Sean Simmons

Lupus autoantibodies initiate neuroinflammation sustained by continuous HMGB1: RAGE signaling and reversed by increased LAIR-1 expression

Neuronal-class specific molecular cues drive differential myelination in the neocortex

Lupus autoantibodies initiate a maladaptive equilibrium sustained by HMGB1: RAGE signaling and reversed by LAIR-1: C1q signaling

Heterochronic parabiosis reprograms the mouse brain transcriptome by shifting aging signatures in multiple cell types

Mostly natural sequencing-by-synthesis for scRNA-seq using Ultima sequencing

Brain-region-specific changes in neurons and glia and dysregulation of dopamine signaling in Grin2a mutant mice

Massively parallel in vivo Perturb-seq reveals cell type-specific transcriptional networks in cortical development

A single-cell map of antisense oligonucleotide activity in the brain