Simon Hirota

Simon Hirota

University of Calgary

H-index: 34

North America-Canada

About Simon Hirota

Simon Hirota, With an exceptional h-index of 34 and a recent h-index of 25 (since 2020), a distinguished researcher at University of Calgary, specializes in the field of Crohn's disease, ulcerative colitis, fibrosis, commensal microbiota, microbiota-derived metabolites.

His recent articles reflect a diverse array of research interests and contributions to the field:

A56 EVALUATING THE DYNAMICS OF CYP3A11 AND REG3G MODULATION BY IL-22

A62 EXAMINING THE ACTIVATION OF XENOBIOTIC RECEPTORS PXR AND AHR IN COLONOIDS USING MICROBIAL METABOLITES AND CHEMICAL LIGANDS

P107 Comparing the Colonic Tissue Proteome of Active and Inactive Ulcerative Colitis

Investigating the interaction between the intestinal epithelium and group-3 innate lymphoid cells in response to Clostridioides difficile toxins

A38 INVESTIGATION OF POST-TRANSLATIONAL MODIFICATIONS IN SERUM OF CROHN’S DISEASE PATIENTS USING A PROTEOMICS APPROACH

New concepts of the interplay between the gut microbiota and the enteric nervous system in the control of motility

The pregnane X receptor and indole-3-propionic acid shape the intestinal mesenchyme to restrain inflammation and fibrosis

Xenobiotic receptors and the regulation of intestinal homeostasis: harnessing the chemical output of the intestinal microbiota

Simon Hirota Information

University

Position

Associate Professor Dept. of Physiology & Pharmacology

Citations(all)

5862

Citations(since 2020)

2795

Cited By

4044

hIndex(all)

34

hIndex(since 2020)

25

i10Index(all)

59

i10Index(since 2020)

47

Email

University Profile Page

University of Calgary

Google Scholar

View Google Scholar Profile

Simon Hirota Skills & Research Interests

Crohn's disease

ulcerative colitis

fibrosis

commensal microbiota

microbiota-derived metabolites

Top articles of Simon Hirota

Title

Journal

Author(s)

Publication Date

A56 EVALUATING THE DYNAMICS OF CYP3A11 AND REG3G MODULATION BY IL-22

Journal of the Canadian Association of Gastroenterology

A Delanne-Cuménal

K Flannigan

S Hirota

2024/3/1

A62 EXAMINING THE ACTIVATION OF XENOBIOTIC RECEPTORS PXR AND AHR IN COLONOIDS USING MICROBIAL METABOLITES AND CHEMICAL LIGANDS

Journal of the Canadian Association of Gastroenterology

Eva I Shenoda

Simon A Hirota

2024/3

P107 Comparing the Colonic Tissue Proteome of Active and Inactive Ulcerative Colitis

Journal of Crohn's and Colitis

R Penner

L de Almeida

R Rosentreter

S Hirota

A Dufour

...

2024/1/1

Investigating the interaction between the intestinal epithelium and group-3 innate lymphoid cells in response to Clostridioides difficile toxins

Lauren Smith

Simon Hirota

Wallace MacNaughton

2023/5/23

A38 INVESTIGATION OF POST-TRANSLATIONAL MODIFICATIONS IN SERUM OF CROHN’S DISEASE PATIENTS USING A PROTEOMICS APPROACH

Journal of the Canadian Association of Gastroenterology

LGN De Almeida

R Rosentreter

S Hirota

C Lu

A Dufour

2023/3

New concepts of the interplay between the gut microbiota and the enteric nervous system in the control of motility

Fernando A Vicentini

Tanner Fahlman

Stephanie G Raptis

Laurie E Wallace

Simon A Hirota

...

2023/1/1

The pregnane X receptor and indole-3-propionic acid shape the intestinal mesenchyme to restrain inflammation and fibrosis

Cellular and molecular gastroenterology and hepatology

Kyle L Flannigan

Kristoff M Nieves

Holly E Szczepanski

Alex Serra

Joshua W Lee

...

2023/1/1

Xenobiotic receptors and the regulation of intestinal homeostasis: harnessing the chemical output of the intestinal microbiota

Kristoff M Nieves

Simon A Hirota

Kyle L Flannigan

2022/2/1

NR4A1 modulates intestinal smooth muscle cell phenotype and dampens inflammation‐associated intestinal remodeling

The FASEB Journal

Holly E Szczepanski

Kyle L Flannigan

Barbara Mainoli

Laurie Alston

Grace M Baruta

...

2022/11

Association of circulating fibrocytes with fibrostenotic small Bowel Crohn’s disease

Inflammatory bowel diseases

Aito Ueno

Humberto B Jijon

Richard Peng

Steven Sparksman

Barbara Mainoli

...

2022/2/1

Colitis-associated microbiota drives changes in behaviour in male mice in the absence of inflammation

Brain, Behavior, and Immunity

Fernando A Vicentini

Jake C Szamosi

Laura Rossi

Lateece Griffin

Kristoff Nieves

...

2022/5/1

Recruitment of α4β7 monocytes and neutrophils to the brain in experimental colitis is associated with elevated cytokines and anxiety-like behavior

Journal of Neuroinflammation

Nina L Cluny

Kewir D Nyuyki

Wagdi Almishri

Lateece Griffin

Benjamin H Lee

...

2022/4/4

A12 STEPWISE COORDINATION OF COLONIC NEUTROPHILS AND INNATE LYMPHOID CELLS IN THE ONSET AND RESOLUTION OF CLOSTRIDIOIDES DIFFICILE TOXIN-INDUCED INJURY

Journal of the Canadian Association of Gastroenterology

KL Flannigan

A Serra

SA Hirota

2022/3/1

A20 INTESTINAL SMOOTH MUSCLE AND FIBROSTENOSIS: TARGETING NR4A1 TO MODULATE PROLIFERATIVE SIGNALLING

Journal of the Canadian Association of Gastroenterology

J Lee

HE Szczepanski

KL Flannigan

SA Hirota

2022/3/1

Protoporphyrin IX derived from dual-species anaerobic biofilms of Fusobacterium necrophorum and Porphyromonas levii attenuates bovine neutrophil function

Biofilm

Joey S Lockhart

Thibault Allain

Simon A Hirota

Andre G Buret

Douglas W Morck

2022/12/1

Metformin prevents hyperglycemia-associated, oxidative stress-induced vascular endothelial dysfunction: essential role for the orphan nuclear receptor human nuclear receptor …

Molecular Pharmacology

Vivek Krishna Pulakazhi Venu

Mahmoud Saifeddine

Koichiro Mihara

Muniba Faiza

Evgueni Gorobets

...

2021/11/1

A37 EXPLORING THE PROTEOMICS DIFFERENCES IN CROHN’S DISEASE PATIENTS

Journal of the Canadian Association of Gastroenterology

L Nogueira de Almeida

B Mainoli

AK Filyk

SA Hirota

C Lu

...

2021/3/1

Nr4A1 modulates inflammation-associated intestinal fibrosis and dampens fibrogenic signaling in myofibroblasts

American Journal of Physiology-Gastrointestinal and Liver Physiology

Vivek Krishna Pulakazhi Venu

Laurie Alston

Mircea Iftinca

Yi-Cheng Tsai

Matthew Stephens

...

2021/9/1

A201 UNDERSTANDING THE INFECTION DYNAMICS OF MYCOBACTERIUM PARATUBERCULOSIS (MAP)

Journal of the Canadian Association of Gastroenterology

GM Baruta

H Zhang

L Alston

SA Hirota

2021/3/1

Su483 SERUM PROTEOMICS IDENTIFIES UNIQUE SIGNATURE TO DIFFERENTIATE FIBROSTENOTIC AND INFLAMMATORY CROHN'S DISEASE.

Gastroenterology

Alexis K Filyk

Barbara Mainoli

Luiz de Almeida

Simon Hirota

Antoine Dufour

...

2021/5/1

See List of Professors in Simon Hirota University(University of Calgary)

Co-Authors

H-index: 98
Subrata Ghosh

Subrata Ghosh

University of Birmingham

H-index: 98
Morley Hollenberg

Morley Hollenberg

University of Calgary

H-index: 88
Keith Sharkey

Keith Sharkey

University of Calgary

H-index: 73
Quentin Pittman

Quentin Pittman

University of Calgary

H-index: 72
Paul L. Beck

Paul L. Beck

University of Calgary

H-index: 58
Chris R Triggle

Chris R Triggle

Cornell University

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