Robert P Mecham

Robert P Mecham

Washington University in St. Louis

H-index: 94

North America-United States

About Robert P Mecham

Robert P Mecham, With an exceptional h-index of 94 and a recent h-index of 41 (since 2020), a distinguished researcher at Washington University in St. Louis, specializes in the field of Extracellular matrix, vascular development, lung biology.

His recent articles reflect a diverse array of research interests and contributions to the field:

Constitutive Modeling of Mouse Arteries Suggests Changes in Directional Coupling and Extracellular Matrix Remodeling That Depend on Artery Type, Age, Sex, and Elastin Amounts

Multi‐organ phenotypes in mice lacking latent TGFβ binding protein 2 (LTBP2)

Targeting epidermal growth factor receptor to stimulate elastic matrix regenerative repair

Progerin induces a phenotypic switch in vascular smooth muscle cells and triggers replication stress and an aging-associated secretory signature

DISTINCT PATTERNS OF SMOOTH MUSCLE PHENOTYPIC MODULATION IN THORACIC AND ABDOMINAL AORTIC ANEURYSM

A new mouse model of elastin haploinsufficiency highlights the importance of elastin to vascular development and blood pressure regulation

SVEP1 is an endogenous ligand for the orphan receptor PEAR1

Polarized localization of phosphatidylserine in the endothelium regulates Kir2. 1

Robert P Mecham Information

University

Position

Alumni Endowed Professor of Cell Biology and Physiology School of Medicine

Citations(all)

31259

Citations(since 2020)

7059

Cited By

27530

hIndex(all)

94

hIndex(since 2020)

41

i10Index(all)

311

i10Index(since 2020)

180

Email

University Profile Page

Washington University in St. Louis

Google Scholar

View Google Scholar Profile

Robert P Mecham Skills & Research Interests

Extracellular matrix

vascular development

lung biology

Top articles of Robert P Mecham

Title

Journal

Author(s)

Publication Date

Constitutive Modeling of Mouse Arteries Suggests Changes in Directional Coupling and Extracellular Matrix Remodeling That Depend on Artery Type, Age, Sex, and Elastin Amounts

Journal of Biomechanical Engineering

Keshav A Kailash

Jie Z Hawes

Austin J Cocciolone

Matthew R Bersi

Robert P Mecham

...

2024/3/1

Multi‐organ phenotypes in mice lacking latent TGFβ binding protein 2 (LTBP2)

Nicholas K Bodmer

Russell H Knutsen

Robyn A Roth

Ryan M Castile

Michael D Brodt

...

2024/2

Targeting epidermal growth factor receptor to stimulate elastic matrix regenerative repair

Tissue Engineering Part A

Simran Dayal

Thomas Broekelmann

Robert P Mecham

Anand Ramamurthi

2023/4/1

Progerin induces a phenotypic switch in vascular smooth muscle cells and triggers replication stress and an aging-associated secretory signature

Geroscience

Nuria Coll-Bonfill

Urvashi Mahajan

Elena V Shashkova

Chien-Jung Lin

Robert P Mecham

...

2023/4

DISTINCT PATTERNS OF SMOOTH MUSCLE PHENOTYPIC MODULATION IN THORACIC AND ABDOMINAL AORTIC ANEURYSM

Journal of the American College of Cardiology

Chien-Jung Lin

Campbell Keating

Robyn Roth

Chieh-Yu Lin

Robert Mecham

2023/3/7

A new mouse model of elastin haploinsufficiency highlights the importance of elastin to vascular development and blood pressure regulation

Matrix Biology

Bridget M Brengle

Michelle Lin

Robyn A Roth

Kara D Jones

Jessica E Wagenseil

...

2023/3/1

SVEP1 is an endogenous ligand for the orphan receptor PEAR1

Nature communications

Jared S Elenbaas

Upasana Pudupakkam

Katrina J Ashworth

Chul Joo Kang

Ved Patel

...

2023/2/15

Polarized localization of phosphatidylserine in the endothelium regulates Kir2. 1

JCI insight

Claire A Ruddiman

Richard Peckham

Melissa A Luse

Yen-Lin Chen

Maniselvan Kuppusamy

...

2023/5/5

Impacts of Microfibril-Associated Glycoprotein 1 and 2 Deficiency in Bleomycin-Induced Pulmonary Fibrosis

J Koenitzer

SL Brody

RP Mecham

BD Humphreys

2022/5

Increases in hydraulic conductance and solute permeability in a mouse model of ascending thoracic aortic aneurysm

Journal of biomechanics

Christie L Crandall

Sean Y Kim

Jacob Rother

Vivian S Lee

Robert P Mecham

...

2022/12/1

JAGGED1/NOTCH3 activation promotes aortic hypermuscularization and stenosis in elastin deficiency

The Journal of Clinical Investigation

Jui M Dave

Raja Chakraborty

Aglaia Ntokou

Junichi Saito

Fatima Z Saddouk

...

2022/3/1

LTBP1 promotes fibrillin incorporation into the extracellular matrix

Matrix Biology

Matthias Przyklenk

Veronika S Georgieva

Fabian Metzen

Sebastian Mostert

Birgit Kobbe

...

2022/6/1

JNK2 Gene Silencing for Elastic Matrix Regenerative Repair

Tissue Engineering Part A

Sarah Carney

Tom Broekelmann

Robert Mecham

Anand Ramamurthi

2022/3/1

Mutation in the matricellular gene fibulin-4 leads to endothelial dysfunction in resistance arteries

bioRxiv

Michelle Lin

Kara Jones

Bridget M Brengle

Robert P Mecham

Carmen M Halabi

2022/5/21

The internal elastic lamina of resistance arteries facilitates vasodilation

The FASEB Journal

Claire A Ruddiman

Victoria Milosek

Richard Peckham

Robert P Mecham

Jessica E Wagenseil

...

2022/5

Progerin triggers a phenotypic switch in vascular smooth muscle cells that causes replication stress and an aging-associated secretory signature

bioRxiv

Nuria Coll-Bonfill

Urvashi Mahajan

Chien-Jung Lin

Robert P Mecham

Susana Gonzalo

2022/2/5

Passive biaxial mechanical behavior of newborn mouse aorta with and without elastin

Journal of the mechanical behavior of biomedical materials

Jungsil Kim

Austin J Cocciolone

Marius C Staiculescu

Robert P Mecham

Jessica E Wagenseil

2022/2/1

Endothelial dysfunction drives aneurysm development in Marfan syndrome

The FASEB Journal

Anna Cantalupo

Keiichi Asano

Jens Hansen

Carmen Halabi

Robert Mecham

...

2022/5

SVEP1 is a human coronary artery disease locus that promotes atherosclerosis

Science translational medicine

In-Hyuk Jung

Jared S Elenbaas

Arturo Alisio

Katherine Santana

Erica P Young

...

2021/3/24

Early aberrant angiogenesis due to elastic fiber fragmentation in aortic valve disease

Journal of Cardiovascular Development and Disease

Robert B Hinton

Amy L Juraszek

Amy M Opoka

Benjamin J Landis

J Michael Smith

...

2021/6/25

See List of Professors in Robert P Mecham University(Washington University in St. Louis)