Roddy O' Connor
University of Pennsylvania
H-index: 31
North America-United States
Top articles of Roddy O' Connor
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
Bendamustine lymphodepletion before axicabtagene ciloleucel is safe and associates with reduced inflammatory cytokines | Blood Advances | Guido Ghilardi Luca Paruzzo Jakub Svoboda Elise A Chong Alexander A Shestov | 2024/2/13 |
Exploiting the CD200-CD200R immune checkpoint axis in multiple myeloma to enhance CAR T-cell therapy | Blood | Yan Tang Wei Liu Siddhant Kadu Omar Johnson Zainul S Hasanali | 2024/1/11 |
TET2 regulates early and late transitions in exhausted CD8+ T-cell differentiation and limits CAR T-cell function | bioRxiv | Alexander J Dimitri Amy E Baxter Gregory M Chen Caitlin R Hopkins Geoffrey T Rouin | 2024 |
Enhancing chimeric antigen receptor T cell therapy by modulating the p53 signaling network with Δ133p53α | Proceedings of the National Academy of Sciences | Christopher Roselle Izumi Horikawa Linhui Chen Andre R Kelly Donna Gonzales | 2024/3/5 |
Type I Interferon Blockade Enhances Transduction Efficiency and Efficacy of Non-Activated CAR T Cells | Blood | Joseph Durgin Ashwin Sannecy Andre Kelly Roddy S O'Connor Saba Ghassemi | 2023/11/28 |
Current status and challenges of vaccination therapy for glioblastoma | Hamed Hosseinalizadeh Mohammad Rahmati Ammar Ebrahimi Roddy S O'Connor | 2023/4/3 | |
Suggested searches | Perspective | Sunkyung Kim Jing Chen Feiya Ou Tian-Tian Liu Suin Jo | 2024/3/4 |
442-B IL-18-enhanced non-activated CAR T-cells for improved metabolic function and therapeutic efficacy | Joseph Durgin Ashwin Sannecy Nandana Mukherjee Xiaoling Jin Andre Kelly | 2023/11/1 | |
Checkmate: Metabolic flexibility with a STING in its tail | Roddy S O’Connor | 2023/12/6 | |
Sequential Exposure to IL21 and IL15 During Human Natural Killer Cell Expansion Optimizes Yield and Function | Cancer Immunology Research | Caimei Zhang Siddhant Kadu Yansen Xiao Omar Johnson Andre Kelly | 2023/11/1 |
Bendamustine Is Less Toxic Than Fludarabine-Cyclophosphamide-Based Lymphodepletion before CD28-Costimulated CART19 through Reduced Inflammatory Cytokines | Blood | Guido Ghilardi Luca Paruzzo Jakub Svoboda Elise A Chong Alexander Shestov | 2023/11/28 |
Nicotinamide enhances natural killer cell function and yields remissions in patients with non-Hodgkin lymphoma | Science translational medicine | Frank Cichocki Bin Zhang Cheng-Ying Wu Emily Chiu Abderrahman Day | 2023/7/19 |
Rapid manufacturing of non-activated potent CAR T cells | Nature biomedical engineering | Saba Ghassemi Joseph S Durgin Selene Nunez-Cruz Jai Patel John Leferovich | 2022/2 |
Metabolic and epigenetic orchestration of (CAR) T cell fate and function | Behnia Akbari Zahra Hosseini Pardis Shahabinejad Saba Ghassemi Hamid Reza Mirzaei | 2022/12/1 | |
395 Engineering non-activated CAR T cells with enhanced potency against advanced cancers | J Immunother | Saba Ghassemi Joseph Durgin Frederic Bushman Saar Gill Roddy O’Connor | 2022 |
Physiologix™ Serum Replacement and NB-ROC™ T Cell Culture Media Combination Shows Enhanced T-Cell Transduction Efficiency for CAR-T Therapy | Blood | Asma Ayari Diana Maradze Nanami Kadota Roddy O'Connor | 2022/11/15 |
1238 Separating the wheat from the chaff: Engineering CARTs with superior metabolic attributes against solid tumors | J Immunother | Yufan Zhou Andre Kelly Andrew Frisch Decheng Song Saba Ghassemi | 2022 |
Targeting PARP11 to avert immunosuppression and improve CAR T therapy in solid tumors | Nature cancer | Hongru Zhang Pengfei Yu Vivek S Tomar Xiangjie Chen Matthew J Atherton | 2022/7 |
Enhancing CAR T function with the engineered secretion of C. perfringens neuraminidase | Molecular Therapy | Joseph S Durgin Radhika Thokala Lexus Johnson Edward Song John Leferovich | 2022/3/2 |
CAR-T cell-mediated depletion of immunosuppressive tumor-associated macrophages promotes endogenous antitumor immunity and augments adoptive immunotherapy | Nature communications | Alba Rodriguez-Garcia Rachel C Lynn Mathilde Poussin Monika A Eiva Lauren C Shaw | 2021/2/9 |
