Scott Guimond
Keele University
H-index: 34
Europe-United Kingdom
Top articles of Scott Guimond
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
A sulphated glycosaminoglycan extract from Placopecten magellanicus inhibits the Alzheimer's disease β-site amyloid precursor protein cleaving enzyme 1 (BACE-1) | Carbohydrate Research | Courtney J Mycroft-West Anthony J Devlin Lynsay C Cooper Scott E Guimond Patricia Procter | 2023/3/1 |
High sensitivity (zeptomole) detection of BODIPY-labelled heparan sulfate (HS) disaccharides by ion-paired RP-HPLC and LIF detection enables analysis of HS from mosquito midguts | Analytical Methods | Marissa L Maciej-Hulme Anaëlle CN Leprince Andre Lavin Scott E Guimond Jeremy E Turnbull | 2023 |
Synthetic heparan sulfate mimetic pixatimod (PG545) potently inhibits SARS-CoV-2 by disrupting the spike–ACE2 interaction | ACS central science | Scott E Guimond Courtney J Mycroft-West Neha S Gandhi Julia A Tree Thuy T Le | 2022/3/29 |
The hyperlipidaemic drug fenofibrate significantly reduces infection by SARS-CoV-2 in cell culture models | Frontiers in Pharmacology | Scott P Davies Courtney J Mycroft-West Isabel Pagani Harriet J Hill Yen-Hsi Chen | 2021/8/6 |
Glycosaminoglycans from Litopenaeus vannamei Inhibit the Alzheimer’s Disease β Secretase, BACE1 | Marine drugs | Courtney J Mycroft-West Anthony J Devlin Lynsay C Cooper Scott E Guimond Patricia Procter | 2021/4/3 |
Pixatimod (PG545), a clinical-stage heparan sulfate mimetic, is a potent inhibitor of the SARS-CoV-2 virus (preprint) | Scott E Guimond Courtney J Mycroft-West Neha S Gandhi Julia A Tree Karen R Buttigieg | 2020 | |
Inhibition of BACE1, the β-secretase implicated in Alzheimer’s disease, by a chondroitin sulfate extract from Sardina pilchardus | Neural regeneration research | Courtney J Mycroft-West Anthony J Devlin Lynsay C Cooper Patricia Procter Gavin J Miller | 2020/8/1 |
SARS-Cov-2 spike S1 receptor binding domain undergoes conformational change upon interaction with low molecular weight heparins | BioRxiv | Courtney J Mycroft-West Dunhao Su Yong Li Scott E Guimond Timothy R Rudd | 2020/4/29 |
Glycosaminoglycans induce conformational change in the SARS-CoV-2 spike S1 receptor binding domain | BioRxiv | Courtney J Mycroft-West Dunhao Su Yong Li Scott E Guimond Timothy R Rudd | 2020/4/29 |
Heparin inhibits cellular invasion by SARS-CoV-2: structural dependence of the interaction of the spike S1 receptor-binding domain with heparin | Thrombosis and haemostasis | Courtney J Mycroft-West Dunhao Su Isabel Pagani Timothy R Rudd Stefano Elli | 2020/12 |
Shotgun ion mobility mass spectrometry sequencing of heparan sulfate saccharides | Nature communications | Rebecca L Miller Scott E Guimond Ralf Schwörer Olga V Zubkova Peter C Tyler | 2020/3/20 |
Chemical synthesis of a sulfated D-glucosamine library and evaluation of cell proliferation capabilities | Carbohydrate Research | Aisling Ni Cheallaigh Scott E Guimond Stefan Oscarson Gavin J Miller | 2020/9/1 |
The 2019 coronavirus (SARS-CoV-2) surface protein (Spike) S1 Receptor Binding Domain undergoes conformational change upon heparin binding | BioRxiv | Courtney Mycroft-West Dunhao Su Stefano Elli Yong Li Scott Guimond | 2020/3/2 |
沙丁鱼硫酸软骨素提取物可抑制阿尔茨海默病有关淀粉样前体蛋白 β 位点裂解酶 1 | 中国神经再生研究 (英文版) | Courtney J Mycroft-West Anthony J Devlin Lynsay C Cooper Patricia Procter Gavin J Miller | 2020/8/15 |
