Stephen H. Tsang

Stephen H. Tsang

Columbia University in the City of New York

H-index: 65

North America-United States

About Stephen H. Tsang

Stephen H. Tsang, With an exceptional h-index of 65 and a recent h-index of 45 (since 2020), a distinguished researcher at Columbia University in the City of New York, specializes in the field of genome editing, retinal degeneration.

His recent articles reflect a diverse array of research interests and contributions to the field:

CRISPR editing of anti-anemia drug target rescues independent preclinical models of retinitis pigmentosa

RBP3-Retinopathy—Inherited High Myopia and Retinal Dystrophy: Genetic Characterization, Natural History, and Deep Phenotyping

Methods and compositions to regulate cholesterol efflux to prevent, treat, or cure macular degeneration

Rescue strategies for best1 loss-and gain-of-function mutations

Bypassing pre-existing antibodies extends the applicability of AAV-based retinal therapies

Insights Into PROM1-Macular Disease Using Multimodal Imaging

HIF2α activation and mitochondrial deficit due to iron chelation cause retinal atrophy

Correction: Renormalization of metabolic coupling treats age-related degenerative disorders: an oxidative RPE niche fuels the more glycolytic photoreceptors

Stephen H. Tsang Information

University

Position

___

Citations(all)

16239

Citations(since 2020)

9414

Cited By

10673

hIndex(all)

65

hIndex(since 2020)

45

i10Index(all)

296

i10Index(since 2020)

252

Email

University Profile Page

Columbia University in the City of New York

Google Scholar

View Google Scholar Profile

Stephen H. Tsang Skills & Research Interests

genome editing

retinal degeneration

Top articles of Stephen H. Tsang

Title

Journal

Author(s)

Publication Date

CRISPR editing of anti-anemia drug target rescues independent preclinical models of retinitis pigmentosa

Cell Reports Medicine

Nicholas D Nolan

Xuan Cui

Brian M Robbings

Aykut Demirkol

Kriti Pandey

...

2024/4/16

RBP3-Retinopathy—Inherited High Myopia and Retinal Dystrophy: Genetic Characterization, Natural History, and Deep Phenotyping

American Journal of Ophthalmology

Michalis Georgiou

Kaoru Fujinami

Anthony G Robson

Yu Fujinami-Yokokawa

Ahmed F Shakarchi

...

2024/2/1

Methods and compositions to regulate cholesterol efflux to prevent, treat, or cure macular degeneration

2024/2/15

Rescue strategies for best1 loss-and gain-of-function mutations

2024/2/8

Bypassing pre-existing antibodies extends the applicability of AAV-based retinal therapies

Molecular Therapy

Hannah F Hu

Stephen H Tsang

2023/12/6

Insights Into PROM1-Macular Disease Using Multimodal Imaging

Investigative Ophthalmology & Visual Science

Maarjaliis Paavo

Winston Lee

Rait Parmann

Jose Ronaldo Lima de Carvalho

Jana Zernant

...

2023/4/3

HIF2α activation and mitochondrial deficit due to iron chelation cause retinal atrophy

EMBO Molecular Medicine

Yang Kong

Pei‐Kang Liu

Yao Li

Nicholas D Nolan

Peter MJ Quinn

...

2023/2/8

Correction: Renormalization of metabolic coupling treats age-related degenerative disorders: an oxidative RPE niche fuels the more glycolytic photoreceptors

Eye

Nicholas D Nolan

Salvatore Marco Caruso

Xuan Cui

Stephen H Tsang

2023/6

Development of a Prime Editing Strategy to Treat Mutations in the Crumbs Homologue 1 (CRB1) Gene

Investigative Ophthalmology & Visual Science

Bruna Lopes Costa

Alexander A Sousa

Yi-Ting Tsai

Yao Li

Irene H Maumenee

...

2023/6/1

Analysis of CRB1 Pathogenic Variants Correctable with CRISPR Base and Prime Editing

Bruna Lopes da Costa

Laura A Jenny

Irene H Maumenee

Stephen H Tsang

Peter MJ Quinn

2023/7/14

Rod Photoreceptor-Specific Ablation of Metformin Target, AMPK, in a Preclinical Model of Autosomal Recessive Retinitis Pigmentosa

Nicholas D Nolan

Laura A Jenny

Stephen H Tsang

Xuan Cui

2023/7/14

A new preclinical model of retinitis pigmentosa due to Pde6g deficiency

Ophthalmology Science

Michelle Carmen Jentzsch

Stephen H Tsang

Susanne Friederike Koch

2023/12/1

A novel pathogenic CRB1 variant presenting as Leber Congenital Amaurosis 8 and evaluation of gene editing feasibility

Documenta Ophthalmologica

Mohamed M Sylla

Masha Kolesinkova

Bruna Lopes da Costa

Irene H Maumenee

Stephen H Tsang

...

2023/12

Trap1 is expressed in human retinal pigment epithelial cells and is required to maintain their energetic status

Antioxidants

Inês Ramos Rego

Daniela Silvério

Maria Isabel Eufrásio

Sandra Sofia Pinhanços

Bruna Lopes da Costa

...

2023/2/4

Effects of medications on hypoxia‐inducible factor in the retina: A review

Angela H Kim

Masha Kolesnikova

Wei Kiong Ngo

Stephen H Tsang

2023/4

CRISPR editing demonstrates rs10490924 raised oxidative stress in iPSC-derived retinal cells from patients with ARMS2/HTRA1-related AMD

Proceedings of the National Academy of Sciences

Ya-Ju Chang

Laura A Jenny

Yong-Shi Li

Xuan Cui

Yang Kong

...

2023/5/9

Prime Editing Rescues Aberrant Splicing Defect Caused by Pathogenic Variants in PRPH2

Investigative Ophthalmology & Visual Science

Peter MJ Quinn

Yi-Ting Tsai

Salvatore Marco Caruso

Siyuan Liu

Yao Li

...

2023/6/1

Prime Editing Strategy to Install the PRPH2 c. 828+ 1G> A Mutation Salvatore Marco Caruso, Yi-Ting Tsai, Bruna Lopes da Costa, Masha Kolesnikova

Retinal Degenerative Diseases XIX: Mechanisms and Experimental Therapy

Laura A Jenny

Stephen H Tsang

Peter MJ Quinn

2023/7/13

A Unique Presentation of Bilateral Chorioretinal Atrophy

The Asia-Pacific Journal of Ophthalmology

Andrea Grosso

Lawrence A Yannuzzi

Stephen H Tsang

Piero Ceruti

David Sarraf

...

2023/9/1

Generation of CRB1 RP Patient-Derived iPSCs and a CRISPR/Cas9-Mediated Homology-Directed Repair Strategy for the CRB1 c.2480G>T Mutation

Bruna Lopes da Costa

Yao Li

Sarah R Levi

Stephen H Tsang

Peter MJ Quinn

2023/7/14

See List of Professors in Stephen H. Tsang University(Columbia University in the City of New York)