Sakthivel Sadayappan

Sakthivel Sadayappan

University of Cincinnati

H-index: 48

North America-United States

About Sakthivel Sadayappan

Sakthivel Sadayappan, With an exceptional h-index of 48 and a recent h-index of 33 (since 2020), a distinguished researcher at University of Cincinnati, specializes in the field of Cardiac myosin binding protein-C, MYBPC1, MYBPC2, MYBPC3.

His recent articles reflect a diverse array of research interests and contributions to the field:

BRD9-SMAD2/3 orchestrates stemness and tumorigenesis in pancreatic ductal adenocarcinoma

The structural OFF and ON states of myosin can be decoupled from the biochemical super-and disordered-relaxed states

Dynamic changes in mitral valve extracellular matrix, tissue mechanics and function in a mouse model of Marfan syndrome

frontiers ORIGINAL RESEARCH in Cardiovascular Medicine published: 23 December 2021 doi: 10.3389/fcvm. 2021.766339

Macrophage-enriched Sectm1a promotes efficient efferocytosis to attenuate ischemia/reperfusion-induced cardiac injury

Hypertrophic cardiomyopathy in MYBPC3 carriers in aging

Dissecting the mechanisms by which a pathogenic variant in cardiac TnT tail domain leads to disturbed myofilament performance

Cardiac troponin T N-domain variant destabilizes the actin interface resulting in disturbed myofilament function

Sakthivel Sadayappan Information

University

Position

Professor of Internal Medicine at

Citations(all)

7191

Citations(since 2020)

4053

Cited By

4693

hIndex(all)

48

hIndex(since 2020)

33

i10Index(all)

112

i10Index(since 2020)

96

Email

University Profile Page

University of Cincinnati

Google Scholar

View Google Scholar Profile

Sakthivel Sadayappan Skills & Research Interests

Cardiac myosin binding protein-C

MYBPC1

MYBPC2

MYBPC3

Top articles of Sakthivel Sadayappan

Title

Journal

Author(s)

Publication Date

BRD9-SMAD2/3 orchestrates stemness and tumorigenesis in pancreatic ductal adenocarcinoma

Gastroenterology

Yuliang Feng

Liuyang Cai

Martin Pook

Feng Liu

Chao-Hui Chang

...

2024/1/1

The structural OFF and ON states of myosin can be decoupled from the biochemical super-and disordered-relaxed states

PNAS nexus

Vivek P Jani

Taejeong Song

Chengqian Gao

Henry Gong

Sakthivel Sadayappan

...

2024/2

Dynamic changes in mitral valve extracellular matrix, tissue mechanics and function in a mouse model of Marfan syndrome

Matrix Biology

Brittany A Gonzalez

Samuel W Harmeyer

Taejeong Song

Sakthivel Sadayappan

Katherine E Yutzey

2024/2/1

frontiers ORIGINAL RESEARCH in Cardiovascular Medicine published: 23 December 2021 doi: 10.3389/fcvm. 2021.766339

Developments in Cardiac Implantable Electronic Device Therapy: How can we improve clinical implementation?

Mate Vamos

AZ Sint-Jan Brugge-Oostende

Toshiaki Sato

Rong Bai

Xiaohan Fan

...

2023/6/27

Macrophage-enriched Sectm1a promotes efficient efferocytosis to attenuate ischemia/reperfusion-induced cardiac injury

JCI insight

Xiaohong Wang

Wa Du

Yutian Li

Hui-Hui Yang

Yu Zhang

...

2024/3/3

Hypertrophic cardiomyopathy in MYBPC3 carriers in aging

The Journal of Cardiovascular Aging

Kalyani Ananthamohan

Julian E Stelzer

Sakthivel Sadayappan

2024/1/11

Dissecting the mechanisms by which a pathogenic variant in cardiac TnT tail domain leads to disturbed myofilament performance

Biophysical Journal

Maicon Landim-Vieira

Weikang Ma

Taejeong Song

Hosna Rastegarpouyani

Coen A Ottenheijm

...

2023/2/10

Cardiac troponin T N-domain variant destabilizes the actin interface resulting in disturbed myofilament function

Proceedings of the National Academy of Sciences

Maicon Landim-Vieira

Weikang Ma

Taejeong Song

Hosna Rastegarpouyani

Henry Gong

...

2023/6/6

Machine learning-based classification of cardiac relaxation impairment using sarcomere length and intracellular calcium transients

Computers in biology and medicine

Rana Raza Mehdi

Mohit Kumar

Emilio A Mendiola

Sakthivel Sadayappan

Reza Avazmohammadi

2023/9/1

Myofilament alterations associated with human R14del-phospholamban cardiomyopathy

International Journal of Molecular Sciences

Mohit Kumar

Kobra Haghighi

Sheryl Koch

Jack Rubinstein

Francesca Stillitano

...

2023/1/31

Mutation Spectrum of β-Thalassemia in Some Ethnic Groups of North Maharashtra, India

Hemoglobin

Ranjeet Kumar

Syed Abrar Ahmad

Mustafa Ozdemir

Sakthivel Sadayappan

Varsha Wankhade

2023/5/4

Abstract P2008. 1: Association Of Myocardial Stiffening With Impaired Relaxation In A Diabetic Murine Model Of Left Ventricular Diastolic Dysfunction

Circulation Research

Tanmay Mukherjee

Sunder Neelakantan

Elizabeth Fugate

Emilio Mendiola

Aaron Burton

...

2023/8/4

IL-1β-mediated adaptive reprogramming of endogenous human cardiac fibroblasts to cells with immune features during fibrotic remodeling

Communications biology

Jamila H Siamwala

Francesco S Pagano

Patrycja M Dubielecka

Malina J Ivey

Jose Pedro Guirao-Abad

...

2023/11/25

Myosin-binding protein C stabilizes, but is not the sole determinant of SRX myosin in cardiac muscle

Journal of General Physiology

Shane Nelson

Samantha Beck-Previs

Sakthivel Sadayappan

Carl Tong

David M Warshaw

2023/1/23

Abstract P3038: Novel MicroRNAs Targeting Myosin Binding Protein-C3 Gene In Hypertrophic Cardiomyopathy

Circulation Research

Kalyani Ananthamohan

Akhil Baby

Anil Jegga

Sakthivel Sadayappan

2023/8/4

Multiscale characterization of left ventricle active behavior in the mouse

Acta biomaterialia

Sunder Neelakantan

Mohit Kumar

Emilio A Mendiola

Haley Phelan

Vahid Serpooshan

...

2023/5/1

Unlocking the Role of sMyBP-C: A Key Player in Skeletal Muscle Development and Growth

bioRxiv

Taejeong Song

James W McNamara

Akhil Baby

Weikang Ma

Maicon Landim-Vieira

...

2023/10/25

Structural and Phenotypic Correction of K210del Genetic Cardiomyopathy by an FDA Approved Drug

Hesham Sadek

Ping Wang

Mahmoud Ahmed

Ngoc Uyen Nhi Nguyen

Ivan Menendez-Montes

...

2023/1/12

Etiology of genetic muscle disorders induced by mutations in fast and slow skeletal MyBP-C paralogs

Taejeong Song

Maicon Landim-Vieira

Mustafa Ozdemir

Caroline Gott

Onur Kanisicak

...

2023/3

Lipocalin 10 is essential for protection against inflammation-triggered vascular leakage by activating LDL receptor-related protein 2-slingshot homologue 1 signalling pathway

Cardiovascular Research

Hongyan Zhao

Peng Wang

Xiaohong Wang

Wa Du

Hui-Hui Yang

...

2023/8

See List of Professors in Sakthivel Sadayappan University(University of Cincinnati)

Co-Authors

H-index: 150
David A. Kass

David A. Kass

Johns Hopkins University

H-index: 96
EVANGELIA KRANIAS

EVANGELIA KRANIAS

University of Cincinnati

H-index: 47
Sharlene Day

Sharlene Day

University of Pennsylvania

H-index: 42
Mayandi Sivaguru

Mayandi Sivaguru

University of Illinois at Urbana-Champaign

H-index: 15
kyounghwan lee

kyounghwan lee

University of Massachusetts Medical School

H-index: 13
MOHIT KUMAR

MOHIT KUMAR

University of Cincinnati

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