Sean Lawler PhD

Sean Lawler PhD

Harvard University

H-index: 54

North America-United States

About Sean Lawler PhD

Sean Lawler PhD, With an exceptional h-index of 54 and a recent h-index of 40 (since 2020), a distinguished researcher at Harvard University, specializes in the field of Identifying effective brain tumor therapies.

His recent articles reflect a diverse array of research interests and contributions to the field:

Brain derived endothelial cells as a mediator of cGAS-STING driven anti-tumor efficacy in glioblastoma

Exploring the effects of Indirubins in pediatric diffuse high grade glioma models

Identification of transcriptomic signatures associated with glioblastoma recurrence

Abstract A011: Stopping brain tumors in their tracks: the role of RhoGTPase activating proteins (ARHGAPs) in glioma cell migration and invasion

Assessment of the response to STING agonist treatment and potentiation by manganese in glioblastoma cells and the tumor microenvironment

MODL-36. EX VIVO GSC CULTURES RETAIN PATIENT-UNIQUE HALLMARK GENE EXPRESSIONS AND PREDICT PATIENT RESPONSE TO TMZ MORE SPECIFICALLY THAN MGMT PROMOTER STATUS

Nucleolin promotes angiogenesis and endothelial metabolism along the oncofetal axis in the human brain vasculature

Ex vivo drug sensitivity screening predicts response to temozolomide in glioblastoma patients and identifies candidate biomarkers

Sean Lawler PhD Information

University

Position

Department of Neurosurgery, Brigham and Women's Hospital

Citations(all)

14399

Citations(since 2020)

6440

Cited By

10696

hIndex(all)

54

hIndex(since 2020)

40

i10Index(all)

111

i10Index(since 2020)

89

Email

University Profile Page

Google Scholar

Sean Lawler PhD Skills & Research Interests

Identifying effective brain tumor therapies

Top articles of Sean Lawler PhD

Title

Journal

Author(s)

Publication Date

Brain derived endothelial cells as a mediator of cGAS-STING driven anti-tumor efficacy in glioblastoma

Cancer Research

Andrea Schmidt

Sandra Remson

Philippa Vaughn-Beaucaire

Jorge L Jimenez-Macias

Praveen Srinivasan

...

2024/3/22

Exploring the effects of Indirubins in pediatric diffuse high grade glioma models

Cancer Research

Jasmine S Clark

Jorge Jimenez-Macias

Philippa Vaughn-Beaucaire

Shengliang Zhang

Wafik El-Deiry

...

2024/3/22

Identification of transcriptomic signatures associated with glioblastoma recurrence

Sean Lawler

2024/3/12

Abstract A011: Stopping brain tumors in their tracks: the role of RhoGTPase activating proteins (ARHGAPs) in glioma cell migration and invasion

Cancer Research

Philippa C Vaughn-Beaucaire

Sean Lawler

Anke Bruning-Richardson

William Hawkins

Jorge Jimenez-Macias

...

2024/3/4

Assessment of the response to STING agonist treatment and potentiation by manganese in glioblastoma cells and the tumor microenvironment

Cancer Research

Andrea Schmidt

Caroline Sweeney

William M Hawkins

Jorge L Jimenez-Macias

Sean Lawler

2023/4/4

MODL-36. EX VIVO GSC CULTURES RETAIN PATIENT-UNIQUE HALLMARK GENE EXPRESSIONS AND PREDICT PATIENT RESPONSE TO TMZ MORE SPECIFICALLY THAN MGMT PROMOTER STATUS

Neuro-Oncology

Ioannis Ntafoulis

Anne Kleijn

Jie Ju

Kevin Jimenez-Cowell

Federica Fabro

...

2023/11/1

Nucleolin promotes angiogenesis and endothelial metabolism along the oncofetal axis in the human brain vasculature

JCI insight

Marc Schwab

Ignazio de Trizio

Moheb Ghobrial

Jau-Ye Shiu

Oguzkan Sürücü

...

2023/4/4

Ex vivo drug sensitivity screening predicts response to temozolomide in glioblastoma patients and identifies candidate biomarkers

British Journal of Cancer

Ioannis Ntafoulis

Anne Kleijn

Jie Ju

Kevin Jimenez-Cowell

Federica Fabro

...

2023/10/12

Digging deeper for new targets in bevacizumab resistance

Sean E Lawler

2023/2/1

DIPG-41. EXPLORING BRAIN PENETRANT PEPTIDE-DRUG CONJUGATES IN DIFFUSE INTRINSIC PONTINE GLIOMA MODELS

Neuro-Oncology

Jasmine Clark

Samuel McKinnon

Jorge_Luis JImenez-Macias

Edward Miller

Andrei Loas

...

2023/6

CMV infection in glioblastoma-Oncomodulation through changes to the glioma immune landscape

Brain and Spine

Harald Krenzlin

Leon Scmidt

Felix Corr

Philipp Einhäuser

Alice Dauth

...

2023/1/1

PPRX-1701, a nanoparticle formulation of 6′-bromoindirubin acetoxime, improves delivery and shows efficacy in preclinical GBM models

Cell Reports Medicine

Mykola Zdioruk

Jorge-Luis Jimenez-Macias

Michal Oskar Nowicki

Katherine E Manz

Kurt D Pennell

...

2023/5/16

Role of senescent tumor cells in building a cytokine shield in the tumor microenvironment: mathematical modeling

Journal of Mathematical Biology

Yangjin Kim

Junho Lee

Chaeyoung Lee

Sean Lawler

2023/1

Uncovering transcriptomic landscape alterations of CAN-2409 in in vitro and in vivo glioma models

Frontiers in Medicine

Marilin S Koch

Mykola Zdioruk

Michal O Nowicki

Michael S Hoetker

Zachary T Herbert

...

2023/5/9

DDEL-04. MODULATION OF THE BLOOD-TUMOR BARRIER FOR IMPROVED DRUG DELIVERY IN GLIOBLASTOMA

Neuro-Oncology

Jorge-Luis Jimenez-Macias

Zheyun Xu

Doug Anthony

Alex Brodsky

George Tollefson

...

2023/11/1

Mechanisms of cytomegalovirus to tumor transmission across the blood brain barrier in glioblastoma

Brain and Spine

H Krenzlin

L Schmidt

N Lemmermann

S Lawler

F Ringel

...

2022/1/1

Pt (IV)-M13, a blood-brain-barrier penetrant macrocyclic peptide-platinum (IV) conjugate, leads to enhanced drug uptake and efficacy in murine glioblastoma models

Cancer Research

Jorge-Luis Jimenez-Macias

Yen-Chun Lee

Tomer Finkelberg

Gilles Berger

Michal Nowicki

...

2022/6/15

Combination gmci and atri cancer treatment

2022/7/14

A Pt (IV)-conjugated brain penetrant macrocyclic peptide shows pre-clinical efficacy in glioblastoma

Journal of Controlled Release

JL Jimenez-Macias

Y-C Lee

E Miller

T Finkelberg

M Zdioruk

...

2022/12/1

Inflammasome activation: from molecular mechanisms to autoinflammation

Samuel Lara‐Reyna

Emily A Caseley

Joanne Topping

François Rodrigues

Jorge Jimenez Macias

...

2022

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