Robert J. Lefkowitz
Duke University
H-index: 252
North America-United States
Top articles of Robert J. Lefkowitz
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
G protein–coupled receptors: from radioligand binding to cellular signaling | The Journal of Clinical Investigation | Howard A Rockman Robert J Lefkowitz | 2024/3/1 |
Structure and dynamics determine G protein coupling specificity at a class A GPCR | bioRxiv | Marina Casiraghi Haoqing Wang Patrick Brennan Chris Habrian Harald Hübner | 2024/3/29 |
Molecular insights into G protein specificity and biased agonism at the β 2-adrenergic receptor | bioRxiv | Marina Casiraghi Haoqing Wang Patrick Brennan Chris Habrian Harald Hübner | 2024/3/29 |
System and method for homogenous gpcr phosphorylation and identification of beta-2 adrenergic receptor positive allosteric modulators | 2024/3/28 | ||
Loss of biased signaling at a G protein-coupled receptor in overexpressed systems | Plos one | Angus Li Samuel Liu Rennica Huang Seungkirl Ahn Robert J Lefkowitz | 2023/3/24 |
How carvedilol does not activate β2-adrenoceptors | Robert J Lefkowitz Howard A Rockman Paul J Shim Samuel Liu Seungkirl Ahn | 2023/11/30 | |
Calcium fluorimetry with the FLIPR Calcium 6 kit on FlexStation 3 | Angus Li Samuel Liu Rennica Huang Seungkirl Ahn Robert J Lefkowitz | 2023/2/28 | |
Signal transduction at GPCRs: Allosteric activation of the ERK MAPK by β-arrestin | Proceedings of the National Academy of Sciences | Alem W Kahsai Kunal S Shah Paul J Shim Mason A Lee Bowie N Shreiber | 2023/10/24 |
Whole-cell radioligand binding for receptor internalization | Angus Li Samuel Liu Rennica Huang Seungkirl Ahn Robert J Lefkowitz | 2023/2/28 | |
Allosteric modulator potentiates β2AR agonist–promoted bronchoprotection in asthma models | The Journal of Clinical Investigation | Seungkirl Ahn Harm Maarsingh Julia KL Walker Samuel Liu Akhil Hegde | 2023/9/15 |
Whole-cell radioligand saturation binding | Angus Li Samuel Liu Rennica Huang Seungkirl Ahn Robert J Lefkowitz | 2023/2/28 | |
Abstract P2154: A Novel Allosteric Modulator Of The β1AR Identified By DNA-encoded Small Molecule Library Screening Demonstrates Unique Pharmacology And … | Circulation Research | Alyssa Grogan Seungkirl Ahn David Israel Alex Shaginian Qiuxia Chen | 2023/8/4 |
Marc G. Caron (1946–2022) | Nature Neuroscience | Robert J Lefkowitz Susan G Amara | 2022/9 |
Compositions and Methods for the Treatment of Intracranial Diseases | 2022/8/18 | ||
GPCR-mediated β-arrestin activation deconvoluted with single-molecule precision | Cell | Wesley B Asher Daniel S Terry G Glenn A Gregorio Alem W Kahsai Alessandro Borgia | 2022/5/12 |
Loss of Biased Signaling Specificity of the Angiotensin II Type 1 Receptor in Overexpressed Systems | The FASEB Journal | Angus Li Samuel Liu Rennica Huang Seungkirl Ahn Robert J Lefkowitz | 2022/5 |
Translating science to medicine: the case for physician-scientists | Paul J Utz Mukesh K Jain Vivian G Cheung Brian K Kobilka Robert Lefkowitz | 2022/2/16 | |
Beta-Arrestin-Modulating Compounds and Methods of Using Same | 2022/10/6 | ||
β-Arrestin–biased allosteric modulator potentiates carvedilol-stimulated β adrenergic receptor cardioprotection | Molecular Pharmacology | Jialu Wang Biswaranjan Pani Ilhan Gokhan Xinyu Xiong Alem W Kahsai | 2021/12/1 |
Unique Positive Cooperativity Between the β-Arrestin–Biased β-Blocker Carvedilol and a Small Molecule Positive Allosteric Modulator of the β2-Adrenergic Receptor | Molecular Pharmacology | Biswaranjan Pani Seungkirl Ahn Paula K Rambarat Shashank Vege Alem W Kahsai | 2021/11/1 |
Co-Authors
