Stefani Spranger
Massachusetts Institute of Technology
H-index: 44
North America-United States
Top articles of Stefani Spranger
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
A prime editor mouse to model a broad spectrum of somatic mutations in vivo | Nature biotechnology | Zackery A Ely Nicolas Mathey-Andrews Santiago Naranjo Samuel I Gould Kim L Mercer | 2024/3 |
Abstract B087: Mutant-p53 amplifies Cxcl1 expression from distal enhancers blunting immune checkpoint inhibition efficacy in pancreatic cancer | Cancer Research | Dig B Mahat Heena Kumra Emily Metcalf Sarah Castro Kim Nguyen1 | 2024/1/16 |
Beta-catenin inhibitors in cancer immunotherapy | 2024/4/2 | ||
Something old, something new: The marriage of PD-1 and IL-2 | Immunity | Brendan L Horton Stefani Spranger | 2023/1/10 |
Both intratumoral regulatory T cell depletion and CTLA-4 antagonism are required for maximum efficacy of anti-CTLA-4 antibodies | Proceedings of the National Academy of Sciences | Brianna M Lax Joseph R Palmeri Emi A Lutz Allison Sheen Jordan A Stinson | 2023/8/1 |
1517 Mutant-p53 amplifies Cxcl1 expression from distal enhancers blunting immune checkpoint inhibition efficacy in pancreatic cancer | Dig Bijay Mahat Heena Kumra Emily Metcalf Sarah Castro Kim Nguyen | 2023/11/1 | |
Lung cancer-intrinsic SOX2 expression mediates resistance to checkpoint blockade therapy by inducing Treg-dependent CD8+ T cell exclusion | bioRxiv | Elen Torres-Mejia Sally Weng Kim Bich Nguyen Ellen Duong Leon Yim | 2023 |
Engineering kinetics of TLR7/8 agonist release from bottlebrush prodrugs enables tumor-focused immune stimulation | Science Advances | Sachin H Bhagchandani Farrukh Vohidov Lauren E Milling Evelyn Yuzhou Tong Christopher M Brown | 2023/4/19 |
1011 The signal strength of signal 2 and 3 during T cell priming affect the functional fate of an anti-tumor T cell response | Teresa Dinter Duncan Morgan Vidit Bhandarkar Lorelai Pop Emi A Lutz | 2023/11/1 | |
Differentiation and Expansion of Tumor-Infiltrating T Cell Clonotypes Occurs in the Spleen Following Immune Checkpoint Blockade | bioRxiv | Duncan M Morgan Brendan L Horton Maria Zagorulya J Christopher Love Stefani Spranger | 2023 |
MHC-dressing on dendritic cells: Boosting anti-tumor immunity via unconventional tumor antigen presentation | Fiona Chatterjee Stefani Spranger | 2023/3/1 | |
568 Tumor-intrinsic Sox2 signaling induces regulatory T cell-mediated CD8 T cell exclusion, promoting resistance to checkpoint blockade therapy in lung cancer | Elen Torres Sally Weng Kim Nguyen Ellen Duong Leon Yim | 2023/11/1 | |
Transforming ovarian cancer care by targeting minimal residual disease | Med | Amir A Jazaeri Rachel Grisham Anne Knisely Stefani Spranger Dmitriy Zamarin | 2023/11/10 |
Tissue-specific abundance of interferon-gamma drives regulatory T cells to restrain DC1-mediated priming of cytotoxic T cells against lung cancer | Immunity | Maria Zagorulya Leon Yim Duncan M Morgan Austin Edwards Elen Torres-Mejia | 2023/2/14 |
Overcoming lung cancer immunotherapy resistance by combining nontoxic variants of IL-12 and IL-2 | JCI insight | Brendan L Horton Alicia D D’Souza Maria Zagorulya Chloe V McCreery Gita C Abhiraman | 2023/10/10 |
929 Mutual interactions between neoantigen-specific CD8+ T cell responses facilitate immune evasion in sub-clonal tumors | Malte Roerden Noora Harake Byungji Kim Yufei Cui Forest White | 2023/11/1 | |
Once upon a prime: DCs shape cancer immunity | Maria Zagorulya Stefani Spranger | 2023/2/1 | |
Decoupled neoantigen cross-presentation by dendritic cells limits anti-tumor immunity against tumors with heterogeneous neoantigen expression | Elife | Kim Bich Nguyen Malte Roerden Christopher J Copeland Coralie M Backlund Nory G Klop-Packel | 2023/8/7 |
947 The activation states of tumor-resident type 2 dendritic cells impact the strength of ovarian cancer immune responses | Fiona Chatterjee Vincent Butty Emi A Lutz K Dane Wittrup Stefani Spranger | 2023/11/1 | |
129 Platform to conditionally induce lung tumors in genetically engineered mouse models using Cre mRNA containing nanoparticles | Vidit Bhandarkar Elen Torres-Mejia Namita Nabar Tamara Dacoba Paula Hammond | 2022/11/1 |
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