Samuel Lai
University of North Carolina at Chapel Hill
H-index: 50
North America-United States
Top articles of Samuel Lai
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
Siglec15/TGF‐β bispecific antibody mediates synergistic anti‐tumor response against 4T1 triple negative breast cancer in mice | Bioengineering & Translational Medicine | Limei Shen Alison M Schaefer Karthik Tiruthani Whitney Wolf Samuel K Lai | 2024 |
Free PEG Suppresses Anaphylaxis to PEGylated Nanomedicine in Swine | ACS nano | Limei Shen Zhongbo Li Alice Ma Carlos Cruz-Teran Anne Talkington | 2024/3/12 |
Engineering a “muco‐trapping” ACE2‐immunoglobulin hybrid with picomolar affinity as an inhaled, pan‐variant immunotherapy for COVID‐19 | Bioengineering & Translational Medicine | Karthik Tiruthani Carlos Cruz‐Teran Jasper FW Chan Alice Ma Morgan McSweeney | 2024/2 |
Development of anti-PEG IgG/IgM/IgE ELISA assays for profiling anti-PEG immunoglobulin response in PEG-sensitized individuals and patients with alpha-gal allergy | Journal of Controlled Release | Zhongbo Li Alice Ma Ian Miller Rachel Starnes Anne Talkington | 2024/2/1 |
Inhaled “Muco‐Trapping” Monoclonal Antibody Effectively Treats Established Respiratory Syncytial Virus (RSV) Infections | Advanced Science | Morgan D McSweeney Sarhad Alnajjar Alison M Schaefer Zach Richardson Whitney Wolf | 2024/1/15 |
Broadly neutralizing antibodies consistently trap HIV-1 in fresh cervicovaginal mucus from select individuals | Acta Biomaterialia | Alison Schaefer Bing Yang Holly A Schroeder Dimple Harit Mike S Humphry | 2023/10/1 |
Pegloticase co-administered with high MW polyethylene glycol effectively reduces PEG-immunogenicity and restores prolonged circulation in mouse | Acta Biomaterialia | Zhongbo Li Limei Shen Alice Ma Anne Talkington Zibo Li | 2023/10/15 |
Modeling identifies variability in SARS-CoV-2 uptake and eclipse phase by infected cells as principal drivers of extreme variability in nasal viral load in the 48 h post infection | Journal of Theoretical biology | Jason Pearson Timothy Wessler Alex Chen Richard C Boucher Ronit Freeman | 2023/5/21 |
Cervicovaginal mucus barrier properties during pregnancy are impacted by the vaginal microbiome | Frontiers in Cellular and Infection Microbiology | Hannah C Zierden Kevin DeLong Fareeha Zulfiqar Jairo Ortiz Ortiz Victoria Laney | 2023/3/31 |
Stable nebulization and muco‐trapping properties of regdanvimab/IN‐006 support its development as a potent, dose‐saving inhaled therapy for COVID‐19 | Bioengineering & translational medicine | Morgan D McSweeney Ian Stewart Zach Richardson Hyunah Kang Yoona Park | 2023/1 |
Challenges and opportunities in gene editing of B Cells | Jasmine Edelstein Marshall Fritz Samuel K Lai | 2022/10/12 | |
Modeling insights into SARS-CoV-2 respiratory tract infections prior to immune protection | Biophysical Journal | Alexander Chen Timothy Wessler Katherine Daftari Kameryn Hinton Richard C Boucher | 2022/5/3 |
The biophysical principles underpinning muco-trapping functions of antibodies | Alison Schaefer Samuel K Lai | 2022/4/29 | |
Nano-trapping CXCL13 reduces regulatory B cells in tumor microenvironment and inhibits tumor growth | Journal of Controlled Release | Limei Shen Jingjing Li Qi Liu Manisit Das Wantong Song | 2022/3/1 |
A PBPK model recapitulates early kinetics of anti-PEG antibody-mediated clearance of PEG-liposomes | Journal of Controlled Release | Anne M Talkington Morgan D McSweeney Timothy Wessler Marielle K Rath Zibo Li | 2022/3/1 |
Pre-treatment with high molecular weight free PEG effectively suppresses anti-PEG antibody induction by PEG-liposomes in mice | Journal of controlled release | Morgan D McSweeney Limei Shen Alexander C DeWalle Jordan B Joiner Elizabeth C Ciociola | 2021/1/10 |
Hexavalent sperm-binding IgG antibody released from vaginal film for development of potent on-demand nonhormonal female contraception | Proceedings of the National Academy of Sciences | Bhawana Shrestha Kathleen Vincent Alison Schaefer Yong Zhu Gracie Vargas | 2021/11/30 |
Anaphylaxis to Pfizer/BioNTech mRNA COVID-19 vaccine in a patient with clinically confirmed PEG allergy | Frontiers in Allergy | Morgan D McSweeney Manoj Mohan Scott P Commins Samuel K Lai | 2021/9/29 |
High MW polyethylene glycol prolongs circulation of pegloticase in mice with anti-PEG antibodies | Journal of Controlled Release | Anne M Talkington Morgan D McSweeney Tao Zhang Zibo Li Andrew C Nyborg | 2021/10/10 |
Bispecific binder redirected lentiviral vector enables in vivo engineering of CAR-T cells | Journal for immunotherapy of cancer | Justin T Huckaby Elisa Landoni Timothy M Jacobs Barbara Savoldo Gianpietro Dotti | 2021 |
