lyase efficiency

Chemistry–A European Journal

Yilin Liu

Ilia G Denisov

Yelena V Grinkova

Stephen G Sligar

James R Kincaid

2020/12/15

See List of Professors in Stephen Sligar University(University of Illinois at Urbana-Champaign)

Co-Authors

H-index: 173
Klaus Schulten

Klaus Schulten

University of Illinois at Urbana-Champaign

H-index: 98
Thomas L. Poulos

Thomas L. Poulos

University of California, Irvine

H-index: 62
Paul M. Champion

Paul M. Champion

North Eastern University

H-index: 62
Paul Bohn

Paul Bohn

University of Notre Dame

H-index: 58
John H Dawson

John H Dawson

University of South Carolina

academic-engine