Seio Kohji

About Seio Kohji

Seio Kohji, With an exceptional h-index of 27 and a recent h-index of 11 (since 2020), a distinguished researcher at Tokyo Institute of Technology, specializes in the field of Nucleic acid chemistry, Nucleic acid therapeutics.

His recent articles reflect a diverse array of research interests and contributions to the field:

Synthesis and Conformational Analyses of Cyclonucleoside Having 13-Membered Ring Bridging Nucleobase and 5′-Position via a Linker Containing Sulfonamide

Alteration of target cleavage patterns and off-target reduction of antisense oligonucleotides incorporating 2-N-carbamoyl-or (2-pyridyl) guanine

Synthesis of 2′-O-[3-(N-methylsulfamoyl) propan-1-yl] ribothymidine as a potentially applicable 2′-modified nucleoside for antisense oligonucleotides

Method for reducing toxicity of antisense nucleic acids

Quantification of synthetic errors during chemical synthesis of DNA and its suppression by non-canonical nucleosides

Artificial nucleoside and artificial nucleotide, and artificial oligonucleotide

Selective and stable base pairing by alkynylated nucleosides featuring a spatially-separated recognition interface

Oligodeoxynucleotides Modified with 2′-O-(Cysteinylaminobutyl)carbamoylethylribothymidine Residues for Native Chemical Ligation with Peptide at Internal …

Seio Kohji Information

University

Position

___

Citations(all)

2699

Citations(since 2020)

673

Cited By

2268

hIndex(all)

27

hIndex(since 2020)

11

i10Index(all)

95

i10Index(since 2020)

14

Email

University Profile Page

Google Scholar

Seio Kohji Skills & Research Interests

Nucleic acid chemistry

Nucleic acid therapeutics

Top articles of Seio Kohji

Synthesis and Conformational Analyses of Cyclonucleoside Having 13-Membered Ring Bridging Nucleobase and 5′-Position via a Linker Containing Sulfonamide

Organic Letters

2023/10/19

Alteration of target cleavage patterns and off-target reduction of antisense oligonucleotides incorporating 2-N-carbamoyl-or (2-pyridyl) guanine

Organic & Biomolecular Chemistry

2023

Synthesis of 2′-O-[3-(N-methylsulfamoyl) propan-1-yl] ribothymidine as a potentially applicable 2′-modified nucleoside for antisense oligonucleotides

Bioorganic & Medicinal Chemistry

2022/11/1

Method for reducing toxicity of antisense nucleic acids

2022/10/5

Quantification of synthetic errors during chemical synthesis of DNA and its suppression by non-canonical nucleosides

Scientific Reports

2022/7/15

Artificial nucleoside and artificial nucleotide, and artificial oligonucleotide

2022/7/12

Selective and stable base pairing by alkynylated nucleosides featuring a spatially-separated recognition interface

Nucleic Acids Research

2022/4/8

Oligodeoxynucleotides Modified with 2′-O-(Cysteinylaminobutyl)carbamoylethylribothymidine Residues for Native Chemical Ligation with Peptide at Internal …

Bioconjugate Chemistry

2022/2/7

Insertion of a methylene group into the backbone of an antisense oligonucleotide reveals the importance of deoxyribose recognition by RNase H

Organic & Biomolecular Chemistry

2022

Production method and production intermediate for guanosine-3', 5'-bisdiphosphate

2021/4/1

Synthesis of 2′-O-alkylcarbamoylethyl-modified oligonucleotides with enhanced nuclease resistance that form isostable duplexes with complementary RNA

Bioorganic & Medicinal Chemistry Letters

2021/3/1

Antisense oligonucleotide reduced in toxicity

2021/2/25

Novel EGFP reporter cell and mouse models for sensitive imaging and quantification of exon skipping

Scientific Reports

2020/6/22

Transcription of DNA duplex containing deoxypseudouridine and deoxypseudoisocytidine, and inhibition of transcription by triplex forming oligonucleotide that recognizes the …

Nucleosides, Nucleotides & Nucleic Acids

2020/6/2

Synthesis of Deoxypseudouridine 5′-Triphosphate Bearing the Photoremovable Protecting Group at the N1 Position Capable of Enzymatic Incorporation to DNA

The Journal of Organic Chemistry

2020/1/7

See List of Professors in Seio Kohji University(Tokyo Institute of Technology)