Ryan C. Gimple

Ryan C. Gimple

Case Western Reserve University

H-index: 28

North America-United States

About Ryan C. Gimple

Ryan C. Gimple, With an exceptional h-index of 28 and a recent h-index of 28 (since 2020), a distinguished researcher at Case Western Reserve University, specializes in the field of Cancer Biology, Genomics, Epigenetics, Glioblastoma.

His recent articles reflect a diverse array of research interests and contributions to the field:

IFI35 regulates non-canonical NF-κB signaling to maintain glioblastoma stem cells and recruit tumor-associated macrophages

Lymphatic endothelial-like cells promote glioblastoma stem cell growth through cytokine-driven cholesterol metabolism

Targeting microglial metabolic rewiring synergizes with immune-checkpoint blockade therapy for glioblastoma

Sorting nexin 10 sustains PDGF receptor signaling in glioblastoma stem cells via endosomal protein sorting

Non-metabolic functions of phosphofructokinase-1 orchestrate tumor cellular invasion and genome maintenance under bevacizumab therapy

LncRNA INHEG promotes glioma stem cell maintenance and tumorigenicity through regulating rRNA 2’-O-methylation

Superenhancer activation of KLHDC8A drives glioma ciliation and hedgehog signaling

Dual role of CXCL8 in maintaining the mesenchymal state of glioblastoma stem cells and M2-like tumor-associated macrophages

Ryan C. Gimple Information

University

Position

___

Citations(all)

4026

Citations(since 2020)

3857

Cited By

1267

hIndex(all)

28

hIndex(since 2020)

28

i10Index(all)

36

i10Index(since 2020)

36

Email

University Profile Page

Case Western Reserve University

Google Scholar

View Google Scholar Profile

Ryan C. Gimple Skills & Research Interests

Cancer Biology

Genomics

Epigenetics

Glioblastoma

Top articles of Ryan C. Gimple

Title

Journal

Author(s)

Publication Date

IFI35 regulates non-canonical NF-κB signaling to maintain glioblastoma stem cells and recruit tumor-associated macrophages

Cell Death & Differentiation

Daqi Li

Xiefeng Wang

Kexin Chen

Danyang Shan

Gaoyuan Cui

...

2024/4/9

Lymphatic endothelial-like cells promote glioblastoma stem cell growth through cytokine-driven cholesterol metabolism

Nature Cancer

Linjie Zhao

Zhixin Qiu

Zhengnan Yang

Lian Xu

Thomas M Pearce

...

2024/1/3

Targeting microglial metabolic rewiring synergizes with immune-checkpoint blockade therapy for glioblastoma

Cancer discovery

Zengpanpan Ye

Xiaolin Ai

Kailin Yang

Zhengnan Yang

Fan Fei

...

2023/4/3

Sorting nexin 10 sustains PDGF receptor signaling in glioblastoma stem cells via endosomal protein sorting

JCI insight

Ryan C Gimple

Guoxin Zhang

Shuai Wang

Tengfei Huang

Jina Lee

...

2023/3/3

Non-metabolic functions of phosphofructokinase-1 orchestrate tumor cellular invasion and genome maintenance under bevacizumab therapy

Neuro-oncology

Yi Chieh Lim

Kamilla E Jensen

Diana Aguilar-Morante

Lina Vardouli

Kristoffer Vitting-Seerup

...

2023/2/1

LncRNA INHEG promotes glioma stem cell maintenance and tumorigenicity through regulating rRNA 2’-O-methylation

Nature Communications

Lihui Liu

Ziyang Liu

Qinghua Liu

Wei Wu

Peng Lin

...

2023/11/18

Superenhancer activation of KLHDC8A drives glioma ciliation and hedgehog signaling

The Journal of Clinical Investigation

Derrick Lee

Ryan C Gimple

Xujia Wu

Briana C Prager

Zhixin Qiu

...

2023/1/17

Dual role of CXCL8 in maintaining the mesenchymal state of glioblastoma stem cells and M2-like tumor-associated macrophages

Clinical Cancer Research

Wei Yuan

Qian Zhang

Danling Gu

Chenfei Lu

Deobrat Dixit

...

2023/9/15

Epigenetic and metabolic regulation of primary and metastatic brain cancers

Frontiers in Oncology

Ryan C Gimple

Briana C Prager

Qi Xie

2023

Integrative multi-omics approaches to explore immune cell functions: Challenges and opportunities

Xu Wang

Dian Fan

Yuqing Yang

Ryan C Gimple

Shengtao Zhou

2023/4/21

Leveraging allele-specific expression for therapeutic response gene discovery in glioblastoma

Cancer research

Arko Sen

Briana C Prager

Cuiqing Zhong

Donglim Park

Zhe Zhu

...

2022/2/1

β2-microglobulin maintains glioblastoma stem cells and induces M2-like polarization of tumor-associated macrophages

Cancer Research

Daqi Li

Qian Zhang

Lu Li

Kexin Chen

Junlei Yang

...

2022/9/16

Glioblastoma stem cells reprogram chromatin in vivo to generate selective therapeutic dependencies on DPY30 and phosphodiesterases

Science Translational Medicine

Deobrat Dixit

Briana C Prager

Ryan C Gimple

Tyler E Miller

Qiulian Wu

...

2022/1/5

Brain cancer stem cells: resilience through adaptive plasticity and hierarchical heterogeneity

Ryan C Gimple

Kailin Yang

Matthew E Halbert

Sameer Agnihotri

Jeremy N Rich

2022/9

PDGF signaling inhibits mitophagy in glioblastoma stem cells through N6-methyladenosine

Developmental cell

Deguan Lv

Ryan C Gimple

Cuiqing Zhong

Qiulian Wu

Kailin Yang

...

2022/6/20

ADAR1-mediated RNA editing links ganglioside catabolism to glioblastoma stem cell maintenance

The Journal of clinical investigation

Li Jiang

Yajing Hao

Changwei Shao

Qiulian Wu

Briana C Prager

...

2022/3/15

Transcription elongation machinery is a druggable dependency and potentiates immunotherapy in glioblastoma stem cells

Cancer discovery

Zhixin Qiu

Linjie Zhao

Jia Z Shen

Zhengyu Liang

Qiulian Wu

...

2022/2/1

FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells

Cell

Jia Z Shen

Zhixin Qiu

Qiulian Wu

Darren Finlay

Guillermina Garcia

...

2021/1/21

Targeting nuclear receptors for cancer therapy: Premises, promises, and challenges

Zhengnan Yang

Ryan C Gimple

Nianxin Zhou

Linjie Zhao

Jan-Åke Gustafsson

...

2021/6/1

CRISPR screening of CAR T cells and cancer stem cells reveals critical dependencies for cell-based therapies

Cancer discovery

Dongrui Wang

Briana C Prager

Ryan C Gimple

Brenda Aguilar

Darya Alizadeh

...

2021/5/1

See List of Professors in Ryan C. Gimple University(Case Western Reserve University)