S P Lees-Miller, PhD, FRSC

S P Lees-Miller, PhD, FRSC

University of Calgary

H-index: 88

North America-Canada

About S P Lees-Miller, PhD, FRSC

S P Lees-Miller, PhD, FRSC, With an exceptional h-index of 88 and a recent h-index of 43 (since 2020), a distinguished researcher at University of Calgary, specializes in the field of DNA-PK, NHEJ, DNA double strand break repair.

His recent articles reflect a diverse array of research interests and contributions to the field:

Automating data analysis for hydrogen/deuterium exchange mass spectrometry using data-independent acquisition methodology

Prevalence and Prognostic Significance of PIK3CA Mutation and CNV Status and Phosphorylated AKT Expression in Patients With Cervical Cancer Treated With Primary Surgery

Author Correction: Automating data analysis for hydrogen/deuterium exchange mass spectrometry using data-independent acquisition methodology

High-Efficiency Enrichment by Saturating Nanoliters of Protein Affinity Media

Cryo-EM visualization of DNA-PKcs structural intermediates in NHEJ

Cryo-EM visualization of state transition during non-homologous end-joining (NHEJ)

How to fix DNA breaks: new insights into the mechanism of non-homologous end joining

Purification of DNA-dependent protein kinase catalytic subunit (DNA-PKcs) from HeLa cells

S P Lees-Miller, PhD, FRSC Information

University

Position

___

Citations(all)

25207

Citations(since 2020)

5464

Cited By

21705

hIndex(all)

88

hIndex(since 2020)

43

i10Index(all)

160

i10Index(since 2020)

125

Email

University Profile Page

University of Calgary

Google Scholar

View Google Scholar Profile

S P Lees-Miller, PhD, FRSC Skills & Research Interests

DNA-PK

NHEJ

DNA double strand break repair

Top articles of S P Lees-Miller, PhD, FRSC

Title

Journal

Author(s)

Publication Date

Automating data analysis for hydrogen/deuterium exchange mass spectrometry using data-independent acquisition methodology

Nature communications

Frantisek Filandr

Vladimir Sarpe

Shaunak Raval

D Alex Crowder

Morgan F Khan

...

2024/3/11

Prevalence and Prognostic Significance of PIK3CA Mutation and CNV Status and Phosphorylated AKT Expression in Patients With Cervical Cancer Treated With Primary Surgery

International Journal of Gynecological Pathology

Kevin Martell

John B McIntyre

Tasnima Abedin

Elizabeth N Kornaga

Angela MY Chan

...

2024/3/1

Author Correction: Automating data analysis for hydrogen/deuterium exchange mass spectrometry using data-independent acquisition methodology

nature communications

Frantisek Filandr

Vladimir Sarpe

Shaunak Raval

D Alex Crowder

Morgan F Khan

...

2024

High-Efficiency Enrichment by Saturating Nanoliters of Protein Affinity Media

Analytical Chemistry

Shaunak Raval

Pauline Douglas

Danny Laurent

Morgan F Khan

Susan P Lees-Miller

...

2023/10/18

Cryo-EM visualization of DNA-PKcs structural intermediates in NHEJ

Science advances

Siyu Chen

Alex Vogt

Linda Lee

Tasmin Naila

Ryan McKeown

...

2023/5/31

Cryo-EM visualization of state transition during non-homologous end-joining (NHEJ)

Biophysical Journal

Siyu Chen

Linda Lee

Tasmin Naila

Ryan McKeown

Susan Fishbain

...

2023/2/10

How to fix DNA breaks: new insights into the mechanism of non-homologous end joining

Alex Vogt

Yuan He

Susan P Lees-Miller

2023/10/31

Purification of DNA-dependent protein kinase catalytic subunit (DNA-PKcs) from HeLa cells

Linda Lee

Yaping Yu

Susan P Lees-Miller

2022/3/16

A genetic roadmap to the response to genotoxic agents in human cells

Faculty Reviews

Alberto Ciccia

Roger A Greenberg

Susan P Lees-Miller

Andre Nussenzweig

2022

KRCC1, a modulator of the DNA damage response

Nucleic Acids Research

Fiifi Neizer-Ashun

Shailendra Kumar Dhar Dwivedi

Anindya Dey

Elangovan Thavathiru

William L Berry

...

2022/10/28

KRCC1, a novel modulator of the DNA damage response

Fiifi Neizer-Ashun

Shailendra Dwivedi

Anindya Dey

Elangovan Thavathiru

William Berry

...

2022/4/8

Uncovering DNA-PKcs ancient phylogeny, unique sequence motifs and insights for human disease

James P Lees-Miller

Alexander Cobban

Panagiotis Katsonis

Albino Bacolla

Susan E Tsutakawa

...

2021/8/1

Visualizing functional dynamicity in the DNA-dependent protein kinase holoenzyme DNA-PK complex by integrating SAXS with cryo-EM

Michal Hammel

Daniel J Rosenberg

Jan Bierma

Gregory L Hura

Roopa Thapar

...

2021/8/1

Decreased ATM protein expression is substantiated with PTEN loss in defining aggressive phenotype of prostate cancer associated with lethal disease

European Urology Open Science

Simon R Walker

Ramy Abdelsalam

Sunita Ghosh

Julie Livingstone

Nallasivam Palanisamy

...

2021/7/1

Function and molecular mechanism of the DNA damage response in immunity and cancer immunotherapy

Zu Ye

Yin Shi

Susan P Lees-Miller

John A Tainer

2021/12/14

Structural basis of long-range to short-range synaptic transition in NHEJ

Nature

Siyu Chen

Linda Lee

Tasmin Naila

Susan Fishbain

Annie Wang

...

2021/5/13

Long noncoding RNA NIHCOLE promotes ligation efficiency of DNA double-strand breaks in hepatocellular carcinoma

Cancer research

Juan P Unfried

Mikel Marín-Baquero

Ángel Rivera-Calzada

Nerea Razquin

Eva M Martín-Cuevas

...

2021/10/1

Structural insights into the role of DNA-PK as a master regulator in NHEJ

Siyu Chen

James P Lees-Miller

Yuan He

Susan P Lees-Miller

2021/8

The active DNA-PK holoenzyme occupies a tensed state in a staggered synaptic complex

Structure

Morgan Hepburn

Daniel J Saltzberg

Linda Lee

Shujuan Fang

Claire Atkinson

...

2021/5/6

Mechanism of efficient double-strand break repair by a long non-coding RNA

Nucleic acids research

Roopa Thapar

Jing L Wang

Michal Hammel

Ruiqiong Ye

Ke Liang

...

2020/11/4

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