Robert W. Sobol, PhD

Robert W. Sobol, PhD

University of South Alabama

H-index: 57

North America-United States

About Robert W. Sobol, PhD

Robert W. Sobol, PhD, With an exceptional h-index of 57 and a recent h-index of 35 (since 2020), a distinguished researcher at University of South Alabama, specializes in the field of DNA Repair & Metabolism.

His recent articles reflect a diverse array of research interests and contributions to the field:

Impact of polβ/XRCC1 Interaction Variants on the Efficiency of Nick Sealing by DNA Ligase IIIα in the Base Excision Repair Pathway

Abstract IA022: Uracil DNA glycosylase activity limits deoxyuridine contamination in genomic DNA and is essential for the type-1 interferon response in cells treated with ATR …

CometChip enables parallel analysis of multiple DNA repair activities [DNA repair 106 (2021) 103176-103202]

Deoxyuridine-rich cytoplasmic DNA antagonizes STING-dependent innate immune responses and sensitizes resistant tumors to anti-PD-L1 therapy

Mouse models to explore the biological and organismic role of DNA polymerase beta

DNA polymerase beta expression in head & neck cancer modulates the poly-ADP-ribose-mediated replication checkpoint

Base excision repair regulation of replication stress induced poly (ADP-ribose) checkpoints

A multi-scale map of protein assemblies in the DNA damage response

Robert W. Sobol, PhD Information

University

Position

Mitchell Cancer Institute

Citations(all)

12592

Citations(since 2020)

3949

Cited By

10288

hIndex(all)

57

hIndex(since 2020)

35

i10Index(all)

124

i10Index(since 2020)

86

Email

University Profile Page

Google Scholar

Robert W. Sobol, PhD Skills & Research Interests

DNA Repair & Metabolism

Top articles of Robert W. Sobol, PhD

Title

Journal

Author(s)

Publication Date

Impact of polβ/XRCC1 Interaction Variants on the Efficiency of Nick Sealing by DNA Ligase IIIα in the Base Excision Repair Pathway

Journal of Molecular Biology

Danah Almohdar

Mitchell Gulkis

Abigail Ortiz

Qun Tang

Robert W Sobol

...

2024/2/15

Abstract IA022: Uracil DNA glycosylase activity limits deoxyuridine contamination in genomic DNA and is essential for the type-1 interferon response in cells treated with ATR …

Cancer Research

Pinakin Pandya

Frank P Vendetti

Joseph A Ghoubaira

Sudipta Pathak

Joshua J Deppas

...

2024/1/9

CometChip enables parallel analysis of multiple DNA repair activities [DNA repair 106 (2021) 103176-103202]

DNA repair

Jing Ge

Le P Ngo

Simran Kaushal

Ian J Tay

Elina Thadhani

...

2021/10/1

Deoxyuridine-rich cytoplasmic DNA antagonizes STING-dependent innate immune responses and sensitizes resistant tumors to anti-PD-L1 therapy

bioRxiv

Pinakin Pandya

Frank P Vendetti

Joseph A El-Ghoubaira

Sudipta Pathak

Joshua J Deppas

...

2024

Mouse models to explore the biological and organismic role of DNA polymerase beta

Robert W Sobol

2024/4

DNA polymerase beta expression in head & neck cancer modulates the poly-ADP-ribose-mediated replication checkpoint

Cancer Research

Md Maruf Khan

Anusha Angajala

Denise Y Gibbs

Jeffrey C Liu

Camille Ragin

...

2024/3/22

Base excision repair regulation of replication stress induced poly (ADP-ribose) checkpoints

Cancer Research

Md Ibrahim

Md Maruf Khan

Rasha Q Al-Rahaleh

Jennifer Clark

Faisal Hayat

...

2024/3/22

A multi-scale map of protein assemblies in the DNA damage response

Cell Systems

Anton Kratz

Minkyu Kim

Marcus R Kelly

Fan Zheng

Christopher A Koczor

...

2023/6/21

Overexpression of the WWE domain of RNF146 modulates poly-(ADP)-ribose dynamics at sites of DNA damage

bioRxiv

Rasha Q Al-Rahahleh

Kate M Saville

Joel F Andrews

Zhijin Wu

Christopher A Koczor

...

2023

Co-creation and engagement in a DNA integrity cohort study

Journal of Clinical and Translational Science

L Lynette Parker

Chantel M Bonner

Robert W Sobol

Martha I Arrieta

2023/1

219 RESPECTUFUL CLOSURE OF A CEnR DNA INTEGRITY STUDY

Journal of Clinical and Translational Science

Martha Arrieta

Frederick P Whiddon

L Lynette Parker

Erica Sutherland

Robert W Sobol

2023/4

Targeting HSF1 for cancer treatment: Mechanisms and inhibitor development

Yeh Chin

Khanisyah E Gumilar

Xing-Guo Li

Brahmana A Tjokroprawiro

Chien-Hsing Lu

...

2023

Pol ss/XRCC1 heterodimerization dictates DNA damage recognition and basal Pol ss protein levels without interfering with mouse viability or fertility

DNA REPAIR

Christopher A Koczor

Marlo K Thompson

Nidhi Sharma

Aishwarya Prakash

Robert W Sobol

2023/3/1

A New Drug Discovery Platform: Application to DNA Polymerase Eta and Apurinic/Apyrimidinic Endonuclease 1

International Journal of Molecular Sciences

Debanu Das

Matthew AJ Duncton

Taxiarchis M Georgiadis

Patricia Pellicena

Jennifer Clark

...

2023/11/23

Polβ/XRCC1 heterodimerization dictates DNA damage recognition and basal Polβ protein levels without interfering with mouse viability or fertility

DNA repair

Christopher A Koczor

Marlo K Thompson

Nidhi Sharma

Aishwarya Prakash

Robert W Sobol

2023/3/1

DNA repair and nucleic acid therapeutics in cancer

NAR cancer

Robert W Sobol

2023/9/1

WRN suppresses p53/PUMA-induced apoptosis in colorectal cancer with microsatellite instability/mismatch repair deficiency

Proceedings of the National Academy of Sciences

Robert W Sobol

2023/1/10

Double-strand breaks: When DNA repair events accidentally meet

Shingo Fujii

Robert W Sobol

Robert P Fuchs

2022/4/1

A high-throughput 384-well CometChip platform reveals a role for 3-methyladenine in the cellular response to etoposide-induced DNA damage

NAR Genomics and Bioinformatics

Jianfeng Li

Alison Beiser

Nupur B Dey

Shunichi Takeda

Liton Kumar Saha

...

2022/9/1

Live cell detection of poly (ADP-ribose) for use in genetic and genotoxic compound screens

Cancers

Christopher A Koczor

Aaron J Haider

Kate M Saville

Jianfeng Li

Joel F Andrews

...

2022/7/28

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