Silvia Osuna

Silvia Osuna

Universidad de Gerona

H-index: 41

Europe-Spain

About Silvia Osuna

Silvia Osuna, With an exceptional h-index of 41 and a recent h-index of 29 (since 2020), a distinguished researcher at Universidad de Gerona, specializes in the field of Computational Chemistry.

His recent articles reflect a diverse array of research interests and contributions to the field:

Fatty acid synthase (FASN) signalome: A molecular guide for precision oncology

Harnessing Conformational Dynamics in Enzyme Catalysis to achieve Nature-like catalytic efficiencies: The Shortest Path Map tool for computational enzyme design

The shortest path method (SPM) webserver for computational enzyme design

Computational Enzyme Design

Controlling Monoterpene Isomerization by Guiding Challenging Carbocation Rearrangement Reactions in Engineered Squalene‐Hopene Cyclases

Engineering of conserved sequence motif 1 residues in halohydrin dehalogenase HheC simultaneously enhances activity, stability and enantioselectivity

Origin Of Evolutionary Bifurcation In An Enzyme

AlphaFold2 and Deep Learning for Elucidating Enzyme Conformational Flexibility and Its Application for Design

Silvia Osuna Information

University

Position

___

Citations(all)

4967

Citations(since 2020)

2910

Cited By

2999

hIndex(all)

41

hIndex(since 2020)

29

i10Index(all)

81

i10Index(since 2020)

67

Email

University Profile Page

Universidad de Gerona

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Silvia Osuna Skills & Research Interests

Computational Chemistry

Top articles of Silvia Osuna

Title

Journal

Author(s)

Publication Date

Fatty acid synthase (FASN) signalome: A molecular guide for precision oncology

Molecular Oncology

Javier A Menendez

Elisabet Cuyàs

Jose Antonio Encinar

Travis Vander Steen

Sara Verdura

...

2024/1/18

Harnessing Conformational Dynamics in Enzyme Catalysis to achieve Nature-like catalytic efficiencies: The Shortest Path Map tool for computational enzyme design

Faraday Discussions

Cristina Duran

Guillem Casadevall

Sílvia Osuna

2024

The shortest path method (SPM) webserver for computational enzyme design

Protein Engineering, Design and Selection

Guillem Casadevall

Jordi Casadevall

Cristina Duran

Sílvia Osuna

2024

Computational Enzyme Design

Gert Kiss

Nihan Çelebi‐Ölçüm

Rocco Moretti

David Baker

KN Houk

2013/5/27

Controlling Monoterpene Isomerization by Guiding Challenging Carbocation Rearrangement Reactions in Engineered Squalene‐Hopene Cyclases

Angewandte Chemie International Edition

Julian Ludwig

Christian Curado‐Carballada

Stephan C Hammer

Andreas Schneider

Svenja Diether

...

2024/3/18

Engineering of conserved sequence motif 1 residues in halohydrin dehalogenase HheC simultaneously enhances activity, stability and enantioselectivity

Sophie Staar

Miquel Estévez-Gay

Felix Kaspar

Sílvia Osuna

Anett Schallmey

2024/3/13

Origin Of Evolutionary Bifurcation In An Enzyme

bioRxiv

Charlotte M Miton

Eleanor C Campbell

Joe A Kaczmarski

Ferran Feixas

Adrian Romero-Rivera

...

2023

AlphaFold2 and Deep Learning for Elucidating Enzyme Conformational Flexibility and Its Application for Design

Journal of the American Chemical Society (JACS), 2023, vol. 3, núm. 6, p. 1554-1562

Guillem Casadevall Frano

Cristina Duran i Rebenaque

Sílvia Osuna Oliveras

2023/6/6

Computational design of industrially relevant enzymes

Sílvia Osuna

2023/10/18

Brave new surfactant world revisited by thermoalkalophilic lipases: computational insights into the role of SDS as a substrate analog

Physical Chemistry Chemical Physics

Mohamed Shehata

Aişe Ünlü

Javier Iglesias-Fernández

Sílvia Osuna

O Ugur Sezerman

...

2023

Titelbild: Verwendung der Struktur und Dynamik der Squalen‐Hopen‐Zyklase für die (−)‐Ambroxid Produktion (Angew. Chem. 22/2023)

Angewandte Chemie

Andreas Schneider

Christian Curado

Thomas B Lystbaek

Sílvia Osuna

Bernhard Hauer

2023/5/22

Designing Efficient Enzymes: Eight Predicted Mutations Convert a Hydroxynitrile Lyase into an Efficient Esterase

bioRxiv

Guillem Casadevall

Colin Pierce

Bo Guan

Javier Iglesias-Fernandez

Huey-Yee Lim

...

2023/8/24

Verwendung der Struktur und Dynamik der Squalen‐Hopen‐Zyklase für die (−)‐Ambroxid Produktion

Angewandte Chemie

Andreas Schneider

Christian Curado

Thomas B Lystbaek

Sílvia Osuna

Bernhard Hauer

2023/5/22

A new family of soluble epoxide hydrolase inhibitors: in vivo evaluation in a murine model of chemotherapy-induced neuropathic pain

Santiago Vázquez

Sandra Codony

Beatrice Jora

Andreea L Turcu

Carla Calvó-Tusell

...

2023/7/18

Harnessing the Structure and Dynamics of the Squalene‐Hopene Cyclase for (−)‐Ambroxide Production

Angewandte Chemie International Edition

Andreas Schneider

Christian Curado

Thomas B Lystbaek

Sílvia Osuna

Bernhard Hauer

2023/5/22

Decrypting the languages of allostery in membrane-bound K-Ras4B using four complementary in silico approaches

bioRxiv

Matteo Castelli

Filippo Marchetti

Sílvia Osuna

A Sofia F. Oliveira

Adrian J Mulholland

...

2023/7/14

Decrypting Allostery in Membrane-Bound K-Ras4B Using Complementary In Silico Approaches Based on Unbiased Molecular Dynamics Simulations

Journal of the American Chemical Society

Matteo Castelli

Filippo Marchetti

Sílvia Osuna

A Sofia F. Oliveira

Adrian J Mulholland

...

2023/12/20

In vivo evaluation of soluble epoxide hydrolase inhibitors in murine models of allodynia, chemotherapy-induced neuropathic pain and visceral pain

Santiago Vázquez

Sandra Codony

Beatrice Jora

José M Entrena

M Santos-Caballero

...

2023/3/7

C–H Bonds as Functional Groups: Simultaneous Generation of Multiple Stereocenters by Enantioselective Hydroxylation at Unactivated Tertiary C–H Bonds

Journal of the American Chemical Society

Andrea Palone

Guillem Casadevall

Sergi Ruiz-Barragan

Arnau Call

Sílvia Osuna

...

2023/7/11

Retracing the Rapid Evolution of an Herbicide-Degrading Enzyme by Protein Engineering

ACS Catalysis

Markus R Busch

Lukas Drexler

Dhani Ram Mahato

Caroline Hiefinger

Sílvia Osuna

...

2023/11/17

See List of Professors in Silvia Osuna University(Universidad de Gerona)

Co-Authors

H-index: 162
Kendall N. Houk

Kendall N. Houk

University of California, Los Angeles

H-index: 95
NAZARIO MARTIN LEON - ORCID: 0000-0002-5355-1477

NAZARIO MARTIN LEON - ORCID: 0000-0002-5355-1477

Universidad Complutense de Madrid

H-index: 79
Miquel Solà Puig (ORCID: 0000-0002-1917-7450)

Miquel Solà Puig (ORCID: 0000-0002-1917-7450)

Universidad de Gerona

H-index: 48
Josep M. Luis

Josep M. Luis

Universidad de Gerona

H-index: 33
Marc Garcia-Borràs

Marc Garcia-Borràs

University of California, Los Angeles

H-index: 30
Ferran Feixas

Ferran Feixas

Universidad de Gerona

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